Browse real student projects, abstracts, and awards.
ISEF · 2021
Computational Biology and Bioinformatics Second Award
Progressive neurodegenerative disorders that are defined when a protein, called tau, builds up abnormally in a patient’s brain are called tauopathies. Breakthrough research has led to the id…
ISEF · 2021
Computational Biology and Bioinformatics
This project was outlined to identify important socio-economic variables and their influence in COVID-19 spread. This information can be beneficial to minimizing virus spread as it’ll allow…
ISEF · 2021
Computational Biology and Bioinformatics
Lung cancer is the leading cause of cancer mortality globally, made particularly deadly by asymptomatic metastasis in the early stages of cancer development. A solid understanding of the dyn…
ISEF · 2021
Computational Biology and Bioinformatics
Purpose: To analyze the effect of strict measures on the control of COVID-19 pandemic in China and elaborate its significance and enlightenment. Procedure: We collected epidemiological infor…
ISEF · 2021
Computational Biology and Bioinformatics
Aging is traditionally thought to be caused by complex and interacting factors such as DNA methylation. The traditional formula of DNA methylation aging is based on linear models and few wor…
ISEF · 2021
Computational Biology and Bioinformatics
After the age of 40, humans start to lose height when aging. Height loss is usually attributed to the decrease of upper-body length caused by vertebral compression, but clear evidence to sup…
ISEF · 2021
Computational Biology and Bioinformatics
The issue of food waste is a major problem that contributes to the emissions of greenhouse gases into the environment in addition to causing illness in humans. This experiment aimed to devel…
ISEF · 2021
Computational Biology and Bioinformatics
Title: Through the Looking Glass: Uncovering the Molecular Mechanisms of Phytochemical Treatment for the Prevention Age-Related Macular Degeneration Name: Rishab Samant School: Vestavia Hill…
ISEF · 2021
Computational Biology and Bioinformatics
Ulcerative colitis (UC) and type 2 diabetes (T2D) are associated with high risks of colorectal cancer (CRC), yet bacterial biomarkers for CRC present in both remain unclear. In this study, a…
ISEF · 2021
Computational Biology and Bioinformatics
The purpose of this experiment is to demonstrate the effect of safety mask usage on the infection and mortality rates of a simulated airborne pathogen. The results should reflect the effects…
ISEF · 2021
Computational Biology and Bioinformatics
Phosphofructokinase-1 (PFK-1) is an allosteric enzyme in glycolysis that regulates the ATP-dependent phosphorylation of fructose 6-phosphate (F6P) into fructose 1,6-bisphosphate (FBP). In ca…
ISEF · 2021
Computational Biology and Bioinformatics
Prostate cancer is the most common cancer in men in the United States. Death in prostate cancer patients is often related to medical conditions other than prostate cancer itself. Hence, it i…
ISEF · 2021
Computational Biology and Bioinformatics Third Award
P38 alpha (MAPK 14) is a protein kinase implicated in the pathological mechanisms of myofibrillar myopathy, cancers, and inflammatory diseases like Alzheimer’s and rheumatoid arthritis. Alth…
ISEF · 2021
Computational Biology and Bioinformatics Second Award
This research presents a novel machine-learning approach for the identification of potential treatments against SARS-CoV-2, the causative pathogen of COVID-19. Despite the existence of effec…
ISEF · 2020
Computational Biology and Bioinformatics
Epilepsy is a chronic brain disorder impacting over 65 million people globally. Each year, >100000 patients die from Sudden Unexpected Death in Epilepsy (SUDEP), many from fatal falls. A rel…
ISEF · 2020
Computational Biology and Bioinformatics
Disease-disease correlations lend to improved treatment modalities, however, current disease-disease correlation databases fail to include poorly-studied diseases. Craniosynostosis, despite…
ISEF · 2020
Computational Biology and Bioinformatics
Gene expression is regulated by proteins known as transcription factors, which bind to specific DNA sequences called enhancers. Enhancers activate nearby genes, but there is still a limited…
ISEF · 2020
Computational Biology and Bioinformatics
As pollution levels rise, the relationship between pollutant degrading proteins across various organisms is vital to create a synthetic microbe that mitigates substance toxicity. To understa…
ISEF · 2020
Computational Biology and Bioinformatics
Dengue Fever is the most rapidly spreading mosquito-borne disease, with more than 25,000 deaths annually. To date, no vaccine has been developed for Dengue Fever due to the existence of four…
ISEF · 2020
Computational Biology and Bioinformatics
Acute Myeloid Leukemia (AML) is a deadly blood cancer in which abnormal blast cells crowd out healthy blood cells in bone marrow. Although AML is the most common adult leukemia, its survival…
ISEF · 2020
Computational Biology and Bioinformatics
Deep Neural Networks (DNNs) have successfully demonstrated superior overall performance in many image classification and recognition tasks on H&E histology images. Reported studies typically…
ISEF · 2020
Computational Biology and Bioinformatics
Artificial intelligence has been used to identify cancer types with high accuracy, but despite this, we see increased death rates in cancer. Even though cancer is a complex and extremely het…
ISEF · 2020
Computational Biology and Bioinformatics
In 2015, 13,000 Louisiana residents died of heart disease. Due to expensive cost of ECG analysis, underrepresented community people cannot get medical supports. There are challenges on medic…
ISEF · 2020
Computational Biology and Bioinformatics
[Problem] For individuals with hearing loss, distinguishing between various voices in noisy environments is difficult. Current hearing aids are unable to identify and attenuate background vo…
ISEF · 2020
Computational Biology and Bioinformatics
Cancer is something we hear in our everyday lives, it takes friends and loved ones and there seems like there is no help for them, especially when the treatment does not work. Through this p…
ISEF · 2020
Computational Biology and Bioinformatics
The student researcher tested for correlation between protein type and fatality rate in Zaire ebolavirus, hypothesizing that there is a significant difference in the fatality rates due to pr…
ISEF · 2020
Computational Biology and Bioinformatics
In our project, we sought to use machine learning to generate new lead molecules and expedite drug discovery. Lead molecules are molecules with an affinity for inhibiting the target protein,…
ISEF · 2020
Computational Biology and Bioinformatics
Cardiovascular malformations are the most common type of birth defects. Congential HeartDisease occurs in approximately 1% of all births globally and has a 48.1% infant mortality rate. Given…
ISEF · 2020
Computational Biology and Bioinformatics
Comparison of methods used to diagnose Alzheimer’s Disease (AD) via imaging, mental, and genetic data remains an open area of investigation. In this investigation, it was hypothesized that a…
ISEF · 2020
Computational Biology and Bioinformatics
Major depressive disorder (MDD) is a debilitating illness, and antidepressant treatment often yields inadequate response rates. It is not currently understood why antidepressant response rat…