Browse real student projects, abstracts, and awards.
ISEF · 2026
Chemistry
The limitations of traditional CO2 capture technologies and the rapid rise in CO2 emissions necessitate efficient methods and materials for CO2 capture and conversion under mild conditions.…
ISEF · 2026
Chemistry
PFAS chemicals, or perfluorinated substances, are commonly found in household products, like non-stick cookware, waterproof materials, and fabrics. PFAS, or perfluorinated substances, are co…
ISEF · 2026
Biochemistry
Hypermobile Ehlers-Danlos Syndrome (hEDS) is a connective tissue disorder characterized by collagen disorganization and impaired extracellular matrix signaling (ECM), resulting in chronic jo…
ISEF · 2026
Chemistry
Counterfeit milk accounts for up to 14% of food fraud cases globally, severely impacting the economic, consumers health, and manufacturers reputation, particularly in solid-state milk produc…
ISEF · 2026
Chemistry
Introduction: The Cau Bay River is an important drainage waterway for the Long Bien-Gia Lam area (Hanoi). Effective water quality monitoring and real-time predictive modeling are critical fo…
ISEF · 2026
Biochemistry
In 2025, an estimated 2,041,910 new cases of cancer will be diagnosed in the United States, and 618,120 people will die from the disease (NIH, 2025). It is a leading cause of death worldwide…
ISEF · 2026
Chemistry
Various recent findings indicate that several tissues and muscles in the human body contain nano/micro-plastics; including the brain, acting similar to a sponge- absorbing the highest concen…
ISEF · 2026
Biochemistry
Cancer is a leading cause of death, posing a significant socioeconomic burden worldwide. Immune checkpoint inhibitors targeting PD-1/PD-L1 or CTLA-4 using monoclonal antibodies have brought…
ISEF · 2026
Biochemistry
Lateral flow immunoassays (LFIAs) are analytical tools used in many areas, especially in point-of-care diagnostics, and are best known as pregnancy tests and COVID-19 antigen tests. Conventi…
ISEF · 2026
Chemistry
Water pollution caused by organic dyes is one of the main environmental problems due to their toxic effects and persistence in aquatic environments. The purpose of this project was to develo…
ISEF · 2026
Chemistry
This study presents the development of multifunctional polyurethane (PU) composites combining flame retardancy, thermal insulation, and antimicrobial activity through the incorporation of ex…
ISEF · 2026
Biochemistry
Exocrine Pancreatic Insufficiency (EPI) is a disorder characterized by inadequate secretion of pancreatic enzymes, leading to malabsorption, nutrient deficiencies, and reduced quality of lif…
ISEF · 2026
Chemistry
Glioblastoma accounts for 50.1 percent of all primary malignant brain tumors. Tumor stem cells play a key role in treatment resistance and tumor recurrence, as they are capable of self-renew…
ISEF · 2026
Biochemistry
My project is DPPH: Antioxidant Properties of Tea, in which I tested to see if earl grey, jasmine, or chamomile tea had vastly different amounts of antioxidants, and if brewing time affects…
ISEF · 2026
Biochemistry
Drug repositioning—the repurposing of existing drugs for new applications—provides high safety but is still limited in gene therapy. As gene therapy research grows globally, safe genome engi…
ISEF · 2026
Chemistry
With the advancement of vaccine technology, the need for safe and effective adjuvants has become increasingly important. While QS-21 is a clinically established adjuvant, it alone cannot ful…
ISEF · 2026
Chemistry
The search for renewable energy sources is an important focus of modern research due to challenges such as climate change and the reduction of fossil fuels. Microbial fuel cells (MFCs) are c…
ISEF · 2026
Biochemistry
Contemporary studies have shown that alpha-synuclein oligomers may have a pivotal role in the pathogenesis of Parkinson's Disease (PD) by inducing cellular toxicity leading to dopaminergic n…
ISEF · 2026
Chemistry
Global carbon dioxide (CO2) emissions exceed 37 billion tons annually, intensifying climate change and motivating technologies that convert CO2 into valuable chemicals. Electrochemical CO2 r…
ISEF · 2026
Biochemistry
Breast cancer, the most common cancer in US women, accounts for approximately 32% of new diagnoses annually. Approximately 42,170 women will die from breast cancer in 2025. Current treatment…
ISEF · 2026
Chemistry
Metals tarnish due to oxidation reactions with their environment. While oxidation leads to corrosion, we don't fully understand how different metals corrode under the same conditions. This e…
ISEF · 2026
Chemistry
The traffic light reaction is a visual chemistry magic experiment that allows the observation of redox reactions. This reaction involves the blue dye indigo carmine (IC) being reduced by glu…
ISEF · 2026
Biochemistry
Alzheimer’s Disease is a neurodegenerative disorder characterized by the hyperphosphorylation of Tau and collapsin response mediator protein-2 (CRMP2), a newly identified and understudied bi…
ISEF · 2026
Biochemistry
Liver fibrosis is a global health crisis, affecting approximately 7.3% of adults worldwide. The disease is progressive, with advanced stages characterized by formation of a permanent extrace…
ISEF · 2026
Chemistry
Glioma is a brain tumor with a high mortality rate, partly because symptoms such as cognitive changes often emerge only after substantial tumor growth. CD44, a transmembrane protein overexpr…
ISEF · 2026
Chemistry
This study evaluates the feasibility of MnO2 as a transparent, cost-effective alternative to TiO2, the industry standard, in photocatalytic remediation and degradation of PET microplastics.…
ISEF · 2026
Chemistry
Mercury is a highly toxic heavy metal that poses a serious risk to human health and the environment, affecting an estimated 19 million people worldwide. In aquatic systems, inorganic mercury…
ISEF · 2026
Biochemistry
Three platinum anticancer compounds have been used for over 40 years in the United States. Despite their longtime use, it wasn't until 2017 that it was discovered that one of the platinum dr…
ISEF · 2026
Biochemistry
Breast cancer remains the most prevalent malignancy among women worldwide. Dose-dense AC-T chemotherapy (Adriamycin, Cyclophosphamide, and Paclitaxel), a commonly prescribed regimen, is asso…
ISEF · 2026
Biochemistry
Oligonucleotides, especially siRNAs, have been identified as a point of interest in recent research due to their capability for targeting of “undruggable” targets. siRNAs bind to and guide t…