20,037 real projects from ISEF, the Canada-Wide Science Fair, JSHS and the Calgary Youth Science Fair — searchable by meaning, and filterable by fair, year, category and award.
JSHS · 2025
Anthraquinones are naturally occurring organic compounds with antibacterial, anticancer, and immunomodulatory properties, yet their current pharmaceutical use remains limited. This research…
ISEF · 2025
Energy: Sustainable Materials and Design
Borophene is a newly synthesized material that is considered superior in various properties. Due to the challenges of hydrogen storage and transportation, hydrogen energy has not fully devel…
ISEF · 2025
Chemistry
This project synthesis and design of a molecular encapsulating particle EC@ccdz, as a novel approach for screening diagnosis of lung cancer to reduce mortality rates and the complexity of ad…
ISEF · 2025
Chemistry
Signaling pathways of specific protein kinases are one of the main forms of intercellular communication. The information transfer is based on the chain of activation responses, often initiat…
ISEF · 2025
Environmental Engineering
Per- and polyfluoroalkyl substances (PFAS) have been widely used in various products such as non-stick cookware and fire-fighting form. Due to their non-degradable properties ascribed to the…
ISEF · 2025
Technology Enhances the Arts
Haptic feedback technology offers innovative ways for visually impaired individuals to interact with their surroundings. Current solutions, however, are often prohibitively expensive and lac…
ISEF · 2025
Animal Sciences
Purpose Dog barks and visual cues are main channels through which dogs communicate their emotional states, such as anger, sadness, and excitement. However, accurately interpreting these is a…
ISEF · 2025
Cellular and Molecular Biology
Skeletal muscle cells regulate and provide many bodily functions. Skeletal muscle cells support movement, posture, and temperature regulation. In addition, skeletal muscle triggers an immune…
ISEF · 2025
Physics and Astronomy
The high fuel consumption rates of heavy combination trucks are unsustainable and damaging to the environment. When travelling at the recommended speed on interstate highways, most of a truc…
ISEF · 2025
Robotics and Intelligent Machines
Speech disorders such as stuttering, articulation errors, and atypical vocal patterns affect millions of children worldwide, limiting communication and confidence. Traditional therapy, while…
CYSF · 2025
How do different leavening agents impact the height of vanilla cake?
ISEF · 2025
Robotics and Intelligent Machines
Ornithopters have never fully replicated the efficiency of birds, which rely on complex kinematics that integrate thrust, lift, drag, and weight to optimize flight efficiency (Landell-Mills,…
ISEF · 2025
Environmental Engineering
The ornamental stone industry is responsible for the production of granites and marbles, but not all extracted material is used, as waste is discarded into nature due to its lack of added va…
ISEF · 2025
Biochemistry
Cancer cells can develop chemoresistance, causing treatment failure in over 90% of metastatic cancer patients. GPX4 inhibitors are promising ferroptosis inducers for chemoresistant tumors bu…
ISEF · 2025
Translational Medical Science
Cancer remains one of the most significant global health challenges, with the c-MYC proto-oncogene implicated in over 50% of cases, particularly in solid tumors. When dysregulated, c-MYC pro…
ISEF · 2025
Cellular and Molecular Biology
Hypoxia is common in solid tumors. Hypoxia Inducible Factor 1 Alpha (Hif1a) is upregulated and stabilized under hypoxic conditions, leading to tumor growth. This experiment targets Hif1a bec…
JSHS · 2025
Purpose: The accumulation of advanced glycation end products (AGEs) and their interaction with the receptor for AGEs (RAGE) have been implicated in the progression of prostate cancer (PCa),…
ISEF · 2025
Translational Medical Science
Histone Lysine Demethylase 4 (KDM4) and Mammalian Bromodomain and Extra-Terminal Domain (BET) are proteins that are highly dysregulated in multiple kinds of cancers. This study researched th…
ISEF · 2025
Computational Biology and Bioinformatics
Diabetes significantly worsens breast cancer (BC) progression by enhancing pathological angiogenesis through metabolic stress, increasing mortality rates by up to 40%. As molecular factors a…
ISEF · 2025
Biomedical and Health Sciences
Cancer has remained the leading cause of death globally, with the mutation of the Tumor Suppressor Gene TP53 via DNMT1 methylation occurring in 50% of cases. Current epigenetic therapies mis…
ISEF · 2025
Earth and Environmental Sciences
Coral reef ecosystems are rapidly deteriorating as they endure global threats leading to negative economic impacts, loss of cultural understanding and a decrease in habitat and biodiversity.…
CYSF · 2025
I will be investigating the topic of how age affects taste bud sensitivity by testing various ages by on their sensitivity and preference to each of the different taste groups and analyzing…
ISEF · 2025
Physics and Astronomy
This study explores the dynamics of the restricted three-body problem within the field of celestial mechanics by utilizing Taylor integration via programming in the Julia language. This exte…
CYSF · 2025
A Research Initiative built around comprehending the correlation between Youth Psychological Traits such as Empathy, Moral Reasoning, Impulsivity and Social Vulnerability, to our Views and J…
ISEF · 2025
Biomedical and Health Sciences
Pulmonary hypertension (PH) is a pulmonary vascular disease exhibiting a high mean arterial pressure (25mmHg at rest). Cellular hyperproliferation contributes to vascular remodeling, leading…
ISEF · 2025
Behavioral and Social Sciences
The study of linguistics, specifically that of perception and production of non-native languages, helps researchers better understand language learning mechanisms. By utilizing uncommonly sp…
CYSF · 2025
Testing to see how temperature impacts the viscosity of different materials.
JSHS · 2025
Robles, B.S. In 2022, 2.3 million cases of breast cancer were diagnosed worldwide; approximately 17% were classified as triple-negative breast cancer (TNBC). TNBC is difficult to mitigate du…
ISEF · 2025
Cellular and Molecular Biology
In 2022, 2.3 million cases of breast cancer were diagnosed worldwide, with approximately 17% classified as triple-negative breast cancer (TNBC). TNBC is challenging to treat due to the absen…
ISEF · 2025
Chemistry
Heavy metal water contamination, specifically by hexavalent chromium (Cr(VI)), a carcinogenic byproduct of textile, rubber, and artificial fertilizer production, severely harms marine organi…