38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2014
Computational Biology and Bioinformatics
Neuroblastoma is an aggressive pediatric cancer, with two thirds of all cases found in children ages five or younger. Current drugs cause adverse side effects which greatly affects the devel…
ISEF · 2014
Computational Biology and Bioinformatics
Chloramines have been used to disinfect potable water because they do not product carcinogenic DBP’s like traditional free chlorine. However, chloramines have been linked with lead leaching…
ISEF · 2014
Computational Biology and Bioinformatics Second Award
One in eight women will be diagnosed with a form of noninvasive Breast cancer during her lifetime. NEK2 is a highly-expressed gene in Breast cancer. The objective was to determine the role N…
ISEF · 2014
Computational Biology and Bioinformatics
The adult muscle has stem cells called satellite cells. Those cells are quiescent in a normal situation and they get activated after injury. The most important function of satellite cells is…
ISEF · 2014
Computational Biology and Bioinformatics
Cell culture is challenging due to the use of medium components such as fetal bovine serum and human serum, risk of transmission of microbial disease, allergies, and ethical issues. Thus, id…
ISEF · 2014
Computational Biology and Bioinformatics
This experiment analyzed the effects of solute concentration on the optical rotation of various chiral molecules by building a polarimeter to measure their angle of rotation and comparing th…
ISEF · 2014
Computational Biology and Bioinformatics
Eye-color genotypes are good predictors of eye-color phenotypes. The purpose of this project was to go the other direction and see if eye-color genotypes could be predicted based on eye-colo…
ISEF · 2014
Computational Biology and Bioinformatics
New evidences have revealed that the protozoan parasite Plasmodium falciparum uses a communication net based on the releasing extracellular vesicles from infected red blood cells. The conten…
ISEF · 2014
Computational Biology and Bioinformatics
Virus production is a limiting factor in fields that utilize viral platforms, including the fields of vaccinology, oncolytic virology, and gene therapy. Previous research has suggested that…
ISEF · 2014
Computational Biology and Bioinformatics
The purpose of this study was to screen several VHH nanobodies for effective intracellular binding to a-Synuclein (Syn), whose aggregation is associated with Parkinson’s disease. Previously,…
ISEF · 2014
Computational Biology and Bioinformatics Fourth Award
Damage to the heart muscle has long been considered irreparable and an indicator of future heart failure. When damaged, the heart forms a scar-like tissue that develops over regions of damag…
ISEF · 2014
Computational Biology and Bioinformatics
Bipolar disorder is a psychiatric disorder with phases of mania and depression. Past studies have implicated a relationship between bipolar disorder and NMDA receptor which is a glutamate re…
ISEF · 2014
Computational Biology and Bioinformatics
Cancer cells express surface proteins when they are formed, and among the proteins is MICA. MICA is recognized by human immune system such as NK cell, and NK cells secrete cytokines to remov…
ISEF · 2014
Computational Biology and Bioinformatics
The purpose of “Stay Home or Go Global - Local Versus Imported Fruit?” is to study what pesticides we may be eating and which fruits might be the worst ones. Pesticides can be fungicides or…
ISEF · 2014
Computational Biology and Bioinformatics Second Award
The fabrication of laser grade ceramics must be improved to achieve better reproducibility of high quality yields, requiring a control of the bulk stoichiometry beyond that of current analyt…
ISEF · 2014
Computational Biology and Bioinformatics
Malonyl-CoA:ACP Transacylase (MCAT) is a mitochondrial enzyme needed for the functionality of pyruvate dehydrogenase (PDH). PDH is known to play a critical role in a tumor suppressor network…
ISEF · 2014
Computational Biology and Bioinformatics First Award
Monosodium Glutamate (MSG) is one of the most commonly used spices for taste enhancement. Research has shown that people are sensitive to MSG and that all organs of the body contain glutamat…
ISEF · 2014
Computational Biology and Bioinformatics Second Award
Glioblastoma Multiforme is the most frequent and devastating malignant brain tumor among adults with an average life expectancy of one year after diagnosis. This is partly due to its multi-d…
ISEF · 2014
Computational Biology and Bioinformatics
Long non-coding RNAs (lncRNA) could become a revolutionary treatment for people with muscle ailments if they could be inserted into the muscle stem cells (or myoblasts) to control their prol…
ISEF · 2014
Computational Biology and Bioinformatics
G-protein Coupled Receptor 83 (GPR83) is a constitutively active orphan GPCR for which the ligand and molecular signaling pathways have yet to be fully characterized. Studies have shown that…
ISEF · 2014
Computational Biology and Bioinformatics
Sphingosine 1-phosphate (S1P) is a bioactive signaling sphingolipid produced by red blood cells and activated platelets. It is a ligand for 5 known G-protein coupled receptors (S1P 1-5) and…
ISEF · 2014
Computational Biology and Bioinformatics Third Award
Carrageenans are linear sulfated polysaccharides derived from red seaweeds that are popularly used in the food industry to gel, thicken and stabilize properties in certain foods, but their u…
ISEF · 2014
Computational Biology and Bioinformatics
Raman Spectroscopy and Surface Enhanced Raman Spectroscopy are important methods for both chemical and biochemical scientific research. The main purpose of my investigation was to increase t…
ISEF · 2014
Computational Biology and Bioinformatics
Many investigations have been conducted for years. While these investigations have been focusing on plant derived substances, there has been few studies focusing on animal derived organic su…
ISEF · 2014
Computational Biology and Bioinformatics
Researchers have recently found that the immune system of purple sea urchins is more diverse than previously believed. The diversity within the purple sea urchin immune system is derived fro…
ISEF · 2014
Computational Biology and Bioinformatics
The FOXP3 gene on the X-chromosome is responsible for the development and function of regulatory T cells. Our previous studies found that FOXP3 also behaves as an X-linked tumor suppressor i…
ISEF · 2014
Computational Biology and Bioinformatics Fourth Award
Bacteriocins are proteins that are toxic to bacteria, yet are made by them. These proteins may provide an alternative to traditional antibiotics but synthesizing them using recombinant metho…
ISEF · 2014
Computational Biology and Bioinformatics Fourth Award
True slime molds exhibit memory and navigation that may resemble the precursors to functions performed by our complex cognition networks. Physarum polycephalum has been shown to use its trai…
ISEF · 2014
Computational Biology and Bioinformatics
The human syndrome Xeroderma Pigmentosum (XP) is a rare genetic disease characterized by high sensitivity to sunlight, and, in some cases, early aging and neurodegeneration. Defects on eight…
ISEF · 2014
Computational Biology and Bioinformatics
The purpose of this experiment was to determine the effects of triclosan on the muscle functioning of a Pomacea diffusa snail. Triclosan is an antibacterial chemical found in consumer produc…