Computational Biology and Bioinformatics
More than 98% of the human genome is defined as non-coding DNA. Many of these noncoding elements are simply remnants of ancient genetic material, but studies indicate that 5% of the genome i…
Computational Biology and Bioinformatics
Twenty-percent of women in the United States are affected by breast cancer. Estrogen-receptor negative cancer treatments for postmenopausal women often worsen symptoms of osteoporosis, resul…
Computational Biology and Bioinformatics
The purpose of this experiment was to find the correlation between the complexity of leaf vein structure and the speed at which leaves dry, as determined by the rate of embolism formation. M…
Computational Biology and Bioinformatics
In the past two decades, zebrafish stripes have been immensely studied and their formation continues to lend itself to a better understanding of pigmentation patterns as a whole (Smith, 2015…
Computational Biology and Bioinformatics
The kth nearest neighbor algorithm (kNN) is a non-parametric method used for classification, in which a query point is compared to a data set of points with predetermined classes. The neares…
Computational Biology and Bioinformatics
Studying the effects of seizures in the brain is necessary to better understand and treat epilepsy. With the use of an electroencephalogram (EEG), researchers and health professionals can re…
Computational Biology and Bioinformatics
Second Award
Non-Small Cell Lung Cancer (NSCLC) is the most prominent form of Lung Cancer and kills at least 800,000 people each year. Early diagnosis of NSCLC yields higher survival rates among patients…
Computational Biology and Bioinformatics
Amyloids comprise of the amino acids that are the primary cause of Alzheimer's; an antibody that binds with high affinity to the amyloid has great potential of being an improved drug candida…
Computational Biology and Bioinformatics
It has been postulated that anxiety and personality type A are the source of a large number of diseases, both psychic and organic. The conductance of the skin, known as the galvanic response…
Computational Biology and Bioinformatics
If climate change persists, ocean warming and acidification will have catastrophic effects on coral reefs and marine biodiversity in the next 100 years. However, marine and coral biodiversit…
Computational Biology and Bioinformatics
This study had two goals: to identify frequencies within the gamma band, 30 to 100 Hz, that contribute the most electrical power during seizure periods, and to explore pre-seizure patterns a…
Computational Biology and Bioinformatics
Third Award
Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) are segments of proteins that lack a defined tertiary structure, giving them the ability to interconvert…
Computational Biology and Bioinformatics
To overcome ethical and technical concerns, humanized mouse models are often used to study the human immune system. Specifically, immunodeficient mice are engrafted with human fetal tissue a…
Computational Biology and Bioinformatics
The purpose of this study was to determine whether the California skipjack tuna fishery is sustainable or not. This particular study holds great importance in that no California fisheries ha…
Computational Biology and Bioinformatics
Third Award
Epilepsy is a chronic brain disorder affecting 1% of the population worldwide. Its primary symptoms, seizures, occur without warning and can often be dangerous. Epilepsy is diagnosed with th…
Computational Biology and Bioinformatics
"Controlling the sugar concentration in our daily drinks has become essential especially for diabetes. It’s also an important thing to farmers in order to know exactly how much sugar their f…
Computational Biology and Bioinformatics
Fourth Award
The goal of this research was to improve cancer diagnostics, specifically copy number detection methods. Accurately determining the abundance of oncogenes and tumor suppressors is necessary…
Computational Biology and Bioinformatics
Huntington's disease (HD) is a fatal genetic neurogenerative disorder caused by expansion of CAG trinucleotide repeats in the huntingtin (HTT) gene greater than 35 repeats. The expanded CAG…
Computational Biology and Bioinformatics
Artificial neural networks, models of which were experimentally calibrated by the author, train homeostatic variable sets to examine the relationship between variations in incubation conditi…
Computational Biology and Bioinformatics
Fourth Award
People with Type 1 Diabetes must compute an insulin dose for every meal. Dosing errors can cause both acute and chronic complications. The current dosing method (i.e., "carb counting") consi…
Computational Biology and Bioinformatics
Alzheimer’s disease and Parkinson’s disease are chronic, debilitating neurodegenerative disorders, and the ability to accurately diagnose and monitor these diseases is critical for treatment…