ISEF · 2014
How Fast Is Fast?
Mathematics
My experiment consisted of testing the effectiveness of antacids in two different ways, and I also tested how long it remained effective. I started by testing the effectiveness by crushing o…
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ISEF · 2014
Hydrogen Sulfide Ameliorates Hearing Loss during Ischemic Stroke
Mathematics
Known as the third leading cause of death in the United States, cerebrovascular ischemic stroke leads to over 100,000 deaths per year. Furthermore, stroke causes long-term disabilities, one…
ISEF · 2014
Identification of Novel Broad-Spectrum Antimicrobial Compounds in Curcuma amada
Mathematics Fourth Award
Clostridium difficile and Methicillin-resistant Staphylococcus aureus (MRSA) have been the main source of nosocomial infections in North America since 2003. There is currently no effective a…
ISEF · 2014
Induced Pluripotent Stem Cell-Derived Cardiomyocytes as a Model for Ischemia Reperfusion Injury
Mathematics
Animals are currently used in most models for research. Although they have been a significant part of research it often takes many years for them to translate into clinical studies. Models u…
ISEF · 2014
INGAP Circles around Diabetes
Mathematics
Diabetes is a prevalent disease with serious complications. Current treatment involves repeated daily insulin injections, self monitoring blood tests and dietary management. A novel treatmen…
ISEF · 2014
Inhibiting the Growth of the Aedes aegypti Larvae on Used Car Tires Utilizing Baby Oil Capsules: Dengue Fever Primary Prevention
Mathematics
Used car tires are often stockpiled, due to lack of effective recycling systems, collecting water and providing a prolific breeding site for the Aedes aegypti mosquito, a vector for several…
ISEF · 2014
Inhibitory Effects of Allicin on Escherichia coli DH5(ALPHA) Growth
Mathematics
This project explores the effectiveness of allicin in Allium sativum (garlic) and Allium cepa (onion) in preventing the growth of Escherichia coli DH5a. The allicin in Allium sativum is one…
ISEF · 2014
Interactions of Bactericidal Essential Oils
Mathematics
The purpose of this study was to discover the most effective bactericidal essential oils, especially in combination, on Gram-positive and Gram-negative bacteria. BSL-1 microorganisms Escheri…
ISEF · 2014
Interfering with Glioblastoma Multiforme (GBM) Metabolism to Complement the Therapeutic Effects of Temozolomide
Mathematics
Glioblastoma multiforme (GBM), a serious form of brain cancer, has an average life expectancy of approximately 1.2 years. The current standard of care is treatment with a drug known as Temoz…
ISEF · 2014
Investigating the Effect of Polyhydroxylated Small-Gap Fullerene as an Antioxidant for Amyloidß-Induced Free Radicals in NT2 Cells
Mathematics Fourth Award
Alzheimer's Disease is currently an incurable disease that is growing over time. A current treatment-aim is to inhibit the neurotoxic effects of a protein peptide found in Alzheimer's diseas…
ISEF · 2014
Investigating the Opposing Roles of Oncoprotein gC1qR and Tumor Suppressive cC1qR as Mechanisms for Inhibiting Cancer Pathogenesis
Mathematics
Current cancer treatment methods remain flawed, oftentimes lacking tumor specificity and causing undesirable side effects. Consequently, elucidating the mechanisms behind tumorigenesis is an…
ISEF · 2014
Investigation of CD8 T Cell Dynamics in Pathogenic and Non-pathogenic SIV Infection
Mathematics
Sooty Mangabeys (SMs), natural hosts of SIV, maintain levels of CD4 T cells and do not progress to AIDS. Rhesus Macaques (RMs) model HIV infection in humans. The purpose of this data collect…
ISEF · 2014
Isothermal Nucleic Acid Amplification System for Point-of-Care HIV Diagnosis
Mathematics Second Award
Approximately 34 million people worldwide are infected with HIV, including 2.3 million children. To date, there is no accurate point-of-care HIV test for neonates or acutely infected adults.…
ISEF · 2014
Is There Gliosis in the Autistic Brain?, Year Two
Mathematics
Autism is a brain development disorder in which patients struggle with social interactions, verbal and non-verbal communication, and show restricted/repetitive behaviors. This study aims to…
ISEF · 2014
Is Working in Healthcare Unhealthy?
