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JQ1 Epigenetic Modulation of Pancreatic Beta-Cells (INS-1) Normalizes Glucose Sensitivity Under Hyperglycemia: Therapeutic Preventive Implications for Type II Diabetes Mellitus

Biochemistry

Chronic hyperinsulinemia and insulin resistance are prequels to type II diabetes mellitus. Previous studies from our laboratory have demonstrated that the Bromodomain-and-Extra-Terminal prot…

Jumping Genes: A Potential Molecular Target for Alzheimer's Disease Intervention

Biomedical and Health Sciences

Alzheimer's Disease(AD) affects more than 6 million people in the US, by causing degeneration of the brain cells, deficiency of cognition and mobility, and even death. As aging progresses, s…

Keeping an Eye on Children: A Swimmer-following Vehicle Enabled by Edge Intelligence

Embedded Systems

Drowning incidents involving children in pools often result from human oversight. Prior research has highlighted the early warning potential of deep learning-based object detection methods.…

Kelvin-Helmholtz Instability: Studying the Effects of Density and Velocity on Vortex Formations

Physics and Astronomy

Kelvin-Helmholtz Instability (KHI) is a process that forms vortices in fluids and occurs when two fluids in contact move in opposite directions. The Richardson Number, proportional to the de…

Ketones Produced by Bacillus subtilis Bacteria: Assessing Inhibition and Morphological Changes on Deadly Bat Fungus, Pseudogymnoascus destructans (Year 9)

Microbiology Fourth Award

Bats, like bees, are a keystone species benefiting the environment and saving farmers billions of dollars in chemicals. However, since 2006, millions of bats in North America have died of a…

Kinetic Assemblies: A Complete Solution for PCB Assembly

Engineering Technology: Statics & Dynamics

Kinetic Assemblies is a comprehensive solution for populating printed circuit boards (PCBs) on a medium scale. The medium scale is defined as a number between 300 and 600 PCBs, which falls i…

Labelling of Antibodies by Nanoparticles and Their Utilization in the Analysis of the Biological Samples

Chemistry

Immunochemical methods are commonly used for the analysis of biological samples not only in diagnostics but also in primary research. Based on the unique reaction between antibody and antige…

Language Models as Catalysts in EEG-Based BCI Speller Systems: A Low-Cost Solution for Paralyzed Patients

Neuromuscular conditions, including amyotrophic lateral sclerosis, stroke, spinal cord injury, and cerebral palsy, are affecting nearly fourteen million people globally, hindering their abil…

LeAF: Leveraging Convolutional Neural Networks for Plant Anomaly Detection and Classification for Farmers with Large Language Models for Natural Language Interaction

Farmers face numerous challenges in crop cultivation, particularly in monitoring and maintaining plant health. Plant anomalies such as pests, diseases, and weeds are critical indicators of p…

Leaf-Mining Weevil's Destruction Rate Against Invasive Coccinia grandis in Saipan

Earth and Environmental Sciences

The invasive spread of Coccinia grandis poses a significant threat to native vegetation in tropical regions, including Saipan and Guam, where it has been documented to cause serious damage.…

Learning and Long-Term Memory Are Found in Sea Urchin

Animal Sciences

On the coast of Japan, the sea urchins (Heliocidaris crassispina) of the same species gather together, while they are separated from their enemy, or the starfish (Patiria pectinifera). We fo…

Learning from Mistakes: The Benefit of Incorrect Worked Examples

Behavioural and Social Sciences (inferred)

Traditionally, math classes have followed the same format- learn the lesson, and then go home and do the homework. While this may seem like an effective way to teach material, it has been fo…

Leveraging Deep Learning Models to Identify Structurally Adequate Drug Candidates for Parkinson's Disease

Computational Biology and Bioinformatics Third Award

Parkinson's Disease (PD) is a neurodegenerative disease that causes gradual impairment of an individual through mutations in the SNCA (Synuclein Alpha) gene. Currently, there exist no widely…

Leveraging Electrochemistry and Light Scattering to Improve Air Quality Detection

Environmental Engineering

With an estimated 6.7 million people dying from air pollution annually, and millions of others suffering from illnesses that are either caused or exacerbated by this epidemic, the AQI has be…

