Browse real student projects, abstracts, and awards.
ISEF · 2019
Computational Biology and Bioinformatics
Computational modeling offers a powerful method for studying cause-effect relationships in biology. This is immensely valuable for creating synthetic biomimicry structures. Mimosa pudica is…
ISEF · 2019
Computational Biology and Bioinformatics Third Award
Plant field testing proves often a long and costly process crucial to the development of efficient agricultural techniques. We aimed to create a plant topology simulator that presents a sign…
ISEF · 2019
Computational Biology and Bioinformatics
The 2.4-fold increase in thyroid cancer over recent decades and variation across regions indicate that environmental factors may be influencers, including I-131 released during nuclear testi…
ISEF · 2019
Computational Biology and Bioinformatics
Antibiotics can be used to cure bacterial infections. Antibiotics target various structures and processes within the cell such as protein synthesis, cell membrane integrity and cell wall syn…
ISEF · 2019
Computational Biology and Bioinformatics Third Award
A plummet in the research productivity of drug discovery has been observed in recent decades, with higher costs, longer timelines, and lower success rates of drug candidates in clinical tria…
ISEF · 2019
Computational Biology and Bioinformatics
Around the globe, G6PD enzyme deficiency is one of the widely-encountered diseases. There are more than 140 variants but the Mediterranean variant is commonly seen in the world. Therefore, t…
ISEF · 2019
Computational Biology and Bioinformatics
Approximately 20,000 different human proteins exist to perform specific tasks within a cell’s organelles focused on building, repairing, and giving signals needed for the body to survive. Ho…
ISEF · 2019
Computational Biology and Bioinformatics
Precision medicine, or personalized medicine, is the most promising direction for treating complex diseases, such as cancer. The deadliest solid cancer, Pancreatic Ductal Adenocarcinoma (PDA…
ISEF · 2019
Computational Biology and Bioinformatics
Dengue Fever is a debilitating viral disease of the tropics, transmitted by female Aedes mosquitoes, causing sudden fever, acute pains in the joints and hemorrhaging. The World Health Organi…
ISEF · 2019
Computational Biology and Bioinformatics
The accurate age estimation is a substantial part of the integral biological profile, but quite complex in cases of unidentified decomposed and skeletonized human remains, especially in adul…
ISEF · 2019
Computational Biology and Bioinformatics
With increasing interest in using fMRI and functional connectivity networks to understand and diagnose neurodegeneration, advanced method for image processing are necessary to produce highly…
ISEF · 2019
Computational Biology and Bioinformatics
Spatiotemporal modelling is important in understanding communicable disease progression dynamics and evaluating public health intervention strategies. However, existing spatiotemporal models…
ISEF · 2019
Computational Biology and Bioinformatics Third Award
According to UNICEF, Kenya has a very high prevalence of child mortality rate which is approximately 49/1000 live births. In 2017 Kenya had an estimated 502,860 children who had missed the r…
ISEF · 2019
Computational Biology and Bioinformatics
Transcription is the first, decisive phase of the genome expression. Genome transcription (when, where and how) is regulated by RNA polymerases, transcription factors and promoters. Protein…
ISEF · 2019
Computational Biology and Bioinformatics
In brain research, an important step after staining and imaging the different brain cells is their phenotyping. In this research, we work with patches of images, taken with CLARITY and aim t…
ISEF · 2019
Computational Biology and Bioinformatics Fourth Award
MicroRNAs (miRNAs) are small noncoding RNA molecules that are implicated in many gene expression pathways. Because they can degrade genes before translation, they have been extensively resea…
ISEF · 2019
Computational Biology and Bioinformatics
Time resolved X-ray crystallography produces molecular movies of proteins at femtosecond resolution. The elucidation of an enzyme’s structural dynamics during its catalysis has major implica…
ISEF · 2019
Computational Biology and Bioinformatics
EEG (electroencephalogram) based identification systems have a myriad of applications ranging anywhere from scalable EEG systems for disease diagnostics, anti-epileptic drug administration,…
ISEF · 2019
Computational Biology and Bioinformatics
Artificial Intelligence (AI) is the science of creating machines that can perform tasks which normally require human abilities (e.g. visual perception, speech recognition, decision-making).…
ISEF · 2019
Computational Biology and Bioinformatics
Amyloid fibrils are small or slender fibers that can be found all around the human body and are formed by misfolded proteins. These fibers are resistant to degradation and can cause many dis…
ISEF · 2019
Computational Biology and Bioinformatics Third Award
Studying B cell receptor (BCR) binding is crucial for understanding how the human adaptive immune system attacks cancer cells – information that can translate into targeted and more efficaci…
ISEF · 2019
Computational Biology and Bioinformatics Fourth Award
DNA-binding proteins play an especially important role in regulating gene expression. These proteins called transcription factors (TFs) recognize and bind to DNA-sequences called DNA motifs,…
ISEF · 2019
Computational Biology and Bioinformatics
Antimicrobial peptides have a broad spectrum of antimicrobial activities against bacteria, fungi, and even viruses, and there have been over 5000 AMP’s discovered. Individual peptides can be…
ISEF · 2019
Computational Biology and Bioinformatics
Since the discovery of radiation, scientists have endeavored to predict and understand the effects of radioactive materials in humans, which can cause serious ailments. The International Com…
ISEF · 2019
Computational Biology and Bioinformatics
Transcriptional pausing, the inhibition of RNA polymerase (RNAP) elongation during transcription, is a vital regulator of DNA transcription that offers increased control over gene expression…
ISEF · 2019
Computational Biology and Bioinformatics Fourth Award
Acute cardiac arrhythmias are the No. 1 killer in industrialized countries; the mechanisms behind the onset and electrical dynamics are poorly understood, and mathematical modeling is limite…
ISEF · 2019
Computational Biology and Bioinformatics
Diabetes affects 30 million Americans, and costs $300 billion a year. The first regimen prescribed to new patients is usually metformin: it is very effective at reducing the level of sugar i…
ISEF · 2019
Computational Biology and Bioinformatics
The understanding of genetic mutations and their effects is the foundation of personalized medicine. Currently, this interpretation is time-consuming, costly, and susceptible to bias, involv…
ISEF · 2019
Computational Biology and Bioinformatics
When conducting a study using fMRI, it is often beneficial to be able to track the eyes of participants, especially for experiments that require visual fixation. One method of achieving this…
ISEF · 2019
Computational Biology and Bioinformatics
Purpose: The purpose of this experiment is to use computational methods to dock compounds onto a Zika virus protease and find stable inhibitors, as indicated by a low binding and interaction…