Browse real student projects, abstracts, and awards.
ISEF · 2025
Biochemistry
Carrizo Cane, an invasive species affecting the health of Webb County's Rio Grande River and other southern U.S. waterways, presents significant ecological challenges. Instead of focusing on…
ISEF · 2025
Biochemistry
Oligonucleotides, especially siRNAs, have been identified as a point of interest due to their capability for precision targeting of "undruggable" targets. siRNAs (Small Interfering RNA) bind…
ISEF · 2025
Chemistry
As the climate crisis demands cleaner and more efficient energy systems, hierarchically self-assembled nanostructures are emerging as promising tools for sustainable technologies. Hierarchic…
ISEF · 2025
Chemistry
Electrochemical CO2 reduction to C2 hydrocarbons has been intensively studied as a promising approach for utilizing CO2 emissions and meeting the high demand for ethanol and ethylene as valu…
ISEF · 2025
Chemistry
One common environmental activity at school is collecting and sorting old batteries for recycling. However, it is just the first step of the treatment process for lithium-ion batteries, whic…
ISEF · 2025
Chemistry
As global hydrogen demands reached 20 million tons in 2024, electrolysis "the chemical process of splitting water into hydrogen and oxygen" remains one of the most promising methods for clea…
ISEF · 2025
Chemistry
Hydrogen has emerged as a promising medium for zero-carbon energy storage; however, due to the cost and complexity of electrocatalyst synthesis for alkaline water splitting (AWS), approximat…
ISEF · 2025
Biochemistry
The tear-inducing chemical, or lachrymatory factor, syn-propanethial s-oxide, is released from onions when their cells are disrupted. The reaction creating this chemical is catalyzed by the…
ISEF · 2025
Biochemistry
Infertility affects over 186 million people globally and is mechanistically linked to oxidative stress-induced mitochondriopathy, genomic instability, and chronic inflammation. These patholo…
ISEF · 2025
Biochemistry
This project's aim was to identify the optimal pH (slightly acidic to neutral pH range: pH 5-pH7) at which the enzyme papain works efficiently in the digestion of the different protein subst…
ISEF · 2025
Biochemistry
Pancreatic Ductal Adenocarcinoma (PDAC) remains one of the most lethal cancers with a significantly low 5-year survival rate. PDAC is typically diagnosed in individuals over 65, suggesting t…
ISEF · 2025
Biochemistry
Pesticides are used in agriculture to deter plant pests and pathogens, but are known to have a detrimental effect on the environment and ecosystem because of their ability and frequency to k…
ISEF · 2025
Biochemistry
Despite being the sixth most fatal cancer worldwide, esophageal cancer is largely overlooked. The high mortality rate of esophageal cancer stems largely from its high metastatic capability.…
ISEF · 2025
Chemistry
When AgNO3 and sodium alginate are mixed, cross-linking occurs by the cation Ag+ and anion Cl-, which can produce an AgNPs-SA gel. Through this research, it was found out that when this film…
ISEF · 2025
Biochemistry
Nicotinamide mononucleotide (NMN), is a promising nutraceutical attracting much attention for its pharmacological and anti-aging efficacies. While NMN biosynthesis in Escherichia coli by met…
ISEF · 2025
Chemistry
Current thermal and electrochemical green conversion methods are unsustainably powered by fossil fuels, necessitating a greener approach. Consequently, Researchers have turned to phototherma…
ISEF · 2025
Biochemistry
In this study, microbial fuel cells (MFCs) of our own design were inoculated with organisms of the species Shewanella oneidensis. S. oneidensis is a gram-negative, flagellum-motile bacterium…
ISEF · 2025
Chemistry
Hydrogen is a promising clean energy carrier, yet current production methods remain either carbon-intensive or economically unsustainable. Recently, attention has shifted to serpentinization…
ISEF · 2025
Chemistry
Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals widely used in consumer products like non-stick cookware and food packaging since the 1950s. Due to their strong carbon-flu…
ISEF · 2025
Biochemistry
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are widely used medications to treat pain, fever, and inflammation. These drugs function by inhibiting Cyclooxygenase (COX) enzymes, specifical…
ISEF · 2025
Biochemistry
With rising mortality caused by breast cancer, it is necessary to develop early diagnostic techniques for rapid identification, prior to metastasis. Triple negative breast cancer (TNBC) make…
ISEF · 2025
Chemistry
This research, conducted during a paid summer internship through ACS Project SEED, focused on synthesizing and analyzing N-3-HPA for their potential use in seizure management. To develop eff…
ISEF · 2025
Biochemistry
Amyloid-ß (Aß) extracellular plaques in the brain are a primary cause of Alzheimer’s Disease. Previous studies have focused on understanding cerebral Aß production and prevention. However, n…
ISEF · 2025
Chemistry
Light is a promising alternative to traditional reagents for synthesis due to its reduced environmental toxicity, ease of control, and lowered cost. Moreover, photochemisty’s ability to crea…
ISEF · 2025
Chemistry
In our research we focused on antivirotics, broad-spectrum drugs against RNA viral diseases. Galidesivir, a molecule that today appears to be the most optimal inhibitor of viral RdRp, became…
ISEF · 2025
Biochemistry
At-home blood collection, such as the dried blood spots for fertility workups has been challenging due to low circulating Anti-Mullerian Hormone (AMH) concentrations and dependence on traine…
ISEF · 2025
Biochemistry
Ionizable lipid nanoparticles (LNPs) are the mainstream delivery mechanisms for mRNA therapeutics. pH-sensitive protonation allows their membranes to favorably (de)stabilize based on the sur…
ISEF · 2025
Chemistry
Over 350 million tons of plastic waste are produced annually while less than 10% is recycled. Through catalytic hydrogenolysis, plastic waste can be converted into diesel with strontium tita…
ISEF · 2025
Biochemistry
Biochemical signaling plays a key role in molecular pathways in various disease processes of women’s reproductive health. Polycystic Ovarian Syndrome (PCOS) affects 66 million reproductive-a…
ISEF · 2025
Biochemistry
Cancer patients have access to advanced drugs like biosimilars of trastuzumab, pertuzumab, and trastuzumab emtansine (T-DM1). However, continuous devleopment of new drugs is required to trea…