Browse real student projects, abstracts, and awards.
ISEF · 2024
Computational Biology and Bioinformatics
Transdermal drug delivery (TDD) has emerged as a reliable alternative to invasive drug administration techniques. However, current methods used to test the process of TDD are inefficient and…
ISEF · 2024
Computational Biology and Bioinformatics Fourth Award
The aim of this research is to detect tumor tissue during brain surgery using data preprocessing and machine learning. Brain tumors are the leading cause of cancer-related death in children…
ISEF · 2024
Computational Biology and Bioinformatics Third Award
Parkinson's Disease (PD) is a neurodegenerative disease that causes gradual impairment of an individual through mutations in the SNCA (Synuclein Alpha) gene. Currently, there exist no widely…
ISEF · 2024
Computational Biology and Bioinformatics Fourth Award
In the human brain, high amounts of metabolic energy are required to maintain neural activity. A large fraction of this energy is expended in the generation and firing of action potentials,…
ISEF · 2024
Computational Biology and Bioinformatics
Colorectal cancer (CRC) represents a major health challenge with significant mortality rates. Due to the difficulties in early intervention, many patients fail to receive optimal therapeutic…
ISEF · 2024
Computational Biology and Bioinformatics
Native Hawaiian Pacific Islanders (NHPI) suffer disproportionately from cardiometabolic health conditions compared to other major ethnic groups. This study aimed to address critical gaps in…
ISEF · 2024
Computational Biology and Bioinformatics
Affecting 60-70% of the 55 million dementia patients in the world, Alzheimer's Disease (AD) has established itself as one of the most profound neurodegenerative diseases in today's society.…
ISEF · 2024
Computational Biology and Bioinformatics First Award
Alzheimer's Disease (AD) has neither satisfactory nor equitably accessible treatments. Current research emphasizes inflammation, notably age-related elevation of microglial TNF-a, in driving…
ISEF · 2024
Computational Biology and Bioinformatics
Dysregulated metabolism is a hallmark of cancer progression yet exactly how cancer cells vary their metabolic program during tumorigenesis remains unknown. Moreover, metabolism is highly dyn…
ISEF · 2024
Computational Biology and Bioinformatics Third Award
Cellular reprogramming holds immense promise for novel therapeutics in fields like disease reversion and cellular regeneration. This field aims to control or perturb gene expression to induc…
ISEF · 2024
Computational Biology and Bioinformatics
B-cell acute lymphoblastic leukemia (B-ALL), the most common pediatric cancer, is characterized by the proliferation of immature, leukemic B-lymphocytes in the bone marrow. CAR-T cell therap…
ISEF · 2024
Computational Biology and Bioinformatics
P-glycoprotein (P-gp) is found in various tissues throughout the body, acting as an efflux pump that actively transports substances out of cells. As a result, P-gp plays an important role in…
ISEF · 2024
Computational Biology and Bioinformatics
With over 18 million new cancer diagnoses and nearly 10 million associated deaths per year, cancer remains a significant global health challenge. Pancreatic cancer is one of the deadliest fo…
ISEF · 2024
Computational Biology and Bioinformatics
This study aims to develop novel mathematical approaches for cancer treatment, specifically targeted gene therapy for cancer stem cells (CSCs) within tumors. CSCs, or ancestral cells, are ta…
ISEF · 2024
Computational Biology and Bioinformatics
Stem cells play a central role in the development of organisms; hence, studying them is of great importance. RE:IN modeling of systems involving them allows us to investigate their behaviors…
ISEF · 2024
Computational Biology and Bioinformatics
This study presents a computer simulation of a contact virus being spread by carriers in rectangular rooms with different width-to-length shapes. The simulated scenario is one where a predet…
ISEF · 2024
Computational Biology and Bioinformatics
Leigh Syndrome is a disorder that typically appears during childhood or before birth and it is caused by mutations in the mitochondrial protein SURF1. Although more than 80 mutations have be…
ISEF · 2024
Computational Biology and Bioinformatics
Alzheimer's Disease (AD) is a leading cause of death, affecting over 55 million worldwide. Despite its prevalence, there is no effective treatment or cure for AD. The acetylcholinesterase (A…
ISEF · 2024
Computational Biology and Bioinformatics
Glioblastoma multiforme is one of the deadliest forms of brain tumors. Many genes are associated with its formation, progression, and survival, but no consensus has been reached on which som…
ISEF · 2024
Computational Biology and Bioinformatics
HIV infection remains a global public health challenge. While current drug treatments effectively suppress HIV viral loads below the detection level, complete eradication of the virus remain…
ISEF · 2024
Computational Biology and Bioinformatics Fourth Award
Breast cancer affects 2.3 million women annually with the five-year survival rate for Triple-negative-breast-cancer (TNBC) being 12%. Current immunotherapy treatments are effective only in 2…
ISEF · 2024
Computational Biology and Bioinformatics
Background: Predicting origins of premature ventricular complexes (PVCs) based on a 12-lead electrocardiogram (EKG) is a laborious process. Artificial intelligence can automate the process m…
ISEF · 2024
Computational Biology and Bioinformatics
My research provides the theoretical storage of data in DNA, expressed using the four natural “A,” “C,” “G,” and “T” DNA nucleobases. The DNA-stored information may be actual biological geno…
ISEF · 2024
Computational Biology and Bioinformatics
This study investigates the relationship between the sequential organization of the brain, measured by functional magnetic resonance imaging (fMRI) scans, and both rest and task-based differ…
ISEF · 2024
Computational Biology and Bioinformatics Fourth Award
B-cell acute lymphoblastic leukemia (B-ALL) and acute myeloid leukemia (AML) are the 2 most common leukemias. The American Cancer Society estimates that there will be 59,610 leukemia cases a…
ISEF · 2024
Computational Biology and Bioinformatics Third Award
The rising prevalence of neurodegenerative dementia highlights the need for improved diagnostic accuracy. Many proposed clinical decision support systems (CDSS) require multiple disparate da…
ISEF · 2024
Computational Biology and Bioinformatics Fourth Award
Globally, numerous living organisms suffer from viral infections. Genome annotation is the process of mapping coding-sequences (CDS) of a genome. CDS are the portions of the genome that are…