Browse real student projects, abstracts, and awards.
ISEF · 2023
Computational Biology and Bioinformatics
Over 50 million Americans have an Autoimmune Disease (AD). Diagnosis of symptoms is challenging and the available treatments are invasive and costly. As chronic diseases, ADs often significa…
ISEF · 2023
Computational Biology and Bioinformatics
Deep brain stimulation (DBS) is a novel therapy for Parkinson's disease, in which an electrode is surgically implanted into the patient's brain and remotely controlled to send an electrical…
ISEF · 2023
Computational Biology and Bioinformatics Fourth Award
Determining neuronal identity in imaging data is an essential task in neuroscience, facilitating the comparison of neuronal activity across organisms. Cross-organism comparison, in turn, ena…
ISEF · 2023
Computational Biology and Bioinformatics
Animal venoms consist of toxin peptides and proteins, and drugs derived from venoms are unique in their ability to interfere with key biological processes in the body, such as blood clotting…
ISEF · 2023
Computational Biology and Bioinformatics Third Award
Over the last few decades, many breast cancer patients have become disease-free due to the advancements in detection, diagnosis, and treatment. However, cancer can come back for almost 30% o…
ISEF · 2023
Computational Biology and Bioinformatics
By 2040, the global cancer burden will rise to 30 million new cases annually, with the greatest increases affecting low-to-middle-income countries. Current diagnosis methods, such as physica…
ISEF · 2023
Computational Biology and Bioinformatics Fourth Award
Dysregulation of protein phosphorylation during cellular development and signal transduction is associated with a myriad of human cancers, Parkinson’s Disease, and Alzheimer’s Disease. Under…
ISEF · 2023
Computational Biology and Bioinformatics Third Award
Miniature-sized shape morphing Microbots are increasingly gaining momentum in several medical applications, including targeted drug delivery and the removal of blood clots. There has been si…
ISEF · 2023
Computational Biology and Bioinformatics First Award
In mid-2022, Mpox reemerged with heightened infectivity and transmissibility, causing 30,000 cases in just six months. As we recovered from COVID-19, fear of another pandemic heightened. Two…
ISEF · 2023
Computational Biology and Bioinformatics
As global life expectancy improves, the population of the elderly, persons that are aged 65 years and older, is steadily increasing as well. However, with aging populations a greater prevale…
ISEF · 2023
Computational Biology and Bioinformatics
Cocaine addiction is an issue that affects more than 5 million people in America per year. Despite past progress in cocaine addiction research, there are many specific questions left unanswe…
ISEF · 2023
Computational Biology and Bioinformatics
Hyperinflammation is the most severe clinical phase of Covid-19 disease and is characterized by high blood pressure in the lungs, which facilitates microthrombus formation, eventually leadin…
ISEF · 2023
Computational Biology and Bioinformatics
Zooxanthellae expulsion (Coral bleaching) is a significant concern for biodiversity and economic prosperity, considering mass bleaching has now occurred in every region worldwide. This study…
ISEF · 2023
Computational Biology and Bioinformatics
The Human Immunodeficiency Virus (HIV-1) is a globally prevalent virus that attacks CD4 cells in the human immune system, decreasing the quality and length of life for those affected. The mo…
ISEF · 2023
Computational Biology and Bioinformatics
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease that obstructs airflow and causes difficulty breathing. It is responsible for approximately 3.2 million de…
ISEF · 2023
Computational Biology and Bioinformatics
Metabolism forms the foundation of understanding how cellular processes work; however, not all reactions within a metabolic network are fully understood. Some specific metabolic pathways in…
ISEF · 2023
Computational Biology and Bioinformatics
Pulmonary fibrosis occurs when lung tissue becomes damaged or scarred and can be progressive in nature, impacting an individual’s ability to breathe. Idiopathic pulmonary fibrosis (IPF) and…
ISEF · 2023
Computational Biology and Bioinformatics
With a prevalence of 2-8% of the world population, the insidious disease Fibromyalgia(FM) posses a threat. Fibromyalgia is a chronic-pain disorder characterized by widespread musculoskeletal…
ISEF · 2023
Computational Biology and Bioinformatics Fourth Award
Cardiovascular disease (CVD) is the leading cause of human death, accounting for 17.8 million deaths in the past year. CVD causes dysfunction in blood proteins and cells. These dysfunctions…
ISEF · 2023
Computational Biology and Bioinformatics
Acute Kidney Injury (AKI) is a major clinical complication with an incidence of 50% among critical care patients and an observed in-hospital mortality of 62%. The early identification of pat…
ISEF · 2023
Computational Biology and Bioinformatics
The early division of nuclei in a Drosophila embryo is composed of eight nuclear divisions, or cycles, producing a total of 256 nuclei by the eighth cycle. The nuclei start in the center of…
ISEF · 2023
Computational Biology and Bioinformatics Second Award
Breast Cancer (BC) is the most commonly diagnosed cancer and is a significant cause of death worldwide, affecting around 2.3 million women annually. Triple-negative breast cancer (TNBC) is a…
ISEF · 2023
Computational Biology and Bioinformatics
In past work, invasive implants that implement a process called deep brain stimulation (DBS) in order to regenerate sight for the visually impaired have been investigated. DBS is a surgical…
ISEF · 2023
Computational Biology and Bioinformatics
Colorectal cancer (CRC) has multiple subtypes, and it may take patients weeks to find out which subtype they have. The goal of this research is to use gene expression data to determine poten…
ISEF · 2023
Computational Biology and Bioinformatics
Hepatocyte growth factor receptor (HGFR or c-MET) is a receptor tyrosine kinase that has been found to be linked to cancer, with malignant mutations causing tumor growth, angiogenesis, and m…
ISEF · 2023
Computational Biology and Bioinformatics
Hi-C, a chromosome conformation capture-based method, allows researchers to interrogate chromatin interactions between any two genomic loci in a bulk of cells and study the spatial arrangeme…
ISEF · 2023
Computational Biology and Bioinformatics Third Award
Microbial DNA is a novel analyte for early cancer detection. Although recent studies have found distinct communities of bacteria and fungi between tumor types, they have not investigated mic…
ISEF · 2023
Computational Biology and Bioinformatics
The inefficient treatment of thousands of diseases contributes to the need for a quick and cost-efficient alternative to current drug discovery methods. Drug development is extremely time-co…
ISEF · 2023
Computational Biology and Bioinformatics
Eye diseases can potentially cause blindness in patients. Cataracts are the leading cause of blindness, accounting for over 51% of blindness worldwide. Glaucoma and diabetic retinopathy foll…
ISEF · 2023
Computational Biology and Bioinformatics
Have you ever wondered where your fingerprints come from? The purpose of this project was to determine if fingerprints are genetically inherited through biological factors or relations and o…