AJAS Microbiology projects

Computational Discovery of Quorum Sensing Inhibitors Among Fda-Approved Drugs

Microbiology (inferred)

Curcumin and Salicylic Acid as Natural Alternative S. Epidermidis Treatment

Microbiology (inferred)

Over the last decade, methicillin-resistant S. aureus (MRSA) prevalence increased by nearly 35% worldwide. MRSA infections are most commonly found in hospitals, with the skin being the most…

Evaluation of a Bile Acid Antibiotic That Can Treat Superbug Bacterial Infection

Microbiology (inferred)

Antibiotics have revolutionized medicine, saving countless lives since the introduction of penicillin. However, antimicrobial resistance has challenged their efficacy, prompting ongoing effo…

Growth of S. Epidermidis After Treatments of Red Light, Chlorophyll, and Acetic Acid

Microbiology (inferred)

Infections caused by the bacteria Staphylococcus aureus are common and dangerous, and antibiotic treatments may not be available or appropriate in all cases. This creates the need for afford…

Magnesium Forms and L. Acidophilus Growth in Simulated Gi Conditions

Microbiology (inferred)

Despite numerous studies on the importance of magnesium intake, little is known about the variations between different forms of magnesium and their interactions with gut bacteria. Magnesium…

Silver-Doped Quantum Materials to Eradicate Gram-Positive and Gram-Negative Bacteria

Microbiology (inferred)

Antibiotic-resistant bacteria such as Methicillin-resistant Staphylococcus aureus (MRSA) and Salmonella Typhi can cause life-threatening illnesses in humans. The antimicrobial properties of…

Bile Acid-Derived Antibiotic via Dye Leakage Use Bacterial Membrane-Mimicking Lipid Vesicles

Microbiology (inferred)

Antibiotics have revolutionized medicine, saving millions of lives since the initial discovery of penicillin in the 1930s. Since then, numerous antibiotics have been developed to treat a var…

Developing Cost-Effective Alternative: Treating Small Intestinal Bacterial Overgrowth

Microbiology (inferred)

Small Intestinal Bacterial Overgrowth (SIBO) is a poorly understood disease characterized by the overgrowth of bacteria in the small intestine. The current treatment for SIBO is rifamycin an…

Functional Characterization of Bacteriophage Gene Product Toxic to Mycobacterium Smegmatis

Microbiology (inferred)

Antibiotic resistance is a critical global health challenge, with the UN estimating that drug-resistant infection deaths will surpass cancer deaths by 2050. Bacteriophages offer a potential…

Investigating Variations in E. Coli Post in Vivo Gut Colonization Model

Microbiology (inferred)

Pathogenic E. coli, particularly the globally prevalent sequence type 131 (ST131), poses a significant health threat, causing numerous infections annually. ST131 is an extended spectrum β-la…

Isolating, Screening, and Identifying Bacteria and Fungi for Antimicrobial Natural Products

Microbiology (inferred)

Mangrove ecosystems around the world have a notably high species diversity, especially due to their vast microbial communities. Those diverse communities are most commonly found packed withi…

Modeling Potential Impact of Global Warming on Soil Bacteria Composition

Microbiology (inferred)

Background: Soil microbes are essential for nutrient cycling, organic matter decomposition, and maintaining plant health. However, rising temperatures pose a threat to soil biodiversity. Thi…

Zingerone-Ampicillin Combination for Inhibition of Staphylococcus Epidermidis

Microbiology (inferred)

Infections caused by Staphylococcus epidermidis (S. epidermidis) often require medical treatment, and S. epidermidis is resistant to many antibiotics. This study explored the impact of zinge…

Antibiotic Resistance Genes Identified in Water Sources of Hot Springs

Microbiology (inferred)

Hot Springs, Arkansas is a tourist town known for its geothermal hot springs, which contain microbial thermophiles that thrive at high temperatures. These springs have several sources of wat…

Bacteria in Hospitals

Microbiology (inferred)

I chose this project because when I am older I want to work in the healthcare field. Specifically an OB nurse. So I thought about doing something related to what I want to do when I am older…

