38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2018
Computational Biology and Bioinformatics
Empirical evidence demonstrates that an organism’s phenotypes are often based on multiple interdependent genes, rather than a single gene. When the expression of a phenotype is predicated on…
ISEF · 2018
Computational Biology and Bioinformatics
Detecting rare cell types would allow very early disease diagnosis (e.g., cancer, infection), identification of new cell types, and deepen our understanding of cell differentiation. We devel…
ISEF · 2018
Computational Biology and Bioinformatics Fourth Award
Kinesins are motor proteins that move unidirectionally along microtubules as they hydrolyze ATP. Although the general features of the kinesin walking mechanism are becoming increasingly clea…
ISEF · 2018
Computational Biology and Bioinformatics
Epilepsy is a very common and devastating neurological disorder that affects 65 million people globally. Electroencephalography (EEG) recording is an essential tool in evaluating seizure act…
ISEF · 2018
Computational Biology and Bioinformatics
P53 is an important tumor suppressor protein, that when mutated will lead to much higher cancer rate. This project constructed a phylogenetic tree using the mRNA sequences for p53 gene in 20…
ISEF · 2018
Computational Biology and Bioinformatics
Sensory hearing hair-cells are vulnerable to multiple damaging agents. In mammals, which lack regeneration, hair-cell loss leads to permanent hearing impairment. In contrast, non-mammalian v…
ISEF · 2018
Computational Biology and Bioinformatics
Ischemic strokes, caused by limited blood flow to the brain due to clotted arteries, account for 88% of all strokes, and are one of the leading causes of death worldwide. Although a cure has…
AJAS · 2018
Computational Biology and Bioinformatics (inferred)
Epilepsy is a chronic brain disorder affecting 1% of the population worldwide. Its primary symptoms, seizures, occur without warning and can often be dangerous. Epilepsy is diagnosed with th…
ISEF · 2018
Computational Biology and Bioinformatics
Parkinson’s disease (PD) is identified and associated with symptoms such as changes in gait stability, slowness of movement, essential tremor, and changes in cognitive function. Symptoms and…
ISEF · 2018
Computational Biology and Bioinformatics
The purpose of this in-silico experiment was to explore a way to model the transition of bacterial populations (persister and normal). The hypothesis theorizes that by studying the role of r…
ISEF · 2018
Computational Biology and Bioinformatics
States and the CDC monitor accidental and intentional violent deaths to answer questions that are critical for the development of effective violence prevention strategies. The National Viole…
AJAS · 2018
Computational Biology and Bioinformatics (inferred)
Mouse models serve as a readily available base for experimentation in neurodegenerative drug development. However, less than 10% of drugs that have shown success in mouse-based preclinical t…
ISEF · 2017
Computational Biology and Bioinformatics
It was previously reported, that temperature may significantly influence neural dynamics on different levels of brain modeling. Therefore, in computational neuroscience, we would like to con…
ISEF · 2017
Computational Biology and Bioinformatics
Unlike homogeneous cellular bodies, cancer is best understood as a diverse community of heterogeneous cells that interacts through complex ecological interactions. Intratumor interactions, s…
ISEF · 2017
Computational Biology and Bioinformatics
Safe, effective, and reliable gene therapy has been heralded as the future of medicine in the 21st century. Technologies for editing and regulating genes based on the CRISPR/Cas9 system have…
ISEF · 2017
Computational Biology and Bioinformatics
Microarray technologies are used to understand the driving forces in genomics and proteomics through high-throughput measurements of interactions among DNA, RNA, peptides, and proteins. Univ…
ISEF · 2017
Computational Biology and Bioinformatics
Alzheimer’s affects 44 million people worldwide but has no preventive cures. This study created a novel methodology for Alzheimer’s (AD) and Mild Cognitive Impairment’s (MCI) early detection…
ISEF · 2017
Computational Biology and Bioinformatics
Cancer is among the most debilitating diseases in the world with its pervasiveness originating from its complex genetic makeup. Although cancer research is at the forefront of medical concer…
ISEF · 2017
Computational Biology and Bioinformatics
Autism Spectrum Disorder (ASD) is a common neurodevelopmental disorder characterized by behavioral irregularities. Causal variation has been implicated in only 30-40% of ASD diagnoses; it is…
ISEF · 2017
Computational Biology and Bioinformatics Fourth Award
Eye cancer has affected over 500,000 people worldwide in the past decade. Approximately 10% of people with eye cancer will die because it is not diagnosed early enough, causing it to metasta…
ISEF · 2017
Computational Biology and Bioinformatics
The formation of a hairpin core structure by the human immunodeficiency virus type 1 (HIV-1) transmembrane glycoprotein gp41 is the critical event that triggers viral fusion to the host cell…
ISEF · 2017
Computational Biology and Bioinformatics
Melanoma is one of the deadliest forms of skin cancer, causing 80% of skin cancer mortalities. However, it is fully curable if diagnosed early. Diagnosis is conducted by visually examining l…
ISEF · 2017
Computational Biology and Bioinformatics Third Award
Cancer is among the leading causes of death around the world. Immunotherapies have the potential to improve cancer survival by utilizing the immune system for treatment and reducing radiatio…
ISEF · 2017
Computational Biology and Bioinformatics
This project was fabricated on the foundation of Computation Biology with the real time predictive modelling for mitigating contagious diseases with a mathematical approach. The aim of this…
ISEF · 2017
Computational Biology and Bioinformatics
Obsessive-compulsive disorder (OCD) is the fourth most common psychiatric disorder. Mitochondria are organelles that exert key functions in the nervous system. This research project investig…
ISEF · 2017
Computational Biology and Bioinformatics Second Award
Neurological manifestations of recent viral outbreaks such as congenital microcephaly and Guillain-Barré Syndrome associated with Zika (ZIKV) infection are a global concern. An urgent need e…
ISEF · 2017
Computational Biology and Bioinformatics
Alternative splicing is an inherent gene regulatory mechanism, allowing for a single gene to code for a multitude of proteins. Intron retention (IR) is a class of alternative splicing variat…
ISEF · 2017
Computational Biology and Bioinformatics
Zika Virus (ZIKV) poses a considerable threat to human life, with over 100,000 cases confirmed. Since no treatments or drugs are available, a novel approach was created to expedite the ident…
ISEF · 2017
Computational Biology and Bioinformatics
The high incidences of Dengue, Chikungunya, Zika and Yellow Fever epidemics have become a worrying factor for public health authorities. Aedes aegypti is the main transmission agent for thos…
ISEF · 2017
Computational Biology and Bioinformatics Fourth Award
It is hypothesized that variable release methods for genetically modified Aedes aegypti will control wild mosquito populations using the least number of modified mosquitoes. Aedes aegypti mo…