ISEF · 2018
Temperature Insulating Solution
Chemistry
Studies show that in the US alone, around 742 children have died due to paediatric vehicular heatstrokes since 1998. Around 42 of the deaths occurred in 2017, the highest temperature being 4…
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ISEF · 2018
The Agricultural Application of Phytomethylotrophy
Biochemistry
Methylotrophy is the means of obtaining nutrition via the assimilation of single-carbon compounds. It is employed as a sole means of nutrition by many bacteria; however, the enzymes used in…
ISEF · 2018
The Biochemical Interactions of Cardiac Ion-Blocking Agents and Optical Coherence Tomography in vivo for Cardiovascular Diseases
Biochemistry First Award
Optical Coherence Tomography (OCT) is a novel 3D-imaging modality, however there has been limited research utilizing OCT to study physiological impacts of ion-blocking drugs, namely Class I,…
ISEF · 2018
The Color of An Azo Dye - A Combined Experimental and DFT Investigation of Spectral Properties of 5-(4-Sulfophenylazo) Salicylic Acid
Chemistry
A study of the azo compound Mordant Yellow 10 (5-(4-sulfophenylazo)salicylic acid) was conducted, aiming to investigate factors contributing to its observed color. The compound was synthesiz…
ISEF · 2018
The Development of Biligand Inhibitors and Non-Radioactive Inhibition Assay for Protein Kinase Aurora B
Biochemistry
The goal of given project was to synthesize and biochemically characterize a new class of compounds that could report and block the abnormally elevated activity of Aurora B. The compounds re…
ISEF · 2018
The Difference in the Energy Release of Lipids vs. Carbohydrates Based on Their Chemical Structure
Biochemistry
This project was put forward in an effort to distinguish how the chemical structures of lipids and carbohydrates affect the amounts of energy released when heat ruptures the bonds holding to…
ISEF · 2018
The Effect of Natural Chitosan on the Removal of Azo Dyes from Water
Chemistry
The purpose of this experiment was to determine if the properties of chitosan were significant factors in removing Azo dye from solution. Congo Red – a dangerous azo dye – is commonly found…
ISEF · 2018
The Effect of Nonassociative Learning on Oxidative Stress in Caenorhabditis elegans: A Potential Application for Alzheimer’s Disease Research
Biochemistry Third Award
Alzheimer’s disease results in learning and memory deficits due to toxic changes in the brain caused by amyloid-ß plaques and oxidative stress (Alzheimer’s, 2011). Oxidative stress is caused…
ISEF · 2018
The Effect of Ocean Acidification on Native Oyster Reproduction and Larval Development
Biochemistry Fourth Award
The native Olympic Oyster, Ostrea lurida, once populated the pays on the Pacific Coast. During the California Gold Rush, these oysters were harvested to the extent that they disappeared from…
ISEF · 2018
The Effects of Alkaline and Acidic Substances on Catalase Functionality and Molecular Structure
Biochemistry
The disposal of hydrogen peroxide is crucial for organismal health as hydrogen peroxide is a toxin that causes necrosis, apoptosis, gangrene, ulcers, susceptibility to other medical conditio…
ISEF · 2018
The Effects of Exercise on Cognitive Impairment due to Metabolic and Epigenetic Dysregulation
Biochemistry
The purpose of this experiment was to test whether exercise could mitigate neuroinflammation, epigenetic dysregulation, and memory loss caused by high-fat diet. Diets high in fat cause decre…
ISEF · 2018
The Fabrication of Flexible Transparent Electrode Based on Silver Nanowires
Chemistry
With the rapid development of touch devices such as display screens, photovoltaic cells and organic light-emitting diodes (OLEDs), there is a growing demand for transparent conductive electr…
ISEF · 2018
The Filter for Dynamic Purification of Water from Oil Products
Chemistry
Petroleum derived products have the potential to cause an enormous harm to the biosphere and removal of these products from the ground water and run-off water presents one of the most critic…
ISEF · 2018
The Impact of Fullerene Additives on the Morphology of P3HT Thin Films Processed From Binary Solvent Mixtures
Chemistry
The effect of various solution preparation methodologies on the aggregation of P3HT is studied. The aggregation of P3HT was induced by the use of a chloroform:dichloromethane binary system a…
ISEF · 2018
The Influence of Citric Acid on Bacterial Growth
Biochemistry
We asked ourselves what the influence of citric acid on bacterial growth would be and at which concentration the solution would be lethal to a certain bacterium. We assumed that Escherichia…