Characterization of a Bacteriophage Protein That Is Toxic to Mycobacterium Smegmatis

Microbiology (inferred)

Antibiotic resistance is one of the most pressing public health concerns of our time. Currently, antibiotic resistance causes nearly 3 million infections and over 35,000 deaths in the U.S an…

Home Remedies of the Apis Mellifera Kind vs Streptococcus

Microbiology (inferred)

In order to determine whether Apis mellifera home remedies were effective in preventing and shortening the time of Streptococcus salivarus, I tested raw natural honey, hydrogen peroxide, and…

Isolation of Antimicrobial Compounds from Soil Microorganisms with an Ichip Technique

Microbiology (inferred)

35,000 people die annually in the U.S. from antibiotic resistant infections (Antibiotics/Antimicrobial Resistance, 2021). Efficacy of antibiotics is endangered by rapid emergence of resistan…

Supplementing Antibiotics with Varying Sizes of Gold Nanoparticles on E. Coli

Microbiology (inferred)

Antibiotic resistance is a growing problem in medicine, leading to an urgency for developing alternatives to traditional antibiotics. Recent research has investigated the potential of gold n…

AJAS · 2022

Antimicrobial Recombinant Spider Silk

Microbiology

Surgical site infection (SSI) from sutures has become a major global health emergency as a result of the rise in antibiotic resistance. Methicillin-resistant S. aureus and other pathogenic s…

AJAS · 2022

Bacterial pathogens were found in the Lone Star Tick in Central Nebraska.

Microbiology

This study was performed due to my interest in outdoor activities. The goal was to determine the presence of local pathogens that could potentially affect people. I hypothesized that lone st…

AJAS · 2022

C. elegans nematodes are shown to have a long-lasting microbiome composition

Microbiology

C. elegans is a common model organism, as their translucent anatomy, ease of culture, and short life cycle make them an easily observable, low-maintenance subject for experimentation. With t…

AJAS · 2022

Cross-species transmission of D. melanogaster Nora virus in other species and geotaxis effect

Microbiology

The Nora virus, a virus that infects fruit flies, was known to infect the species, Drosophila melanogaster. My research showed the virus to infect two other Drosophila species from different…

AJAS · 2022

Finding and Analyzing New Target Genes for Treatment of Lung Adenocarcinoma using Bioinformatics

Microbiology

Lung adenocarcinoma (LUAD) accounts for forty percent of all lung cancer cases in the United States. Treatment currently focuses on surgery and chemotherapy, but survival rates remain lower…

AJAS · 2022

Gut bacteria can be engineered to potentially treat Crohn's disease

Microbiology

Because of the strong association between microbial imbalance, decreased short-chain fatty acid (SCFA) production, and Crohn’s disease (CD) onset, microbiota-targeting therapies are crucial…

AJAS · 2022

Surpassing Time Restraints: The Search for Viruses That Kill Many Bacteria

Microbiology

Mycobacteriophages are viruses that are parasitic to the fungus-like Mycobacterium, and with the recent increase in antibiotic resistance in these bacteria such as M. tuberculosis, more rese…

AJAS · 2022

The fungus Trametes versicolor can degrade Escherichia coli in water

Microbiology

Escherichia coli contamination is a major health concern that can cause adverse health effects like fever and gastrointestinal illness. White-rot fungi produce exoenzymes that degrade pollut…

AJAS · 2022

The SARS-COV-2 S-protein impacts cell survival via apoptosis, a programmed cell death pathway.

Microbiology

The current pandemic of novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) poses a severe global public health threat. Studying the molecular mechanisms of SARS-CoV-2 is critic…

AJAS · 2022

Towards a protein-based diagnostic that accurately measures anyone's ability to respond to COVID-19

Microbiology

Background. The protective effects of coronavirus vaccines rely on their ability to mount a long-term immune response; the initial response that results in immune memory relies on T cells an…

AJAS · 2022

Treatment of E. coli Biofilm Using Galla chinensis and Adjuvant Chemicals

Microbiology

Bacterial biofilms are present in about 60% of human infections, with those consisting of Gram-negative bacteria exhibiting particularly high resistance to antibiotics. To treat infections i…