Browse real student projects, abstracts, and awards.
ISEF · 2019
Computational Biology and Bioinformatics
Up to $18.7 billion is spent on the treatment of chronic wounds per year, which afflict over 6.5 million people per year. To combat this issue, we set out with the goal of analyzing and refi…
ISEF · 2019
Computational Biology and Bioinformatics
Research and advances in medicine have dramatically increased human longevity, with an ensuing increase in the prevalence of geriatric conditions including Alzheimer’s disease (AD), Lewy bod…
ISEF · 2019
Computational Biology and Bioinformatics
Though early cancer detection is vital to patient survival, most lung cancers are diagnosed late due to the lack of a routine screening test. While blood miRNAs hold potential for this purpo…
ISEF · 2019
Computational Biology and Bioinformatics
DNA sequencing of patient’s tumors allows computational methods to reveal unprecedented insights on their genomes. Analysis of mutations in tumor genomes allows inference of the underlying m…
ISEF · 2019
Computational Biology and Bioinformatics
The goal of this research project is to demonstrate how evolutionary path dependencies and population-level epistasis affect the adaptive plasticity of populations of artificial organisms. I…
ISEF · 2019
Computational Biology and Bioinformatics
The purpose of this project was to develop an algorithm capable of predicting protein structure. The first step was to research how other protein modeling software work like homology modelin…
ISEF · 2019
Computational Biology and Bioinformatics
Craniosynostosis, a congenital disease that affects 1 in 2000-2500 people, shares genetic mutations implicated in cancer progression, yet has not been studied as a potential predictive marke…
ISEF · 2019
Computational Biology and Bioinformatics
Annually, the environmental bacteria cause food-borne illnesses that affect over 50 million persons worldwide. Over half the pharmaceuticals utilize bacterial products. Less than 1% of the e…
ISEF · 2019
Computational Biology and Bioinformatics
Genetic disorders are very common in the general population. These disorders are caused by abnormalities in one’s genome (DNA), which in turn encodes the proteins that are expressed in one’s…
ISEF · 2019
Computational Biology and Bioinformatics
Everyday, 115 Americans die from opioid overdose. These opioids, such as morphine, are often used as pain-management therapeutics. However, morphine and other synthetic drugs induce adverse…
ISEF · 2019
Computational Biology and Bioinformatics
Alzheimer’s disease (AD) diagnosis is a challenge, with misdiagnosis rates at 20-30%. Proteomics has become a field of interest in the search for biomarkers for the early diagnosis of AD. Ho…
ISEF · 2019
Computational Biology and Bioinformatics
The mathematical analysis of human growth, from the zygote to the adult, is key to determining long and short term health and longevity. Many studies prior have sought to develop a systemati…
ISEF · 2019
Computational Biology and Bioinformatics Fourth Award
Secondary cancers, which develop as a result of initial radiation or chemotherapy treatments, are a major cause of morbidity and mortality in cancer survivors. Early prediction of the develo…
ISEF · 2019
Computational Biology and Bioinformatics
Understanding gene function is important for many reasons; in particular, one could examine the gene of a pathogen to find a weakness, or discover a gene in a human related to cancer. Annota…
ISEF · 2019
Computational Biology and Bioinformatics Fourth Award
The goal of this project was to create a comprehensive test, automated and not requiring laboratory blood analysis, for the prediction of diabetic retinopathy and cardiovascular risk, utiliz…
ISEF · 2019
Computational Biology and Bioinformatics
Lesions, or abnormalities in tissue, are common and can be very severe. Before they become lethal, it is imperative that they are properly scanned and detected, so that proper measures can b…
ISEF · 2019
Computational Biology and Bioinformatics
The Hardy-Weinberg Principle states that allele frequencies will not significantly change in 5 generations if there is an extremely large population size along with other factors. I compared…
ISEF · 2019
Computational Biology and Bioinformatics
Lineage tracing provides fundamental insights into the developmental trajectories of individual cells of complex organisms. Genetic labeling approaches, such as naturally-occurring mitochond…
ISEF · 2019
Computational Biology and Bioinformatics
The genetic disorder preeclampsia is characterized by severe hypertension and proteinuria during pregnancy. Our project investigated the role of lncRNA (long non-coding RNA) in the genetic p…
ISEF · 2019
Computational Biology and Bioinformatics
The p53 protein, known for its role in preventing cancer, can also become the cause of cancer when mutated. Finding a way to understand the protein and develop a way to reactivate it has bee…
ISEF · 2019
Computational Biology and Bioinformatics
Lung cancer is the leading cause of cancer-related deaths in men and women. In addition, many patients with progressive lung cancer develop latent radiation-induced respiratory damage. The p…