Browse real student projects, abstracts, and awards.
ISEF · 2017
Computational Biology and Bioinformatics
Cancer is among the most debilitating diseases in the world with its pervasiveness originating from its complex genetic makeup. Although cancer research is at the forefront of medical concer…
ISEF · 2017
Computational Biology and Bioinformatics
Autism Spectrum Disorder (ASD) is a common neurodevelopmental disorder characterized by behavioral irregularities. Causal variation has been implicated in only 30-40% of ASD diagnoses; it is…
ISEF · 2017
Computational Biology and Bioinformatics Fourth Award
Eye cancer has affected over 500,000 people worldwide in the past decade. Approximately 10% of people with eye cancer will die because it is not diagnosed early enough, causing it to metasta…
ISEF · 2017
Computational Biology and Bioinformatics
The formation of a hairpin core structure by the human immunodeficiency virus type 1 (HIV-1) transmembrane glycoprotein gp41 is the critical event that triggers viral fusion to the host cell…
ISEF · 2017
Computational Biology and Bioinformatics
Melanoma is one of the deadliest forms of skin cancer, causing 80% of skin cancer mortalities. However, it is fully curable if diagnosed early. Diagnosis is conducted by visually examining l…
ISEF · 2017
Computational Biology and Bioinformatics Third Award
Cancer is among the leading causes of death around the world. Immunotherapies have the potential to improve cancer survival by utilizing the immune system for treatment and reducing radiatio…
ISEF · 2017
Computational Biology and Bioinformatics
This project was fabricated on the foundation of Computation Biology with the real time predictive modelling for mitigating contagious diseases with a mathematical approach. The aim of this…
ISEF · 2017
Computational Biology and Bioinformatics
Obsessive-compulsive disorder (OCD) is the fourth most common psychiatric disorder. Mitochondria are organelles that exert key functions in the nervous system. This research project investig…
ISEF · 2017
Computational Biology and Bioinformatics Second Award
Neurological manifestations of recent viral outbreaks such as congenital microcephaly and Guillain-Barré Syndrome associated with Zika (ZIKV) infection are a global concern. An urgent need e…
ISEF · 2017
Computational Biology and Bioinformatics
Alternative splicing is an inherent gene regulatory mechanism, allowing for a single gene to code for a multitude of proteins. Intron retention (IR) is a class of alternative splicing variat…
ISEF · 2017
Computational Biology and Bioinformatics
Zika Virus (ZIKV) poses a considerable threat to human life, with over 100,000 cases confirmed. Since no treatments or drugs are available, a novel approach was created to expedite the ident…
ISEF · 2017
Computational Biology and Bioinformatics
The high incidences of Dengue, Chikungunya, Zika and Yellow Fever epidemics have become a worrying factor for public health authorities. Aedes aegypti is the main transmission agent for thos…
ISEF · 2017
Computational Biology and Bioinformatics Fourth Award
It is hypothesized that variable release methods for genetically modified Aedes aegypti will control wild mosquito populations using the least number of modified mosquitoes. Aedes aegypti mo…
ISEF · 2017
Computational Biology and Bioinformatics
Substance use disorder is characterized by the chronic use of addictive substances, to the point where substance use is beyond the user’s control. Both genetic and environmental factors dete…
ISEF · 2017
Computational Biology and Bioinformatics Second Award
The emergence of high-throughput histopathological images over the past decade provides new opportunities for computational techniques to study cancerous tumors. Current analysis of tumor pr…
ISEF · 2017
Computational Biology and Bioinformatics Fourth Award
Pancreatic cancer (PC) is currently one of the deadliest cancers, with a 5-year survival rate of just 7%. Detecting PC while it is localized increases the survival rate to 30%, however to da…
ISEF · 2017
Computational Biology and Bioinformatics
The purpose of the research conducted was to optimize treatments for the world’s deadliest disease, Ischemic Heart Disease, by using the most novel tools available: CRISPR and Machine Learni…
ISEF · 2017
Computational Biology and Bioinformatics
Life of all organisms is largely regulated by protein-protein interactions. In particular, immune system reactions are provided by those interactions. When our immune system fails, scientist…
ISEF · 2017
Computational Biology and Bioinformatics
With over 19,000 genes in the human genome, an effective method to link genes to the progression of cancer is needed. The identification of even one novel significant gene in the progression…
ISEF · 2017
Computational Biology and Bioinformatics
Studying the 3D topology of the genome, in which DNA interacts to form loops, has become a promising field for building a better understanding of tumor biology. Although identifying 3D genom…
ISEF · 2017
Computational Biology and Bioinformatics
Altruism is the tendency of individuals to behave in ways that benefit the whole at the expense of the individual. Due to the complexity of interactions between living organisms, it is chall…
ISEF · 2017
Computational Biology and Bioinformatics Third Award
Type 1 diabetes mellitus (T1D) affects three million individuals in the United States alone, resulting in approximately $15 billion in healthcare costs annually. T1D results from the autoimm…
ISEF · 2017
Computational Biology and Bioinformatics
Metastasis causes 100% of deaths from breast cancer, the most common cancer in women worldwide. Fusion genes, a combination of two genes due to genetic structural variation, are potential dr…
ISEF · 2017
Computational Biology and Bioinformatics
This research presents a computational pipeline for single nucleotide polymorphism (SNP) analysis. Due to the scientific potential of the complex and multifaceted information provided by SNP…
ISEF · 2017
Computational Biology and Bioinformatics
Type 2 diabetes mellitus (T2DM) is considered one of the top comorbidities in the Middle East. WHO reported in 2010 that the average prevalence of diabetes in this region is 9.3%. Variations…
ISEF · 2017
Computational Biology and Bioinformatics
More than 98% of the human genome is defined as non-coding DNA. Many of these noncoding elements are simply remnants of ancient genetic material, but studies indicate that 5% of the genome i…
ISEF · 2017
Computational Biology and Bioinformatics
Twenty-percent of women in the United States are affected by breast cancer. Estrogen-receptor negative cancer treatments for postmenopausal women often worsen symptoms of osteoporosis, resul…
ISEF · 2017
Computational Biology and Bioinformatics
The purpose of this experiment was to find the correlation between the complexity of leaf vein structure and the speed at which leaves dry, as determined by the rate of embolism formation. M…
ISEF · 2017
Computational Biology and Bioinformatics
In the past two decades, zebrafish stripes have been immensely studied and their formation continues to lend itself to a better understanding of pigmentation patterns as a whole (Smith, 2015…
ISEF · 2017
Computational Biology and Bioinformatics
The kth nearest neighbor algorithm (kNN) is a non-parametric method used for classification, in which a query point is compared to a data set of points with predetermined classes. The neares…