Lifestyle Synchronization of Medullary Sponge Kidney Patients

Translational Medical Science Fourth Award

Despite its incurable nature, MSK Life Sync offers AI-driven support to manage Medullary Sponge Kidney (MSK) disease to enhance life quality for sufferers, including children. As highlighted…

Lift Them Up: A Pulley Stair Lift for Paraplegics

Applied Mechanics & Structures First Award

Light-driven Adaptive Camouflage Structures Based on Photoprogrammable Printing Ink

Chemistry Fourth Award

In nature, many animals change their colors or shapes to adapt to various environments, sparking a research trend in environmental adaptive materials. Light-responsive cholesteric liquid cry…

Lighting the Path to Photosynthetic Efficiency in Vertical Farming

Plant Sciences

80% of deforestation across the globe happens for agricultural purposes, with much deforestation resulting in unrecoverable land. However, with over 1.3 billion people suffering from food in…

Light Now

Engineering Technology: Statics & Dynamics

This paper describes the creation of a device called "LIGHT NOW", which measures the manual reaction time to a visual stimulus. Furthermore, it is capable of collecting data that, once analy…

Lightweight Walking Aid Ankle Exoskeleton Using Twisted String Actuator

Biomedical Engineering

Walking, constituting a significant portion of human energy expenditure, has spurred research into ankle exoskeletons aimed at mitigating energy consumption. Various exoskeleton designs have…

Like Trying To Find a Needle in a Blood Sac: Novel Hemostatic Gelatin Microneedle Adhesive (Gel MNA) Polymerized With Commercial Coagulation Agents Achieves Accessible Hemorrhage Treatment

Biomedical Engineering

Hemorrhage, excessive loss of blood that is expressed through eventual shock and death, is one of the leading killers worldwide. Current methods of preventing hemorrhage have many side effec…

Linear Group of Seventh Chord Transformations

Mathematics Fourth Award

Seventh chords are widely used in music. What are the relationships between different seventh chords? Can these relationships be explained mathematically? This research classifies transforma…

Linear vs. Parabolic Concentrated Solar- Thermal Power

Energy: Sustainable Materials and Design

My experiment involving concentrated solar-thermal power investigated the efficiency of linear and parabolic energy systems for heat production targeting to identify the most effective model…

LinkDev: A Programming Language That Combines All Programming Languages Into One Designed To Boost Coding Experience

Systems Software

Purpose: Programming language diversity spurs development but also induces community fatigue. The research aims to create a new language addressing this issue, promoting learning and profess…

LISES: Legislative Information Simplification and Enhancement System for Mitigating Information Asymmetry in Governmental Policies

Systems Software Fourth Award

The goal of this study was to create an enhanced yet accessible system to generate simplified summaries of governmental policies, thus enhancing public understanding and mitigating informati…

Lithium Iron Phosphate Promotes Tumor Cell Growth by Shaping Mitochondrial Function

Biomedical and Health Sciences Fourth Award

Water pollution is a critical threat to human health as it can lead to increased cancer risk. More than 22 carcinogens can be found in the drinking water, including heavy metals such as lead…

Lithium Iron Phosphate Promotes Tumor Cell Growth by Shaping Mitochondrial Function

Water pollution is a critical threat to human health as it can lead to increased cancer risk. More than 22 carcinogens can be found in the drinking water, including heavy metals such as lead…

Localization of Frontotemporal Dementia Risk Gene RAB38 to Glutamatergic Neurons: Implications for Selective Neuronal Vulnerability

Frontotemporal dementia (FTD) is a leading type of early -onset dementia caused by progressive neurodegeneration in the frontal and temporal lobes of the brain, resulting in significant alte…

Locking the SUMO Switch: Design of Small Molecules to Inhibit Rhes SUMOylation Sites for Huntington’s Disease

Biochemistry

Huntington’s disease (HD) is a terrible neurodegenerative disorder, claiming the lives of 2.27 million people annually. HD is caused by an increase in the soluble and mutant forms of the hun…

Low-Cost, Adjustable, Pediatric Prosthetic Leg

The loss of a limb severely diminishes an individual’s ability to function independently, hindering participation in society. The majority of amputees in developing nations encounter major c…