38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2021
Computational Biology and Bioinformatics
Current processes of drug discovery are too long, expensive, and ineffective. Companies undergo years of research and development without the certainty of obtaining conclusive results. Drug…
ISEF · 2021
Computational Biology and Bioinformatics Third Award
Scoliosis is a condition of abnormal spinal curvature with approximately 60,000 U.S. pediatric patients undergoing surgery or being placed into braces each year. Skeletal maturity assessment…
ISEF · 2021
Computational Biology and Bioinformatics
Cancer threatens millions of individuals every year and remains a central issue in the scientific community. It’s important to search for new alternative treatments, and anticancer peptides…
ISEF · 2021
Computational Biology and Bioinformatics
Cancer is a leading cause of human death worldwide, yet quick and accurate identification of the primary cancer site is still lacking. Owing to its ability to differentiate similar tumors an…
ISEF · 2021
Computational Biology and Bioinformatics Fourth Award
Current techniques of target identification in drug development are costly, lengthy, and function with high degrees of uncertainty that a drug can succeed in modulating a target. To address…
ISEF · 2021
Computational Biology and Bioinformatics
Seizures, sudden bursts of electrical activity in cortical neurons, occur frequently in neonates (1-28 days old) and are a common emergency in the NICU. Timely and proper treatment is crucia…
ISEF · 2021
Computational Biology and Bioinformatics
Wolbachia, a species of endosymbiotic intracellular bacteria found in a diverse set of species, is most notable for its role in vector control strategies to reduce the spread of diseases tha…
ISEF · 2021
Computational Biology and Bioinformatics
To limit the spread of COVID-19, government policies are necessary. Current research focuses primarily on documenting proposed policies rather than assessing the efficacy of said proposals.…
ISEF · 2021
Computational Biology and Bioinformatics
In this work, I studied cas9 protein, one of the proteins of the CRISPR-Cas bacterial defense system. It was chosen because a genome editing system based on it is currently under development…
ISEF · 2021
Computational Biology and Bioinformatics Fourth Award
Alzheimer’s Disease is a progressive neurodegenerative disease that results in memory loss and a general cognitive decline, afflicting approximately 45 million people worldwide with the rate…
ISEF · 2021
Computational Biology and Bioinformatics
Melanoma is one of the most fatal forms of skin cancer and is often very difficult to differentiate from other benign skin lesions. However, if detected at its early stages, it can almost al…
ISEF · 2021
Computational Biology and Bioinformatics Fourth Award
In recent decades, there's been an alarming increase in bacterial evasion of antibiotic treatments, necessitating an improved understanding of resistance, tolerance, and persistence. Resista…
ISEF · 2021
Computational Biology and Bioinformatics
Early detection and treatment of colorectal cancer is vital to prevent metastasis, but past models lack a cohesive pipeline from diagnosis to treatment to determine biomarkers and suggest tr…
ISEF · 2021
Computational Biology and Bioinformatics
If adjacent genes in the same direction (Tail-to-Head, T2H) are located very close to each other (at a distance of several hundred base pairs) or partially overlapping, chimeric transcripts…
ISEF · 2021
Computational Biology and Bioinformatics
As of April 9th, 2021, there have been over 31 million cases of COVID-19 in the United States alone. Simultaneously, an estimated 15% of U.S. adults suffer from Chronic Kidney Disease (CKD).…
ISEF · 2021
Computational Biology and Bioinformatics Fourth Award
My project aims to identify a therapy to treat COVID-19 infections using gene expression and a computer-assisted approach. My computer program, AMiF (Augmented miRNA Filtration Model) works…
ISEF · 2021
Computational Biology and Bioinformatics
With major outbreaks in over 150 countries, the COVID-19 pandemic has had a devastating effect on public health, daily life, and the global economy. Absent a vaccine or therapeutic treatment…
ISEF · 2021
Computational Biology and Bioinformatics
While pancreatic cancer is a deadly disease that is difficult to diagnose at an early stage, early diagnosis yields a much higher survival rate, making it key for treatment. With an increase…
ISEF · 2021
Computational Biology and Bioinformatics
Influenza virus is a single-stranded negative RNA virus, divided into three types, A, B, and C (Shao, Li, Goraya, Wang, & Chen, 2017). This research focused on influenza type A, which mainly…
ISEF · 2021
Computational Biology and Bioinformatics Third Award
Despite major advances in immunosuppression, thousands of transplanted organs are still rejected, endangering the lives of many patients. Traditional approaches to understanding transplant r…
ISEF · 2021
Computational Biology and Bioinformatics
Background: Alzheimer’s Disease pathogenesis is associated with the deposition of amyloid-beta (AB) protein aggregates in the brain. No treatment has been proposed to degrade pre-oligomeric…
ISEF · 2021
Computational Biology and Bioinformatics
Vestibular schwannomas, also known as acoustic neuromas, result from an overproduction of schwann cells on the eighth cranial nerve. This benign brain tumor affects hearing and balance. Data…
ISEF · 2021
Computational Biology and Bioinformatics
To research the spread of the novel coronavirus, and prevent and control the widespread of the virus, this project investigated the spread of the novel coronavirus pneumonia epidemic from th…
ISEF · 2021
Computational Biology and Bioinformatics
The purpose of this experiment is to discover how the percent of animals marked and the sample size affects the accuracy of the capture-recapture method. To simulate if the percent of marked…
ISEF · 2021
Computational Biology and Bioinformatics Second Award
Multiple Sclerosis (MS) is a neuroinflammatory demyelinating disease that affects over 2,000,000 individuals worldwide. Although the exact etiology of the disease is unknown, the main sympto…
ISEF · 2021
Computational Biology and Bioinformatics
During the initial spread of COVID-19, countries varied in their ability to control the virus. Science shows this variability is in part due to sociocultural factors. One sociocultural facto…
ISEF · 2021
Computational Biology and Bioinformatics Fourth Award
The goal of this project was to construct a working RNA-sequencing analysis pipeline that would (1) produce visuals to demonstrate differentially expressed genes via PCA plots, correlation a…
ISEF · 2021
Computational Biology and Bioinformatics
Mutations on the SARS-CoV-2 spike protein have gained increasing attention. However, its mutation pattern in different geographic locations within a country has not been investigated. In thi…
ISEF · 2021
Computational Biology and Bioinformatics
Bainbridge-Ropers Syndrome is a rare autosomal dominant neurodevelopmental disease characterized by predicted truncating mutations in the ASXL3 gene. Around 200 children have been diagnosed…
ISEF · 2021
Computational Biology and Bioinformatics
Dementia is a disease that impairs the brain it causes memory loss and interferes with a person’s ability to think and make judgments. Every year 10 million people get diagnosed with dementi…