38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2017
Computational Biology and Bioinformatics
Huntington's disease (HD) is a fatal genetic neurogenerative disorder caused by expansion of CAG trinucleotide repeats in the huntingtin (HTT) gene greater than 35 repeats. The expanded CAG…
ISEF · 2017
Computational Biology and Bioinformatics
Artificial neural networks, models of which were experimentally calibrated by the author, train homeostatic variable sets to examine the relationship between variations in incubation conditi…
ISEF · 2017
Computational Biology and Bioinformatics Fourth Award
People with Type 1 Diabetes must compute an insulin dose for every meal. Dosing errors can cause both acute and chronic complications. The current dosing method (i.e., "carb counting") consi…
ISEF · 2017
Computational Biology and Bioinformatics
Alzheimer’s disease and Parkinson’s disease are chronic, debilitating neurodegenerative disorders, and the ability to accurately diagnose and monitor these diseases is critical for treatment…
ISEF · 2016
Computational Biology and Bioinformatics
What I hope to achieve in this experiment is to determine the percentage of students who have anxiety disorders, if females have it more commonly than males, or vise versa, and what age grou…
ISEF · 2016
Computational Biology and Bioinformatics
The researcher believes that if humans are exposed to human attractant pheromones, they will rate people as more attractive and believe each person is more successful. The experiment include…
ISEF · 2015
Computational Biology and Bioinformatics
Speech is produced by a set of neurological and motor processes, known as speech motor programming. When regions of the brain controlling speech are damaged, speakers are not able to properl…
ISEF · 2015
Computational Biology and Bioinformatics
Often times, there are instances where making certain decisions are harder than others. One may think that a person who has trouble deciding in one area should also be indecisive across a br…
ISEF · 2015
Computational Biology and Bioinformatics
The study investigated the thermogenic properties of green coffee bean extract on a nonparametric group, as well as placebo expectancy in regards to weight loss. Subjects were measure in fou…
ISEF · 2015
Computational Biology and Bioinformatics
The purpose of the project is to test how localized vibrations affect the physiological signals of children. If vibrations are proven successful in calming children down, then vibration ther…
ISEF · 2014
Computational Biology and Bioinformatics
The purpose of this experiment was to characterize a newly discovered ultrastable silver nanoparticle. Silver is known to be susceptible to oxidation while metals such as gold and platinum a…
ISEF · 2014
Computational Biology and Bioinformatics Fourth Award
Upon encountering antigens in the germinal centers of peripheral lymphoid organs such as the spleen or lymph nodes, mature B-lymphocytes undergo class switch recombination (CSR). CSR alters…
ISEF · 2014
Computational Biology and Bioinformatics
Glaucoma is a neurodegenerative disease that causes ganglion cell death in the retina, leading to vision loss. To study the effects of glaucoma, the DBA/2J mouse has proven to be a precise m…
ISEF · 2014
Computational Biology and Bioinformatics Second Award
My research develops a tool to enable the first ever genome-wide analysis of genetic variants, specifically single nucleotide polymorphisms (SNPs), in transcription factor binding sites. The…
ISEF · 2014
Computational Biology and Bioinformatics
Alzheimer’s disease (AD) is a neurodegenerative disorder resulting from the buildup of neuritic plaques and neurofibrillary tangles. Those with AD exhibit worsening memory and language funct…
ISEF · 2014
Computational Biology and Bioinformatics
In this study, I conducted laboratory tests that produced induced pluripotent stem cells (iPS) that could be used as an alternative to the use of embryonic stem cells. Using human buccal che…
ISEF · 2014
Computational Biology and Bioinformatics
Lymphopenia, a condition in which the number of lymphocytes falls below normal levels, makes patients more susceptible to infection and disease, and can be caused by genetic predisposition o…
ISEF · 2014
Computational Biology and Bioinformatics First Award
As the leading cause of cancer-related deaths in women worldwide, breast cancer metastasis remains refractory to current therapy. Residing in the Polycomb protein group and altering the chro…
ISEF · 2014
Computational Biology and Bioinformatics
Analyzing how drugs affect the cell cycle requires cell cycle analysis. An approach using flow cytometry is limiting as the only parameter that can be collected is intensity. In order to obt…
ISEF · 2014
Computational Biology and Bioinformatics
New transition metal complexes of Co(II), Ni(II), Cu(II) and Zn(II) with the Schiff bases derived by condensation of 3-formyl-2-hydroxy quinoline with Guanine(GUOH) and 3-formyl-2-mercapto q…
ISEF · 2014
Computational Biology and Bioinformatics Fourth Award
Fruits and vegetables provide us nutrition including vitamins and minerals to stay healthy – both mentally and physically. In pursuit of a pest-free produce, farmers use pesticides, far abov…
ISEF · 2014
Computational Biology and Bioinformatics
Chemotherapy is currently the number one remedy for cancer. The side effects are significant and lead to various problems such as hair loss. Recently research has shown that compounds such a…
ISEF · 2014
Computational Biology and Bioinformatics
Parkinson’s disease (PD) is caused by the unknown death of dopamine-generating cells in the substantia nigra. The pathology of PD is determined by neurodegeneration of dopaminergic neuron an…
ISEF · 2014
Computational Biology and Bioinformatics
This study aims to characterize the role of p53, a tumor suppressor protein, in tumor-initiating cells. An emerging theory in cancer research is that tumor progenitor cells can give rise to…
ISEF · 2014
Computational Biology and Bioinformatics
Damage to mitochondrial DNA is correlated with a wide array of diseases, such as diabetes, obesity, heart disease, and aging. MtDNA can be depleted experimentally by treating cells with ethi…
ISEF · 2014
Computational Biology and Bioinformatics Third Award
Human Immunodeficiency Virus (HIV) causes immunosuppression resulting in acquired immunodeficiency syndrome (AIDS). A closely related virus, Simian Immunodeficiency Virus (SIV), is commonly…
ISEF · 2014
Computational Biology and Bioinformatics First Award
Induced pluripotent stem cells (iPSCs) could revolutionize patient-specific regenerative medicine, but their premature aging symptoms, currently misunderstood, limit their clinical applicabi…
ISEF · 2014
Computational Biology and Bioinformatics
To separate and identify metallic ions, precipitation and filtration should be repeated. Furthermore, many kinds of reagents should be used and operations are complicated. A new method for s…
ISEF · 2014
Computational Biology and Bioinformatics
A byproduct of many cellular metabolic reactions is reactive oxygen species (ROS). An increase in ROS levels or a decrease in the cellular antioxidant capacity causes oxidative stress and is…
ISEF · 2014
Computational Biology and Bioinformatics Third Award
The zebrafish (Danio rerio) lateral line consists of a system of sensory organs that are optimal for in vivo studies of hair cell death and protection. Zebrafish hair cells are both structur…