Computational Biology and Bioinformatics
Of the over 100 types of cancers that together claim 2,000 lives in the United States daily, neuroblastoma is the most common in children under the age of two. This project seeks to identify…
Physics and Astronomy
Major solar flares (X&M-class) and their resulting Coronal Mass Ejections (CME) and Solar Proton Events (SPE) severely threaten modern human society. A major solar event hitting Earth would…
Microbiology
Neurodegenerative disorders affect more than 6 million people in the United States alone. Heavy metal exposure has been implicated in the progression of disorders such as Parkinson’s Disease…
Translational Medical Science
Small-cell lung cancer (SCLC) is a highly aggressive form of lung cancer. Despite available chemotherapeutics, resistance develops rapidly, accounting for a 6%, 5-year survival rate. Strateg…
Translational Medical Science
This study developed and characterized a novel proteolysis targeting chimera (PROTAC) incorporating a beta hairpin sequence motif. PROTACs facilitate the proteasomal degradation of ‘undrugga…
Biochemistry
The aim of this work was to develop a more effective biligand inhibitor for protein kinase CK2, an effective synthesis for it and characterize its binding ability to CK2. This was accomplish…
Chemistry
Previous research has revealed the strong fluorescence of 4-Hydroxy-1,3-Thiazoles and enabled their various applications. However they have never been tested on their suitability in fluoresc…
Chemistry
Wearable devices are now very popular and are used widely in health monitoring and sports training. To address the problem of limited battery life of devices, self-powered energy harvesting…
Chemistry
Firefighters suffer from burns annually; in 2018, 2835 U.S. firefighters received burn injuries. Existing heat-resistant fabrics have noncontiguous areas, and facemasks are often removed in…
A multitargeted approach is suggested to be most effective in inhibiting the formation of tau aggregates in Alzheimer’s disease. Two promising targets for treatment of Alzheimer’s are the in…
Arsenic contamination of drinking water poses an acute threat to human health, which is especially compounded in regions with limited resources. Though it is detectable, conventional tests f…
Chemistry
Coordination complexes of lanthanides possess bright luminescence with high quantum yields and long lifetimes. This allows applying them in a variety of fields such as: optoelectronics, cryp…
Materials Science
One of the problems faced by farmers is the devaluation of their products in the post-harvest period. Bioconstructions for storing agricultural products are sustainable and cheap alternative…
Biomedical and Health Sciences
Immunotherapy is a treatment in which the body’s immune cells, are stimulated to fight diseases such as cancer. Several immunotherapies have been developed with the aim of helping T Cells ta…
Biomedical and Health Sciences
Nanoparticles (NPs) are attractive cancer drugs but cannot target cancer cells, causing side effects in cancer therapy. To tackle this challenge, I developed NPs that could kill breast cance…
Materials Science
Tumor-mediated immunosuppression allows tumors to hide from the immune system and avoid recognition. To reverse this suppressive microenvironment, antigen-presenting cells (APCs) and other i…
Tumor-mediated immunosuppression allows tumors to hide from the immune system and avoid recognition. To reverse this suppressive microenvironment, antigen-presenting cells (APCs) and other i…
Physics and Astronomy
Temperature field measurement, especially real-time monitoring, has undeniable value in various aspects, but when the field is of uneven gas and high temperature, there’re still imperfection…
Robotics and Intelligent Machines
In my project, I wanted to find out what method, out of the ones that I tested, would best train a neural network. Testing these methods is important because neural networks are used on a wi…
Energy: Sustainable Materials and Design
Initially, solar cells were made from silicon, but it was very expensive to get. Later on, scientists created dye-sensitized solar cells using ruthenium dye which was a pollutant and it was…
Central Virginia Governor’s School The purpose of this experiment was to compare the power output capabilities of a prototype single and double axis solar tracker. An artificial light source…
Biomedical and Health Sciences
The research was aimed at testing the effects of the polyphenolic compound Epigallocatechin-3-gallate on three colorectal cancer cell lines. The effects of this substance have been observed…
Environmental Engineering
Although water seems endlessly available, only 2.5% of the Earth’s water is fresh, with just 0.26% of that residing on the surface. This water supply is where much of humanity’s drinking wat…
Environmental Engineering
This project aims to develop a new, applicable, eco-friendly and efficient method to remove hazardous dye substances that are released into peripheral water bodies from textile factories as…
Engineering Mechanics
When one sees an airplane take off, one wonders how an object so heavy, weighing tons, can lift off with ease. Thanks to complex aeronautics and aerodynamics airplanes are able to perform a…
Embedded Systems
The electrical devices used in this day and age are plentiful and useful, however there are only a select few ways to interface with these devices. While for some, the tiny buttons on tiny s…
Animal Sciences
Honeybees store nectar in the crop(social stomach) and share it with nestmates through trophallaxis. This behavior seems to increase the risk of infections by colony members sharing contamin…
Ms. Pamela Agbu, Doctoral Candidate More than 30 million Americans have diabetes. The most prevalent is type 2 diabetes mellitus, which is characterized by insulin resistance. Resveratrol, a…
Pharmaceutical contamination of ground and surface water is a growing issue and wastewater has been identified as the main route of entry. Because they are bioactive, pharmaceuticals do not…
Allyson Andrews The purpose of this project is to determine which of the three pesticides I created is the most effective in deterring pests while maintaining the functionality of commercial…