Computational Biology and Bioinformatics
Epilepsy is one of the most common neurological disorders worldwide, and the unpredictable nature of epileptic seizures makes life challenging for many patients. The objective of this study…
Computational Biology and Bioinformatics
My research identifies novel ways to predict recurrence in triple-negative breast cancer patients. I used multiplexed ion beam imaging to analyze cell prevalence and protein expression in th…
Computational Biology and Bioinformatics
When the conscious mind declares a movement in the body, the central nervous system carries a signal to the muscles by way of neurons. This signal causes the muscles to contract in the form…
Computational Biology and Bioinformatics
Of the over 100 types of cancers that together claim 2,000 lives in the United States daily, neuroblastoma is the most common in children under the age of two. This project seeks to identify…
Computational Biology and Bioinformatics
Abnormally stiff brain tissue is associated with neural damage and can indicate Alzheimer’s dementia, other dementias, and normal pressure hydrocephalus. Currently, early Alzheimer’s diagnos…
Computational Biology and Bioinformatics
This experiment sought to determine if individuals with schizophrenia have observable differences in the genetics of their oral microbiomes compared to healthy individuals. This was done by…
Computational Biology and Bioinformatics
The purpose of the project was to create a brain-computer interface headset prototype capable of allowing patients with motor impairments and paralysis to regain a range of mobility utilizin…
Computational Biology and Bioinformatics
Computational modeling offers a powerful method for studying cause-effect relationships in biology. This is immensely valuable for creating synthetic biomimicry structures. Mimosa pudica is…
Computational Biology and Bioinformatics
Third Award
Plant field testing proves often a long and costly process crucial to the development of efficient agricultural techniques. We aimed to create a plant topology simulator that presents a sign…
Computational Biology and Bioinformatics (inferred)
“Thought-Code”/” Blink-Code” Part II: Analyzing EEGs through dimensionality reduction for EEG classification Sarvesh R. Babu duPont Manual High School Abstract The focus of the project is to…
Computational Biology and Bioinformatics
The 2.4-fold increase in thyroid cancer over recent decades and variation across regions indicate that environmental factors may be influencers, including I-131 released during nuclear testi…
Computational Biology and Bioinformatics
Antibiotics can be used to cure bacterial infections. Antibiotics target various structures and processes within the cell such as protein synthesis, cell membrane integrity and cell wall syn…
Computational Biology and Bioinformatics
Third Award
A plummet in the research productivity of drug discovery has been observed in recent decades, with higher costs, longer timelines, and lower success rates of drug candidates in clinical tria…
Computational Biology and Bioinformatics
Around the globe, G6PD enzyme deficiency is one of the widely-encountered diseases. There are more than 140 variants but the Mediterranean variant is commonly seen in the world. Therefore, t…
Computational Biology and Bioinformatics
Approximately 20,000 different human proteins exist to perform specific tasks within a cell’s organelles focused on building, repairing, and giving signals needed for the body to survive. Ho…
Computational Biology and Bioinformatics
Precision medicine, or personalized medicine, is the most promising direction for treating complex diseases, such as cancer. The deadliest solid cancer, Pancreatic Ductal Adenocarcinoma (PDA…
Computational Biology and Bioinformatics
Dengue Fever is a debilitating viral disease of the tropics, transmitted by female Aedes mosquitoes, causing sudden fever, acute pains in the joints and hemorrhaging. The World Health Organi…
Computational Biology and Bioinformatics
The accurate age estimation is a substantial part of the integral biological profile, but quite complex in cases of unidentified decomposed and skeletonized human remains, especially in adul…
Computational Biology and Bioinformatics
With increasing interest in using fMRI and functional connectivity networks to understand and diagnose neurodegeneration, advanced method for image processing are necessary to produce highly…
Computational Biology and Bioinformatics
Spatiotemporal modelling is important in understanding communicable disease progression dynamics and evaluating public health intervention strategies. However, existing spatiotemporal models…
Computational Biology and Bioinformatics
Third Award
According to UNICEF, Kenya has a very high prevalence of child mortality rate which is approximately 49/1000 live births. In 2017 Kenya had an estimated 502,860 children who had missed the r…
Computational Biology and Bioinformatics
Transcription is the first, decisive phase of the genome expression. Genome transcription (when, where and how) is regulated by RNA polymerases, transcription factors and promoters. Protein…
Computational Biology and Bioinformatics
In brain research, an important step after staining and imaging the different brain cells is their phenotyping. In this research, we work with patches of images, taken with CLARITY and aim t…
Computational Biology and Bioinformatics
Fourth Award
MicroRNAs (miRNAs) are small noncoding RNA molecules that are implicated in many gene expression pathways. Because they can degrade genes before translation, they have been extensively resea…
Computational Biology and Bioinformatics
Time resolved X-ray crystallography produces molecular movies of proteins at femtosecond resolution. The elucidation of an enzyme’s structural dynamics during its catalysis has major implica…
Computational Biology and Bioinformatics
EEG (electroencephalogram) based identification systems have a myriad of applications ranging anywhere from scalable EEG systems for disease diagnostics, anti-epileptic drug administration,…
Computational Biology and Bioinformatics
Artificial Intelligence (AI) is the science of creating machines that can perform tasks which normally require human abilities (e.g. visual perception, speech recognition, decision-making).…
Computational Biology and Bioinformatics
Amyloid fibrils are small or slender fibers that can be found all around the human body and are formed by misfolded proteins. These fibers are resistant to degradation and can cause many dis…
Computational Biology and Bioinformatics
Third Award
Studying B cell receptor (BCR) binding is crucial for understanding how the human adaptive immune system attacks cancer cells – information that can translate into targeted and more efficaci…
Computational Biology and Bioinformatics
Fourth Award
DNA-binding proteins play an especially important role in regulating gene expression. These proteins called transcription factors (TFs) recognize and bind to DNA-sequences called DNA motifs,…