Computational Biology and Bioinformatics
Researchers and medical professionals are inundated with tremendous amounts of genomic ‘big data’. However, there is a lack of tools that are capable of offering insightful interpretations o…
Computational Biology and Bioinformatics
It is envisaged that fluorescent quenching based on solution or extract deriving from plants could post as a new chemosensoring process for selective recognition of metal ions. In the fabric…
Computational Biology and Bioinformatics
Actinoplanes teichomyceticus is a producer of antibiotic, teicoplanin, which acts against multi-resistant G+ pathogens. There are few industrial teicoplanin-overproducing strains with increa…
Computational Biology and Bioinformatics
The health and well-being of populations in certain critical regions of the world are threatened today by the presence of counterfeit pharmaceuticals which are often authentic materials dilu…
Computational Biology and Bioinformatics
Induced pluripotent stem cells (iPSCs) have the ability to circumvent the issues associated with obtaining specialized cells for in vitro models, and provide a new frontier in the field of i…
Computational Biology and Bioinformatics
Hepatitis C Virus (HCV) has transformed from a silent disease to become a threat to the world, with approximately 170 million people infected globally. Although HCV genotype 4 (HCV-4) is the…
Computational Biology and Bioinformatics
The role of the gene IKKß in the development of lymphocytes, macrophages and neutrophils is well known, but little is known about its role in the development of dendritic cells (DCs). In thi…
Computational Biology and Bioinformatics
Among the universe of stem cells, adult mesenchymal cells have demonstrated a great potential to many disease treatment. Although these cells are disseminated in the human body, and neither…
Computational Biology and Bioinformatics
Rap1 is key protein in regulating a cell signaling pathway that controls cell adhesion to its environment. Being able to manipulate and shutdown this pathway would yield immense benefits for…
Computational Biology and Bioinformatics
As medication in Middle Eastern countries is delivered to consumers in their original factory box, fraud where expired medicine is commercialized has become a typical issue. A novel mechanis…
Computational Biology and Bioinformatics
The purpose of this research was to create a new non-invasive test that could detect food based non-IgE mediated food allergies using saliva and antigens. A convenience sample of four indivi…
Computational Biology and Bioinformatics
Second Award
The human genome contains upwards of 20,000 genes that code for functional products, such as proteins. In addition to genes, the genome encodes regulatory elements that respond to specific s…
Computational Biology and Bioinformatics
Fourth Award
Mutations in the MeCP2 gene are the most common cause of Rett Syndrome (RTT), a severe form of autism diagnosed primarily in girls. The MeCP2 gene product, MeCP2, is a transcriptional regula…
Computational Biology and Bioinformatics
Cell locomotion and cell aggregation are part of the large blank areas in our biological knowledge today. Many scientists focus on targeting cancer with different compounds. However, Gliobla…
Computational Biology and Bioinformatics
In eukaryotes, the export of mRNA from the nucleus to the cytoplasm via the nuclear pore complex is an essential step in the gene expression pathway. Although the role of nucleoporins in nuc…
Computational Biology and Bioinformatics
Fourth Award
Nanotechnology has played a significant role in modern medical application. Nanocarriers are able to deliver the chemotherapeutic drugs and deliver them specifically to the targeted cells. A…
Computational Biology and Bioinformatics
Liquid Organic Hydrogen Carriers (LOHCs) are one of the most promising concepts for a new alternative renewable energy source. LOHCs are chemical compounds in which large amounts of hydrogen…
Computational Biology and Bioinformatics
Pulmonary Lymphangioleiomyomatosis (LAM) is a rare progressive, often-fatal lung disease associated with a mutation in either a TSC1 or TSC2 gene. LAM is manifested in three forms: slow-deve…
Computational Biology and Bioinformatics
About a decade ago it was discovered by Italian scientists that the Briggs-Rauscher oscillating reaction is sensitive to antioxidants. These free-radical scavengers inhibit the reaction; the…
Computational Biology and Bioinformatics
With the world population increasing by 60 million every year, the search for clean water becomes a growing concern especially in Less Economically Developed Countries (LEDCs). Waste of anim…
Computational Biology and Bioinformatics
Neuroblastoma is an aggressive pediatric cancer, with two thirds of all cases found in children ages five or younger. Current drugs cause adverse side effects which greatly affects the devel…
Computational Biology and Bioinformatics
Chloramines have been used to disinfect potable water because they do not product carcinogenic DBP’s like traditional free chlorine. However, chloramines have been linked with lead leaching…
Computational Biology and Bioinformatics
Second Award
One in eight women will be diagnosed with a form of noninvasive Breast cancer during her lifetime. NEK2 is a highly-expressed gene in Breast cancer. The objective was to determine the role N…
Computational Biology and Bioinformatics
The adult muscle has stem cells called satellite cells. Those cells are quiescent in a normal situation and they get activated after injury. The most important function of satellite cells is…
Computational Biology and Bioinformatics
Cell culture is challenging due to the use of medium components such as fetal bovine serum and human serum, risk of transmission of microbial disease, allergies, and ethical issues. Thus, id…
Computational Biology and Bioinformatics
This experiment analyzed the effects of solute concentration on the optical rotation of various chiral molecules by building a polarimeter to measure their angle of rotation and comparing th…
Computational Biology and Bioinformatics
Eye-color genotypes are good predictors of eye-color phenotypes. The purpose of this project was to go the other direction and see if eye-color genotypes could be predicted based on eye-colo…
Computational Biology and Bioinformatics
New evidences have revealed that the protozoan parasite Plasmodium falciparum uses a communication net based on the releasing extracellular vesicles from infected red blood cells. The conten…
Computational Biology and Bioinformatics
Virus production is a limiting factor in fields that utilize viral platforms, including the fields of vaccinology, oncolytic virology, and gene therapy. Previous research has suggested that…
Computational Biology and Bioinformatics
The purpose of this study was to screen several VHH nanobodies for effective intracellular binding to a-Synuclein (Syn), whose aggregation is associated with Parkinson’s disease. Previously,…