Mathematics
This project is testing for antibiotic-resistant strains of bacteria in health care workers. Healthcare workers inevitably have frequent contact with a variety of pathogens. this may make th…
ISEF · 2014
Kawakawa Extracts Demonstrate Anti-Inflammatory Activity
Mathematics
Kawakawa (Macropier excelsum), a plant native to New Zealand, is considered to be very significant to Maori (the indigenous people of New Zealand) as a key tool in rongoa (the holistic medic…
ISEF · 2014
Killed by Sweetness
Mathematics
Bacteria in the mouth if not controlled can lead to tooth decay. One cause of tooth decay is fermentation of sugars like glucose, fructose, and sucrose. Millions of dollars are spent yearly…
ISEF · 2014
Lactobacillus vs. Amoxicillin: Beneficial Bacteria as a Treatment for Sinus Infections
Mathematics
Lactobacillus is a beneficial bacteria that is naturally present in the human digestive tract. It is used in probiotics and kills harmful bacteria that are responsible for digestive problems…
ISEF · 2014
Let Food Be Your Medicine and Medicine Be Your Food
Mathematics
Providing organic, antimicrobial alternatives to pharmaceutically manufactured antibiotics is crucial in cases in which prescription drugs are not available or patients decline treatment due…
ISEF · 2014
Light It Up
Mathematics
This project is on the effects of Syntonic Light Therapy on peripheral vision. The basis for this research was to determine if certain wavelengths of light would change or affect peripheral…
ISEF · 2014
Lipoproteins as a Vehicle for Targeted and Selective Delivery of Hydrophobic Drugs to Cancer Cells
Mathematics
Thousands of oncologic patients and the increasing number of cancer deaths worldwide signalize an urgent need to develop new effective cancer treatments. An enhancement of the cancer treatme…
ISEF · 2014
Loss of TDP43 in Motor Neurons Leads to Deficits in Axonal RNAs in an Animal Model of ALS
Mathematics Third Award
Amyotrophic Lateral Sclerosis (ALS) is a lethal neurodegenerative disease that affects both the upper and lower motor neurons of the CNS. Mutations in TDP-43, a putative RNA binding protein,…
ISEF · 2014
Man and Medical Machine: For Better or Worse
Mathematics
The purpose of this experiment is to determine how the da Vinci robot compares to other surgical methods. IRB approval was obtained through the major medical hospital. Using the data bank re…
ISEF · 2014
Medicinal Properties of Ocimum basilicum and Azadirachta indica
Mathematics
In the past, Ocimum basilicum (Basil) and Azadirachta indica (Neem) have been considered medicinal plants. With the need for new antibiotics and bacteria constantly evolving and resistant, B…
ISEF · 2014
Mela NO MORE: Creating Novel and Potent siRNA-based Biotherapies for the Treatment of Melanoma
Mathematics Second Award
The prevalence of tanning and UV-overexposing activities continues to enthrone skin cancers as the most common type of cancer affecting humans. The deadliest and most aggressive form of thes…
ISEF · 2014
Microevolution of Bacillus subtilis in Response to Isopropanol Alcohol Stress
Mathematics
From the moment we discovered the existence of germs, we have been trying to kill them. And from that moment, they have been adapting. Even now, as we introduce ever increasingly effective a…
ISEF · 2014
Molecular Charazterization and Screening of Metabolic Diseases Ornithine Transcarbomylase Deficiency (OTC) and Citrullinemia (CIT) among Puerto Ricans
Mathematics
Newborn screening is a vital process that defines the course that a baby’s life could take. Identifying metabolic diseases at early stages gives the opportunity of early treatment, making th…
ISEF · 2014
Moringa Power: Old or New?
Mathematics
For centuries, man has turned to plants to provide not only sustenance but also medicine. The purpose of this project is to isolate and identify the compound(s) responsible for the antibacte…
ISEF · 2014
MUC1 as a Biomarker for TGF-ß1 Inhibition: Investigating the Role of MUC1 in the Switch of TGF-ß1 Function from a Tumor Suppressor to a Tumor Promoter in Pancreatic Ductal Adenocarcinoma
Mathematics Second Award
With a 5-year survival rate of only 6%, pancreatic ductal adenocarcinoma (PDA) is the 4th leading cause of cancer related deaths in the United States. Transforming Growth Factor-ß1 (TGF-ß1),…
ISEF · 2014
Multicomponent Drug Delivery Systems Based on PLCL Nanofibers and Modified Gold Nanoparticles in Cancer Treatment
Mathematics Fourth Award
The idea of the project is the design of advanced systems potentially useful in targeted cancer therapy and neurosurgery. In my project I have focused on composites of modified gold nanopart…