38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2014
Computational Biology and Bioinformatics Third Award
The purpose of this study was to determine the potential changes in the expression of microRNAs -155, -146a, -29a, and -21 in macrophages cultured under diabetic conditions. MicroRNA (miRNA)…
ISEF · 2014
Computational Biology and Bioinformatics
Regenerative medicine is seen as the future for cardiovascular health. Adult human cardiomyocytes have very little proliferative capacity. However, neonatal mice have shown very high levels…
ISEF · 2014
Computational Biology and Bioinformatics
Macrophages are vital cells of the immune system with roles in protecting against infection. Macrophages internalize chemicals or pathogens through phagocytosis or pinocytosis. Macropinocyto…
ISEF · 2014
Computational Biology and Bioinformatics
Resveratrol is known as a powerful antioxidant present in many foods, especially in grapes and red wine. My study investigated the mutagenic effects of three increasing concentrations of Res…
ISEF · 2014
Computational Biology and Bioinformatics
Endothelial Cells form blood vessels, so knowing of how Macrophages and Endothelial Cells interact can be beneficial in finding therapies for diseases such as Cardiovascular disease, atheros…
ISEF · 2014
Computational Biology and Bioinformatics Third Award
The main objective of my project is to develop the simple, cost-effective, reusable electrochemical sensor (electronic tongue) that can simultaneously and accurately detect cadmium (Cd), mer…
ISEF · 2014
Computational Biology and Bioinformatics
NG2-glia are a class of glial cells in the brain that play a critical role in synaptic regulation and myelination through their structural support of axons and oligodendrocytes. In the insta…
ISEF · 2014
Computational Biology and Bioinformatics
Visualizing differentiation of cancer cells is a crucial method of measuring cancer progression. A novel fluorescent protein reporter construct was designed with the purpose of recombining t…
ISEF · 2014
Computational Biology and Bioinformatics
During the course of the past two years, the effects of antioxidants on cell viability and bacterial growth have been tested. The addition of anthocyanins to cancer cell cultures significant…
ISEF · 2014
Computational Biology and Bioinformatics
Coal is one of the world’s largest assets in terms of energy, in 2012 coal provided 41% of the entire worlds electricity. In order to provide so much energy large reserves of coal were burne…
ISEF · 2014
Computational Biology and Bioinformatics
Researchers and medical professionals are inundated with tremendous amounts of genomic ‘big data’. However, there is a lack of tools that are capable of offering insightful interpretations o…
ISEF · 2014
Computational Biology and Bioinformatics
It is envisaged that fluorescent quenching based on solution or extract deriving from plants could post as a new chemosensoring process for selective recognition of metal ions. In the fabric…
ISEF · 2014
Computational Biology and Bioinformatics
Actinoplanes teichomyceticus is a producer of antibiotic, teicoplanin, which acts against multi-resistant G+ pathogens. There are few industrial teicoplanin-overproducing strains with increa…
ISEF · 2014
Computational Biology and Bioinformatics
The health and well-being of populations in certain critical regions of the world are threatened today by the presence of counterfeit pharmaceuticals which are often authentic materials dilu…
ISEF · 2014
Computational Biology and Bioinformatics
Induced pluripotent stem cells (iPSCs) have the ability to circumvent the issues associated with obtaining specialized cells for in vitro models, and provide a new frontier in the field of i…
ISEF · 2014
Computational Biology and Bioinformatics
Hepatitis C Virus (HCV) has transformed from a silent disease to become a threat to the world, with approximately 170 million people infected globally. Although HCV genotype 4 (HCV-4) is the…
ISEF · 2014
Computational Biology and Bioinformatics
The role of the gene IKKß in the development of lymphocytes, macrophages and neutrophils is well known, but little is known about its role in the development of dendritic cells (DCs). In thi…
ISEF · 2014
Computational Biology and Bioinformatics
Among the universe of stem cells, adult mesenchymal cells have demonstrated a great potential to many disease treatment. Although these cells are disseminated in the human body, and neither…
ISEF · 2014
Computational Biology and Bioinformatics
Rap1 is key protein in regulating a cell signaling pathway that controls cell adhesion to its environment. Being able to manipulate and shutdown this pathway would yield immense benefits for…
ISEF · 2014
Computational Biology and Bioinformatics
As medication in Middle Eastern countries is delivered to consumers in their original factory box, fraud where expired medicine is commercialized has become a typical issue. A novel mechanis…
ISEF · 2014
Computational Biology and Bioinformatics
The purpose of this research was to create a new non-invasive test that could detect food based non-IgE mediated food allergies using saliva and antigens. A convenience sample of four indivi…
ISEF · 2014
Computational Biology and Bioinformatics Second Award
The human genome contains upwards of 20,000 genes that code for functional products, such as proteins. In addition to genes, the genome encodes regulatory elements that respond to specific s…
ISEF · 2014
Computational Biology and Bioinformatics Fourth Award
Mutations in the MeCP2 gene are the most common cause of Rett Syndrome (RTT), a severe form of autism diagnosed primarily in girls. The MeCP2 gene product, MeCP2, is a transcriptional regula…
ISEF · 2014
Computational Biology and Bioinformatics
Cell locomotion and cell aggregation are part of the large blank areas in our biological knowledge today. Many scientists focus on targeting cancer with different compounds. However, Gliobla…
ISEF · 2014
Computational Biology and Bioinformatics
In eukaryotes, the export of mRNA from the nucleus to the cytoplasm via the nuclear pore complex is an essential step in the gene expression pathway. Although the role of nucleoporins in nuc…
ISEF · 2014
Computational Biology and Bioinformatics Fourth Award
Nanotechnology has played a significant role in modern medical application. Nanocarriers are able to deliver the chemotherapeutic drugs and deliver them specifically to the targeted cells. A…
ISEF · 2014
Computational Biology and Bioinformatics
Liquid Organic Hydrogen Carriers (LOHCs) are one of the most promising concepts for a new alternative renewable energy source. LOHCs are chemical compounds in which large amounts of hydrogen…
ISEF · 2014
Computational Biology and Bioinformatics
Pulmonary Lymphangioleiomyomatosis (LAM) is a rare progressive, often-fatal lung disease associated with a mutation in either a TSC1 or TSC2 gene. LAM is manifested in three forms: slow-deve…
ISEF · 2014
Computational Biology and Bioinformatics
About a decade ago it was discovered by Italian scientists that the Briggs-Rauscher oscillating reaction is sensitive to antioxidants. These free-radical scavengers inhibit the reaction; the…
ISEF · 2014
Computational Biology and Bioinformatics
With the world population increasing by 60 million every year, the search for clean water becomes a growing concern especially in Less Economically Developed Countries (LEDCs). Waste of anim…