Mitochondria are highly dynamic organelles that interact with various cellular components, including the endoplasmic reticulum (ER). This essential interaction occurs through mitochondria-as…
Peripheral Arterial Disease (PAD) is caused by the blockage or narrowing of arteries supplying the lower extremities regions which affects approximately 10% of the U.Spopulation and is one o…
The detection of proteolytic activity in vitro is a promising field in understanding and identifying biological processes that occur within living cells. There is little research and experim…
Glioblastoma is a malignant brain tumor distinguished by intra-tumoral heterogeneity and inevitable recurrence. Residual tumor-initiating cells in the infiltrated normal brain parenchyma, te…
Obesity and diabetes are life-debilitating health conditions that may lead to life-long health complications. Energy homeostasis is tightly regulated, helping maintain food satiation and sat…
In an increasingly tumultuous and tense political and racial climate, there is new information in the concept of racial trauma. Racial trauma is a direct effect of personal experience or exp…
With the rapid rise of antibiotic resistance in bacteria, the fundamental need for new antimicrobial therapeutics is a pressing concern. In order to have an adequate arsenal to target antibi…
Congressional districts are often perceived as being biased towards specific parties or groups. Recently, due to major court cases the problem of gerrymandering has received much attention f…
Blood glucose (BG) control is important for all individuals, especially diabetics, to evaluate and manage their metabolic health. Poor BG control results in dysglycemia. Frequent exposure to…
Chronic Hepatitis Bvirus (HBV) infection affects 300 million people worldwide, with no existing cure. The first- line treatment is interferon (IFN), an antiviral cytokine. However, clinical…
Current Artificial Intelligence (AI) systems can learn arbitrarily complex patterns but struggle to generalize and adapt to new situations, making them unsuitable for real-world deployment.…
Obesity is a severe health problem predicted to affect one in two U.S. adults by 2030. Leptin, an adipocyte- derived satiety-inducing peptide hormone, plays a critical role in mediating food…
of Utah Liver cancer is the third leading cause of cancer deaths worldwide. In 2020, there were about 830,000 deaths due to liver cancer and over 900,000 new diagnoses. About 90% of all prim…
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with a significant genetic contribution. Studies have identified hundreds of genes with evidence of involvement in ASD when mu…
Neuroblastoma one of the most severe tumors in young children with nearly 500 new cases reported each year. Currently, the only treatments available for this cancer are chemotherapy and radi…
Wildfires pose severe health and ecological consequences. In 2021 alone, 58,968 wildfires burned 7.1 million acres across the United States. Large wildfires (> 300 acres) in the United State…
There is a common perception that political polarization is increasing in American society and the blame is often assigned to highly partisan traditional media (e.g., TV news channels) and t…
Ocean acidification and elevated temperatures are rising issues as they lead to substantial changes in the ocean’s chemistry and have adverse effects on the ecosystem of oceanic organisms. T…
Despite nearly 2 million people in the United States having an upper-arm amputation, 27- 56% of upper-body amputees use a prosthetic arm to regain limited mobility of their arm pre-amputatio…
Many water sources contain emerging contaminants that currently lack sufficient regulation but lead to debilitating health and environmental effects, yet current standard water treatment pro…
Larger sets of data and information in computational systems are oftentimes misinterpreted or tedious to analyze because of human error. Classical machine learning (ML) can be sufficient in…
Quantum computing is revolutionizing cryptography, but it will render the classical digital signature schemes such as ECDSA (Elliptic Curve Digital Signature Algorithm) insecure. Therefore,…
In mid-2022, a new outbreak of Mpox circulated the world—this time with high infectiousness and transmissibility. In just six months, 30,000 cases were reported. As we recovered from COVID-1…
A class of type II diabetes medication interacts with a nuclear receptor known as PPARγ. While these drugs are effective at managing type II diabetes, however, they have dangerous side effec…
Urine output is an important indicator of the level of renal impairment in patients. Accurately measuring urine output is critical in the treatment of hospitalized patients with renal injury…
Squamous Cell Carcinoma (SCC) is the second most common nonmelanoma skin cancer. If left untreated, SCC can be aggressive, with potential to deform adjacent tissue or metastasize. Most cases…
Infections with rabies virus (RABV) and related lyssaviruses are uniformly fatal once virus accesses the central nervous system (CNS). Current immunotherapies are thus focused on the early,…
Agroinfiltration, a simple and efficient method to transiently express recombinant proteins in plants using Agrobacterium bacteria, is a popular method for biological research. However, few…
Androgen insensitivity in PC-3, a variant of prostate cancer, has been recognized as highly lethal and drug-resistant due to its reduced dependency on substances that are commonly inhibited…
Probiotic Foods are known to have many health benefits such as bolstering intestinal health, reducing risk to many diseases, and reducing antibiotic resistance, to name a few. Because these…