ISEF · 2018
The Polar Compound Measuring Tool Referred from the Frying Oils Viscosity
Chemistry
The objective of this project was to develop the polar compounds measuring tool referred from the frying oils viscosity. The relationships between the polar compounds content in reused fryin…
ISEF · 2018
The Power of Nature
Chemistry
It has been decided to work on increasing the efficiency of cement because cement has many applications and its efficiency is crucial. Moreover, decreased efficiency of cement can undermine…
ISEF · 2018
The Role of Autotaxin-LPA-LPP3 Axis in Ischemic Stroke
Biochemistry Fourth Award
Ischemic stroke is one of the leading causes of death and permanent disability. Blood- brain barrier (BBB) disruption greatly contributes to ischemic brain damage. Lysophosphatidic acid (LPA…
ISEF · 2018
The Role of Sarcolipin Protein on Energy Expenditure and Obesity Prevention
Biochemistry
Obesity is a major problem in the United States, affecting over one-third of the U.S. adult population. The best solution to this problem is to exercise, however, this method is difficult fo…
ISEF · 2018
The Synthesis and Characterization of Novel Heteroleptic Alkaline Earth Metal Compounds
Chemistry
Metal Organic Chemical Vapor Deposition (MOCVD) precursors have properties that are beneficial in creating mixed-metal electronic thin-film materials such as ferroelectric SrBi2Ta2O9 and sup…
ISEF · 2018
TiO2 Hollow Shell Around Gold Nanoparticles- A More Efficient Photocatalyst
Chemistry
Objective: Synthesize gold nanoparticles (AuNPs) surrounded by a titania (TiO2) hollow shell to serve as a more efficient photocatalyst. Method: The AuNPs were prepared by mixing the gold pr…
ISEF · 2018
Tree Plaster - Using of Polymers as a Drugs Release Media to Cure Wood Decay Fungi
Chemistry Third Award
Problems caused by wood decay fungi have been a potential problem to the environment and society. Therefore, a novel drug delivery system, named “Tree Plaster”, has been developed to treat p…
ISEF · 2018
Uncovering the Hidden Defense Mechanisms of Flaviviruses
Biochemistry Third Award
Flaviviruses, such as the Zika and Dengue virus, are positive-sense, single-stranded RNA viruses that have caused widespread epidemics and morbidity throughout the world. Little is known abo…
ISEF · 2018
Use of Electrochemical Advanced Oxidation Processes for Novel Treatment of Sludge and Wastewater
Chemistry First Award
Farms in Singapore are encouraged to harness technology to optimise food production. Currently, local farms produce 26% of eggs consumed in the nation. While we address food security needs,…
ISEF · 2018
Water Free of Lead and Mercury
Chemistry
In Jordan water shortage is a serious problem that is getting worse because several major water resources became contaminated with heavy metals from industrial waste, like King Talal Dam. Th…
ISEF · 2018
Will Fluorescent Dyes Be Able to Detect the Saccharide D-galactose on Parasites, such as Trypanosoma cruzi?
Chemistry
The research project’s purpose is to use fluorescent dyes to identify the outer coatings of parasites, aiding vaccine development. Depending on the change in the spectrum, the glycoprotein w…
ISEF · 2017
An Achilles Heel in Oncogenic Ras
Biochemistry
Mutations in the genes encoding Ras GTPases are major drivers of human cancers. Despite 30 years of intensive research, no compounds directly targeting Ras proteins have been developed. Prev…
ISEF · 2017
An Analysis of Bisphenol-A, Bisphenol-S, Bisphenol-F in BPA-Free versus Ordinary Plastic Containers Using Gas Chromatography Mass Spectrometry
Chemistry
Plastic bottles are manufactured with organic epoxy resins containing Bisphenol A (BPA), Bisphenol S (BPS), and Bisphenol F (BPF). These are carcinogenic and mutagenic substances. People ass…
ISEF · 2017
A New & Low Cost Technology of Electrochemical & Bionic Sensors
Chemistry
In present days electrochemical sensors are used to detect some gases and compounds. These sensors use noble metals. So, these sensors are expensive and do not detect multiple compounds and…
ISEF · 2017
An "Organic" Organic Project: The Design of a Sustainable, Cost-Efficient, Multistep Project Beginning with the Teaberry Plant Utilizing the Fundamental Techniques of Organic Chemistry to Synthesize Aspirin
Chemistry
Environmental health and sustainability are major concerns for the twenty-first century. Therefore, this project was designed to create a sustainable, cost-efficient multi-step procedure tha…