38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
CYSF · 2026
Silver Medal
This project looks at human stem cells (induced pluripotent stem cells) and how they respond when one of the PRPF4B alleles are made non-functional using CRISPR Cas-9. The goal is to see if…
ISEF · 2026
Computational Biology and Bioinformatics Fourth Award
This project aims to better predict cancer dynamics to mitigate the effects of drug resistance. This research project uses a dataset from Kaznatcheev et al., who created an evolutionary game…
CSEF · 2026
Computational Science (Senior Division)
Data is easily the most important aspect of training machine learning and deep learning models, as large amounts of high-quality data are required for these models to understand the intricac…
CSEF · 2026
Zoology (Senior Division)
In this study, Danio rerio (zebrafish) were exposed to 0.25% (2.5g/L) dextran sulfate sodium (DSS) for five days to induce intestinal epithelial cell damage. After DSS exposure, the experime…
ISEF · 2026
Earth and Environmental Sciences
Over 75,000 wildfires occurred in North America in 2025. Smoke and ash from these fires contribute to both air and water pollution. Over 5,000 of these wildfires impacted the Great Lakes as…
ISEF · 2026
Translational Medical Science
Strokes are a leading cause of disability and death in adults in the US and globally. Approximately 40% of stroke survivors develop aphasia, an acquired language and communication disorder t…
CSEF · 2026
Chemistry (Senior Division)
Peptide sequence determines its structure, function, ability to exhibit self-assembly behavior, and stimuli responsiveness. Different cysteine-containing amino acid sequences were synthesize…
ISEF · 2026
Materials Science
Conventional surfboards are predominantly manufactured using petroleum-based foams and resins that are energy-intensive, toxic to produce, and non-recyclable, contributing to significant lon…
CWSF · 2026
Disease & Illness Gold Medal
Conventional chemotherapy often fails due to systemic toxicity and acquired drug resistance. To address this, I developed a multi-targeted therapeutic matrix using synergistic phytochemicals…
AJAS · 2026
Microbiology (inferred)
Antibiotics have revolutionized medicine, saving countless lives since the introduction of penicillin. However, antimicrobial resistance has challenged their efficacy, prompting ongoing effo…
ISEF · 2026
Earth and Environmental Sciences
Natural resources worldwide, especially in coastal areas such as the Aunu'u wetlands of American Samoa, are threatened by salinity. Adaptive management strategies primarily require considera…
ISEF · 2026
Environmental Engineering
Heavy metal pollution caused by activities such as improper disposal of mining waste, ore smelting, and the burning of fossil fuels by automobiles or power plants is especially prevalent in…
ISEF · 2026
Biomedical and Health Sciences
Mutations in the FLT3 receptor, present in approximately one third of patients with acute myeloid leukemia (AML), are associated with an aggressive course of the disease, a high risk of rela…
ISEF · 2026
Environmental Engineering
We wanted to do this project to show the importance of ph levels on soil and plant health and to prove there's organic yet effective ways to solve problems. We wanted to know which organic a…
ISEF · 2026
Biomedical and Health Sciences Fourth Award
Immune thrombocytopenia (ITP), a life-threatening disorder of humans and dogs, leads to spontaneous bleeding from antibody-mediated platelet destruction. Standard immunosuppressive therapies…
ISEF · 2026
Earth and Environmental Sciences
This investigation examined whether untreated sargassum and sargassum treated with a wax coating can function as efficient absorbents of hydrocarbons in seawater. The research question guidi…
CSEF · 2026
Environmental Engineering (Track 2) (Junior Division) Honorable_mention Award
An overwhelming 98% of US individuals show detectable levels of Per- and Polyfluoroalkyl Substances (PFAS) and phthalates—ubiquitous environmental chemicals found in everyday consumer produc…
CWSF · 2026
Agriculture, Fisheries & Food
All over the world, drought is an increasing issue that is a major threat to our produce. To try and help minimize that problem, I decided to test different plant watering methods and see wh…
ISEF · 2026
Animal Sciences
Hydra are aquatic invertebrates with decentralized nervous systems, meaning their neurons are completely dispersed throughout their bodies. These organisms possess the most basal nervous sys…
ISEF · 2026
Embedded Systems
Visual impairment limits access to printed information, environmental awareness and timely assistance, especially for students and individuals who rely heavily on Braille or caregivers. To a…
ISEF · 2026
Translational Medical Science
Around 40% of the world's population (approximately 3.3 billion people) are at risk of developing cancer at some point in their lives. TP53 (Tumor Protein 53) is a gene altered in most human…
CSEF · 2026
Zoology (Senior Division)
Brine shrimp are the backbone of the marine-bio ecosystem. Lots of other animals depend on them for food, so when the environment changes it is critical for the brine shrimp; it does not jus…
CWSF · 2026
Digital Technology Silver Medal
EvoNash: Accelerating Convergence to Nash Equilibrium Investigating Adaptive Mutation Rates in Genetic Neural Networks This experiment investigates the efficiency of evolutionary algorithms…
AJAS · 2026
In-lab research with well-controlled experimental tasks and conditions will likely miss important aspects of children's functional hearing in their everyday auditory environments. In this on…
ISEF · 2026
Plant Sciences
Ventenata is an invasive grass species known for disrupting native ecosystems and agricultural lands. Currently, there are few methods of controlling this species, including chemical sprays,…
ISEF · 2026
Biomedical and Health Sciences
Alzheimer’s disease is a neurodegenerative disorder strongly tied to Amyloid-ß aggregation, leading to cellular dysfunction and an inhibition of movement. In the Caenorhabditis elegans CL200…
ISEF · 2026
Behavioral and Social Sciences Second Award
Racial disparities in federal sentencing have long raised concerns about fairness and the effectiveness of policies intended to mitigate them. This study examines whether judicial adherence…
ISEF · 2026
Plant Sciences Third Award
Increasing concentrations of metals in groundwater and waterways that are leached from coal ash ponds threaten aquatic life and drinking water quality. Phytoremediation poses a potential sol…
AJAS · 2026
Earth and Environmental Sciences (inferred)
By 2025, the Food and Agriculture Organization says around 1.8 billion people will face severe water scarcity (FAO). In Nebraska, while we rely on groundwater, we should make sure our water…
CWSF · 2026
Disease & Illness Platinum Award
Over 98% of potential therapeutics for neurological diseases fail because they cannot cross the blood-brain barrier (BBB). Current screening methods for novel ligands often focus too heavily…