Browse real student projects, abstracts, and awards.
ISEF · 2020
Computational Biology and Bioinformatics
Epilepsy is a chronic brain disorder impacting over 65 million people globally. Each year, >100000 patients die from Sudden Unexpected Death in Epilepsy (SUDEP), many from fatal falls. A rel…
ISEF · 2020
Computational Biology and Bioinformatics
Disease-disease correlations lend to improved treatment modalities, however, current disease-disease correlation databases fail to include poorly-studied diseases. Craniosynostosis, despite…
ISEF · 2020
Computational Biology and Bioinformatics
Gene expression is regulated by proteins known as transcription factors, which bind to specific DNA sequences called enhancers. Enhancers activate nearby genes, but there is still a limited…
ISEF · 2020
Computational Biology and Bioinformatics
As pollution levels rise, the relationship between pollutant degrading proteins across various organisms is vital to create a synthetic microbe that mitigates substance toxicity. To understa…
ISEF · 2020
Computational Biology and Bioinformatics
Dengue Fever is the most rapidly spreading mosquito-borne disease, with more than 25,000 deaths annually. To date, no vaccine has been developed for Dengue Fever due to the existence of four…
ISEF · 2020
Computational Biology and Bioinformatics
Acute Myeloid Leukemia (AML) is a deadly blood cancer in which abnormal blast cells crowd out healthy blood cells in bone marrow. Although AML is the most common adult leukemia, its survival…
ISEF · 2020
Computational Biology and Bioinformatics
Deep Neural Networks (DNNs) have successfully demonstrated superior overall performance in many image classification and recognition tasks on H&E histology images. Reported studies typically…
ISEF · 2020
Computational Biology and Bioinformatics
Artificial intelligence has been used to identify cancer types with high accuracy, but despite this, we see increased death rates in cancer. Even though cancer is a complex and extremely het…
ISEF · 2020
Computational Biology and Bioinformatics
In 2015, 13,000 Louisiana residents died of heart disease. Due to expensive cost of ECG analysis, underrepresented community people cannot get medical supports. There are challenges on medic…
ISEF · 2020
Computational Biology and Bioinformatics
[Problem] For individuals with hearing loss, distinguishing between various voices in noisy environments is difficult. Current hearing aids are unable to identify and attenuate background vo…
ISEF · 2020
Computational Biology and Bioinformatics
Cancer is something we hear in our everyday lives, it takes friends and loved ones and there seems like there is no help for them, especially when the treatment does not work. Through this p…
ISEF · 2020
Computational Biology and Bioinformatics
The student researcher tested for correlation between protein type and fatality rate in Zaire ebolavirus, hypothesizing that there is a significant difference in the fatality rates due to pr…
ISEF · 2020
Computational Biology and Bioinformatics
In our project, we sought to use machine learning to generate new lead molecules and expedite drug discovery. Lead molecules are molecules with an affinity for inhibiting the target protein,…
ISEF · 2020
Computational Biology and Bioinformatics
Cardiovascular malformations are the most common type of birth defects. Congential HeartDisease occurs in approximately 1% of all births globally and has a 48.1% infant mortality rate. Given…
ISEF · 2020
Computational Biology and Bioinformatics
Comparison of methods used to diagnose Alzheimer’s Disease (AD) via imaging, mental, and genetic data remains an open area of investigation. In this investigation, it was hypothesized that a…
ISEF · 2020
Computational Biology and Bioinformatics
Major depressive disorder (MDD) is a debilitating illness, and antidepressant treatment often yields inadequate response rates. It is not currently understood why antidepressant response rat…
ISEF · 2020
Computational Biology and Bioinformatics
The treatment of chronic wounds has long been a challenge to wound care professionals and presents a substantial economic burden to healthcare systems globally. Over $50 billion is spent on…
ISEF · 2020
Computational Biology and Bioinformatics
Detecting Alzheimer’s Disease (AD) at the earliest possible stage is key in advancing AD prevention and treatment but is challenged by confounders with the normal aging processes in addition…
ISEF · 2020
Computational Biology and Bioinformatics
Authors, Genes, Diseases, and Drugs in a Network (GADDNET) is a web-based platform that connects researchers and institutions via the genes and diseases they study. GADDNET can help research…
ISEF · 2020
Computational Biology and Bioinformatics
Cancer is a leading cause of death worldwide. Because the organ and cell type that generated the tumor determine a patient’s response to therapies, quick and accurate identification of the p…
ISEF · 2020
Computational Biology and Bioinformatics
The sequences of most proteins are inferred from the longest open reading frame (ORF) found in their parent mRNA. While the rule is simple and convenient, it does not model the underlying bi…
ISEF · 2020
Computational Biology and Bioinformatics
This investigation researches if using amino acids instead of nitrogenous bases in bacterial data storage systems protects against the corruption of the stored data due to mutations. The hyp…
ISEF · 2020
Computational Biology and Bioinformatics
Antimicrobial peptides (AMPs) are a growing field of therapeutics with lower risks of antimicrobial resistance compared to conventional antibiotics. However, experimentally testing peptides…
ISEF · 2020
Computational Biology and Bioinformatics
2 statistically likely, novel drug candidates for solute transporter protein member 5, SLC5, were identified in this study. Dysfunction of a roundworm orthologue of SLC5, sulp-5, was linked…
ISEF · 2020
Computational Biology and Bioinformatics
According to the FDA, approximately 1.3 million people are injured due to medicine errors annually in the United States. A large percentage of these people are the elderly and people with mu…
ISEF · 2020
Computational Biology and Bioinformatics
Parkinson’s Disease (PD) is a disorder that inhibits the dopaminergic neurons in the brain. Currently, there is no accurate non-clinical way to diagnose PD, forcing medical professionals to…
ISEF · 2020
Computational Biology and Bioinformatics
New species of bacteria are being discovered on a daily basis. Fast detection and risk characterization are vital for taking proper action. Current techniques and methods used for microbial…
ISEF · 2020
Computational Biology and Bioinformatics
Approximately 55,000 patients are treated daily in ICUs within the U.S., most of whom are extremely sick and require rapid clinical decision-making. However, copious patient data engenders i…
ISEF · 2020
Computational Biology and Bioinformatics
I set out to find the similarities between different aggregating proteins’ amino acid sequences and 3D conformations in neurodegenerative diseases (NDDs) using computational methods. Using t…
ISEF · 2020
Computational Biology and Bioinformatics
Models of metastasis-free survival based on microarray gene expression can be powerful tools for clinicians and have broad applications in risk quantification, genetic research, and palliati…