Browse real student projects, abstracts, and awards.
ISEF · 2014
Computational Biology and Bioinformatics
Rap1 is key protein in regulating a cell signaling pathway that controls cell adhesion to its environment. Being able to manipulate and shutdown this pathway would yield immense benefits for…
ISEF · 2014
Computational Biology and Bioinformatics
As medication in Middle Eastern countries is delivered to consumers in their original factory box, fraud where expired medicine is commercialized has become a typical issue. A novel mechanis…
ISEF · 2014
Computational Biology and Bioinformatics
The purpose of this research was to create a new non-invasive test that could detect food based non-IgE mediated food allergies using saliva and antigens. A convenience sample of four indivi…
ISEF · 2014
Computational Biology and Bioinformatics Second Award
The human genome contains upwards of 20,000 genes that code for functional products, such as proteins. In addition to genes, the genome encodes regulatory elements that respond to specific s…
ISEF · 2014
Computational Biology and Bioinformatics Fourth Award
Mutations in the MeCP2 gene are the most common cause of Rett Syndrome (RTT), a severe form of autism diagnosed primarily in girls. The MeCP2 gene product, MeCP2, is a transcriptional regula…
ISEF · 2014
Computational Biology and Bioinformatics
Cell locomotion and cell aggregation are part of the large blank areas in our biological knowledge today. Many scientists focus on targeting cancer with different compounds. However, Gliobla…
ISEF · 2014
Computational Biology and Bioinformatics
In eukaryotes, the export of mRNA from the nucleus to the cytoplasm via the nuclear pore complex is an essential step in the gene expression pathway. Although the role of nucleoporins in nuc…
ISEF · 2014
Computational Biology and Bioinformatics Fourth Award
Nanotechnology has played a significant role in modern medical application. Nanocarriers are able to deliver the chemotherapeutic drugs and deliver them specifically to the targeted cells. A…
ISEF · 2014
Computational Biology and Bioinformatics
Liquid Organic Hydrogen Carriers (LOHCs) are one of the most promising concepts for a new alternative renewable energy source. LOHCs are chemical compounds in which large amounts of hydrogen…
ISEF · 2014
Computational Biology and Bioinformatics
Pulmonary Lymphangioleiomyomatosis (LAM) is a rare progressive, often-fatal lung disease associated with a mutation in either a TSC1 or TSC2 gene. LAM is manifested in three forms: slow-deve…
ISEF · 2014
Computational Biology and Bioinformatics
About a decade ago it was discovered by Italian scientists that the Briggs-Rauscher oscillating reaction is sensitive to antioxidants. These free-radical scavengers inhibit the reaction; the…
ISEF · 2014
Computational Biology and Bioinformatics
With the world population increasing by 60 million every year, the search for clean water becomes a growing concern especially in Less Economically Developed Countries (LEDCs). Waste of anim…
ISEF · 2014
Computational Biology and Bioinformatics
Neuroblastoma is an aggressive pediatric cancer, with two thirds of all cases found in children ages five or younger. Current drugs cause adverse side effects which greatly affects the devel…
ISEF · 2014
Computational Biology and Bioinformatics
Chloramines have been used to disinfect potable water because they do not product carcinogenic DBP’s like traditional free chlorine. However, chloramines have been linked with lead leaching…
ISEF · 2014
Computational Biology and Bioinformatics Second Award
One in eight women will be diagnosed with a form of noninvasive Breast cancer during her lifetime. NEK2 is a highly-expressed gene in Breast cancer. The objective was to determine the role N…
ISEF · 2014
Computational Biology and Bioinformatics
The adult muscle has stem cells called satellite cells. Those cells are quiescent in a normal situation and they get activated after injury. The most important function of satellite cells is…
ISEF · 2014
Computational Biology and Bioinformatics
Cell culture is challenging due to the use of medium components such as fetal bovine serum and human serum, risk of transmission of microbial disease, allergies, and ethical issues. Thus, id…
ISEF · 2014
Computational Biology and Bioinformatics
This experiment analyzed the effects of solute concentration on the optical rotation of various chiral molecules by building a polarimeter to measure their angle of rotation and comparing th…
ISEF · 2014
Computational Biology and Bioinformatics
Eye-color genotypes are good predictors of eye-color phenotypes. The purpose of this project was to go the other direction and see if eye-color genotypes could be predicted based on eye-colo…
ISEF · 2014
Computational Biology and Bioinformatics
New evidences have revealed that the protozoan parasite Plasmodium falciparum uses a communication net based on the releasing extracellular vesicles from infected red blood cells. The conten…
ISEF · 2014
Computational Biology and Bioinformatics
Virus production is a limiting factor in fields that utilize viral platforms, including the fields of vaccinology, oncolytic virology, and gene therapy. Previous research has suggested that…
ISEF · 2014
Computational Biology and Bioinformatics
The purpose of this study was to screen several VHH nanobodies for effective intracellular binding to a-Synuclein (Syn), whose aggregation is associated with Parkinson’s disease. Previously,…
ISEF · 2014
Computational Biology and Bioinformatics Fourth Award
Damage to the heart muscle has long been considered irreparable and an indicator of future heart failure. When damaged, the heart forms a scar-like tissue that develops over regions of damag…
ISEF · 2014
Computational Biology and Bioinformatics
Bipolar disorder is a psychiatric disorder with phases of mania and depression. Past studies have implicated a relationship between bipolar disorder and NMDA receptor which is a glutamate re…
ISEF · 2014
Computational Biology and Bioinformatics
Cancer cells express surface proteins when they are formed, and among the proteins is MICA. MICA is recognized by human immune system such as NK cell, and NK cells secrete cytokines to remov…
ISEF · 2014
Computational Biology and Bioinformatics
The purpose of “Stay Home or Go Global - Local Versus Imported Fruit?” is to study what pesticides we may be eating and which fruits might be the worst ones. Pesticides can be fungicides or…
ISEF · 2014
Computational Biology and Bioinformatics Second Award
The fabrication of laser grade ceramics must be improved to achieve better reproducibility of high quality yields, requiring a control of the bulk stoichiometry beyond that of current analyt…
ISEF · 2014
Computational Biology and Bioinformatics
Malonyl-CoA:ACP Transacylase (MCAT) is a mitochondrial enzyme needed for the functionality of pyruvate dehydrogenase (PDH). PDH is known to play a critical role in a tumor suppressor network…
ISEF · 2014
Computational Biology and Bioinformatics First Award
Monosodium Glutamate (MSG) is one of the most commonly used spices for taste enhancement. Research has shown that people are sensitive to MSG and that all organs of the body contain glutamat…
ISEF · 2014
Computational Biology and Bioinformatics Second Award
Glioblastoma Multiforme is the most frequent and devastating malignant brain tumor among adults with an average life expectancy of one year after diagnosis. This is partly due to its multi-d…