Browse real student projects, abstracts, and awards.
ISEF · 2014
Computational Biology and Bioinformatics
Long non-coding RNAs (lncRNA) could become a revolutionary treatment for people with muscle ailments if they could be inserted into the muscle stem cells (or myoblasts) to control their prol…
ISEF · 2014
Computational Biology and Bioinformatics
G-protein Coupled Receptor 83 (GPR83) is a constitutively active orphan GPCR for which the ligand and molecular signaling pathways have yet to be fully characterized. Studies have shown that…
ISEF · 2014
Computational Biology and Bioinformatics
Sphingosine 1-phosphate (S1P) is a bioactive signaling sphingolipid produced by red blood cells and activated platelets. It is a ligand for 5 known G-protein coupled receptors (S1P 1-5) and…
ISEF · 2014
Computational Biology and Bioinformatics Third Award
Carrageenans are linear sulfated polysaccharides derived from red seaweeds that are popularly used in the food industry to gel, thicken and stabilize properties in certain foods, but their u…
ISEF · 2014
Computational Biology and Bioinformatics
Raman Spectroscopy and Surface Enhanced Raman Spectroscopy are important methods for both chemical and biochemical scientific research. The main purpose of my investigation was to increase t…
ISEF · 2014
Computational Biology and Bioinformatics
Many investigations have been conducted for years. While these investigations have been focusing on plant derived substances, there has been few studies focusing on animal derived organic su…
ISEF · 2014
Computational Biology and Bioinformatics
Researchers have recently found that the immune system of purple sea urchins is more diverse than previously believed. The diversity within the purple sea urchin immune system is derived fro…
ISEF · 2014
Computational Biology and Bioinformatics
The FOXP3 gene on the X-chromosome is responsible for the development and function of regulatory T cells. Our previous studies found that FOXP3 also behaves as an X-linked tumor suppressor i…
ISEF · 2014
Computational Biology and Bioinformatics Fourth Award
Bacteriocins are proteins that are toxic to bacteria, yet are made by them. These proteins may provide an alternative to traditional antibiotics but synthesizing them using recombinant metho…
ISEF · 2014
Computational Biology and Bioinformatics Fourth Award
True slime molds exhibit memory and navigation that may resemble the precursors to functions performed by our complex cognition networks. Physarum polycephalum has been shown to use its trai…
ISEF · 2014
Computational Biology and Bioinformatics
The human syndrome Xeroderma Pigmentosum (XP) is a rare genetic disease characterized by high sensitivity to sunlight, and, in some cases, early aging and neurodegeneration. Defects on eight…
ISEF · 2014
Computational Biology and Bioinformatics
The purpose of this experiment was to determine the effects of triclosan on the muscle functioning of a Pomacea diffusa snail. Triclosan is an antibacterial chemical found in consumer produc…
ISEF · 2014
Computational Biology and Bioinformatics Third Award
With over 34 million people living with HIV today, a prophylactic vaccine is urgently needed.Due to a history of vaccine failure, a novel vaccine modality is necessary. Researchers studying…
ISEF · 2014
Computational Biology and Bioinformatics
Our project involves analyzing sets of genomic sequences and the underlying similarities and interconnected relations between them. Our project makes use of homology groups and the Smith-Wat…
ISEF · 2014
Computational Biology and Bioinformatics Fourth Award
Tumor-associated lymphatics play an important role in tumor growth and metastasis. In this in vitro study, gold nanoshell (AuNS) mediated photothermolysis of lymphatic endothelial cells (LEC…
ISEF · 2014
Computational Biology and Bioinformatics
Cellular processes like motility, morphogenesis, and differentiation are heavily governed by the physical properties of the cell. For example, cellular stiffness is a primary indicator of th…
ISEF · 2014
Computational Biology and Bioinformatics
Understanding phosphorylation of Zip1’s M region can elucidate required meiotic mechanisms. The study focused on understanding the phopsholitic importance of suspected critical serines: 512,…