Computational Biology and Bioinformatics
The pandemic brought about by Covid-19 has greatly disrupted the world. The virus has different mutations that can be seen in the population, but there are also many mutations that exist wit…
Computational Biology and Bioinformatics
When exposed to antibiotics for long enough, a bacterial population can evolve to become resistant. This prompts the creation of innovative therapeutics such as bacteriophage therapy. 'Phage…
Computational Biology and Bioinformatics
Protein-protein interactions guide essential life processes, including DNA repair. Nucleolin has many roles, but few efforts have been made to fully characterize its role in DNA repair. In t…
Computational Biology and Bioinformatics
Infectious diseases are a leading cause of mortality worldwide. Among the major pathogens, SARS-CoV-2 is a coronavirus causing the current COVID-19 pandemic. MERS-CoV and SARS-CoV also belon…
Computational Biology and Bioinformatics
Isoniazid (INH) is a ?rst line drug for the treatment of Tuberculosis, a disease that causes 1.5 million deaths per year. This drug has high e?cacy in TB-treatment, but can also lead to live…
Computational Biology and Bioinformatics
Third Award
Around 3.8 million women in the US are diagnosed with breast cancer. In terms of the survival rate, late or misclassified diagnosis decreases an individual’s chance of survival from 90% to j…
Computational Biology and Bioinformatics
Third Award
Features with rare states, such as rare genetic variants and low frequency amino acid mismatches, pose a surrounding their role in predicting outcomes such as disease phenotype. Bins of rare…
Computational Biology and Bioinformatics
First Award
Replication errors represent two-thirds of cancer mutations. A novel replication error subset, recurrent repeat contractions (rRCs), lack systematic examination in cancers due to complex amp…
Computational Biology and Bioinformatics
Third Award
The speed of ribosome movement along an mRNA transcript is a critical determinant of protein synthesis. Ribosome pause sites, or regions along an mRNA transcript where translating ribosomes…
Computational Biology and Bioinformatics
Motor neurons are the essential cells connecting the brain and muscles, translating our thoughts and needs into actions and response. Here, we analyze a previously published dataset to explo…
Computational Biology and Bioinformatics
The purpose of this experiment is to determine the relationship of breastfeeding and other social and economic factors to infant mortality on the Louisiana and national level. The researcher…
Computational Biology and Bioinformatics
Each year, over two million people globally are afflicted by potentially life-threatening antibiotic-resistant infections, and many scientists believe that antibiotic-resistant superbugs may…
Computational Biology and Bioinformatics
Fourth Award
Cancer is one of the deadliest illnesses in the world, and to find a cure for cancer, information must be obtained on the human body’s response to tumors. The purpose of this study was to id…
Computational Biology and Bioinformatics
Cancer metastasis poses a significant threat to global public health, accounting for an estimated 90% of cancer-related deaths, due to a lack of effective anti-metastatic agents. The overexp…
Computational Biology and Bioinformatics
As burgeoning crises have exposed failures of the drug discovery cycle - an inability to quickly and effectively develop new drugs - artificial intelligence-based drug repositioning models a…