Every Regeneron International Science and Engineering Fair project Fairfolio holds: 17,565 entries across 13 years, with the abstract, category and awards the fair published for each one.
Counts cover every year of this fair and use its own category labels, exactly as the source published them. Each one links to that category's ISEF projects.
17565 projects · showing 1951–1980
ISEF · 2025
Systems Software
Traditional operating systems use multiple abstraction layers that simplify development but restrict customization and optimization. Gate OS, a Rust-based exokernel, minimizes abstraction ov…
ISEF · 2025
Physics and Astronomy
The purpose of this experiment was to test the strength of 3D-printed gears with different infill levels. Infill refers to how much material is used for the inner portion of an item. This id…
ISEF · 2025
Mathematics
The occurrence of Pi in the Mandelbrot set is a phenomenon which has been known since its discovery in 1991. It has enjoyed great popularity among mathematicians ever since, even appearing o…
ISEF · 2025
Animal Sciences
Fire ants cause billions of dollars of economic damage every year, and common control methods kill all insects in a given area, even advantageous ones. As my local community is highly effect…
ISEF · 2025
Biochemistry
Oligonucleotides, especially siRNAs, have been identified as a point of interest due to their capability for precision targeting of "undruggable" targets. siRNAs (Small Interfering RNA) bind…
ISEF · 2025
Mathematics
Generating all possible Feynman diagrams is crucial in quantum field theory for computing interaction amplitudes. In scalar phi-4 theory, characterized by four-point interaction vertices, th…
ISEF · 2025
Robotics and Intelligent Machines
Accurate prediction of gene expression from chromatin accessibility data is essential for understanding transcriptional regulation across cell types. While the General Expression Transformer…
ISEF · 2025
Mathematics
Linear systems of equations are fundamental for scientific and engineering projects. Yet, traditional methods of solving linear systems struggle with scalability(speed) , instability, and ar…
ISEF · 2025
Materials Science
Quasicrystals are materials with ordered but aperiodic atomic arrangements, which can be contrasted from traditional crystals that possess a periodic structure. Their unique thermal and elec…
ISEF · 2025
Embedded Systems
Background: Grasping is a critical function for humanoid robots to automate mechanical labor. Current robotic grasping is limited by the inability to precisely set grasping conditions before…
ISEF · 2025
Embedded Systems
This study addressed the engineering challenge: can a low cost, microcontroller based device reliably detect and visually represent alerts in real time for individuals with hearing impairmen…
ISEF · 2025
Earth and Environmental Sciences
Global Microplastic Pollution, an “Environmental Ticking Time Bomb”, is a significant and ongoing threat to the environment, world's water-quality, and human-health. Humans now ingest >5 gra…
ISEF · 2025
Microbiology
Aliivibrio fischeri is a single-celled, gram-negative, rod-shaped bacterium that lives within the ocean. When in healthy waters, its cell membrane quorum senses with other bacterium near it…
ISEF · 2025
Biomedical and Health Sciences
The use of GLP-1 agonists, including Ozempic and Exenatide, has increased by almost 40-fold between 2017 and 2021. These drugs are widely used to regulate glucose metabolism in type 2 diabet…
ISEF · 2025
Energy: Sustainable Materials and Design
Graphene Solar Fuel Generator (GSFG) is a new generation green fuel production technology based on advanced graphene-based solar technology to generate methane (CH4) from carbon dioxide (CO2…
ISEF · 2025
Robotics and Intelligent Machines
Multimodal contents' increasing complexity poses significant challenges for Vision-Language Models (VLMs), particularly in hateful video detection. Hateful videos are inherently multimodal a…
ISEF · 2025
Biomedical and Health Sciences
Cognitive decline poses a significant public health challenge among aging populations. Green tea contains epigallocatechin gallate (EGCG), a catechin widely hypothesized to protect against n…
ISEF · 2025
Biomedical and Health Sciences
Today, up to 3.6 million Americans suffer from Inflammatory Bowel Disease (IBD) —a group of debilitating conditions, including Crohn’s disease and ulcerative colitis, that cause chronic infl…
ISEF · 2025
Embedded Systems
This project aimed to address problems inherent in fin-controlled rocketry systems. Common problems include cost, complexity, and size, and this project solved them by creating a simple, low…
ISEF · 2025
Plant Sciences
In this study, a salt-tolerant bacterium, Oceanobacillus aidingensis, referred as Oc2, was isolated from wetlands in Taiwan. In the absence of plant, Oc2 does not reduce soil salinity; howev…
ISEF · 2025
Systems Software
Cognitive decline and fine motor skill deterioration are common in the aging process, contributing to diminished quality of life and increased dementia risk. This study introduces HandNBrain…
ISEF · 2025
Technology Enhances the Arts
Nearly 5% of the global population, or 430M people, require hearing loss rehabilitation, while in the U.S., about 11M people experience serious hearing difficulties. Many deaf individuals co…
ISEF · 2025
Translational Medical Science
One in 14 people is affected by Alzheimer's Disease (AD), a progressive neurodegenerative disorder that impairs cognitive function and daily activities, resulting in a declined quality of pa…
ISEF · 2025
Behavioral and Social Sciences
Bipolar disorder (BD) complications extend beyond mood swings, with up to 60% of patients experiencing cognitive deficits even during euthymia. Key areas affected include attention, executiv…
ISEF · 2025
Microbiology
The World Health Organization reports Vibrio cholerae serogroup O139 as a high-priority pathogen that has the potential to precipitate the 8th cholera pandemic. This project explores the use…
ISEF · 2025
Energy: Sustainable Materials and Design
Despite 70% of our planet being covered by water, only 3% of that is fresh water, with the vast majority being saline. World WildLife predicts that two-thirds of the world’s population may f…
ISEF · 2025
Biomedical Engineering
The tumor suppressor protein p53, is mutated in 50% of human cancers. DNA damage activates kinases which stabilize p53 through phosphorylation and paradoxically can promote cancer cell survi…
ISEF · 2025
Cellular and Molecular Biology
Although CAR T-cell therapy has significantly improved treatment outcomes for hematologic B-cell malignancies, challenges such as relapse and mortality rates (35-50% within 6-12 months post-…
ISEF · 2025
Translational Medical Science
Chronic wounds are a major health concern, especially among the elderly and people with conditions like diabetes. Without proper treatment, they can lead to infection, tissue loss, or even a…
ISEF · 2025
Behavioral and Social Sciences
As of 2022, 49% of U.S. adolescents and 25% of adults have psychological disorders, with 60% also experiencing gastrointestinal disorders. The aim of the current study is to determine whethe…