Biomedical Engineering
10,000 of all known human diseases are monogenic, caused by a single mutation in the DNA. Scientists have tried developing the Zinc Finger Nuclease (ZFN) and Transcription Activator-like Eff…
Biomedical Engineering
Goal: To build a practical device capable of improving my vision by directing a controlled level of light into the eye (i.e. photoactivation.) Problem/Background: I have multiple eye conditi…
Biomedical Engineering
The regeneration of bone defects caused by trauma, fracture, and disease is a significant clinical challenge for both military and civilian patients in the United States and around the world…
Biomedical Engineering
Tissue-material integration is a key challenge of engineering medical implants and implantable biosensors. Implants often undergo an intense foreign body reaction orchestrated by human macro…
Biomedical Engineering
Chronic lung diseases are a serious world threat. According to the World Health Organization, there are approximately 364 million pulmonary disease patients around the world and this number…
Biomedical Engineering
Third Award
Acetabular labral tears comprise 22% of reported groin pain. Repairs involve suturing torn tissue to the bone via anchors, or removing inflamed tissue. Both prevent the body from healing nat…
Biomedical Engineering
Second Award
The Glasgow Coma Scale was proposed in the 1970s to classify the level of awareness of patients who have suffered some sort of traumatic brain injury (TBI). This scale is still used in hospi…
Biomedical Engineering
Fourth Award
While cancer starts as a single cell, termed cancer stem cell (CSC), the progeny CSCs are not created equal, but exhibit a spectrum of phenotypes of varying renewal capacities, metastatic po…
Biomedical Engineering
The prevailing identification and diagnosis of bacteria species requires the shipment of temperature-sensitive biological samples to a microbiology laboratory for biochemical, genetic or imm…
Biomedical Engineering
Objective: Stem cell-derived cardiomyocyte spheroids show enormous potential as cell delivery systems that improve cell retention and engraftment. Their survival post-transplantation in isch…
Biomedical Engineering
Cardiac Troponin I (cTnI) has been the ideal biomarker for myocardial infarction diagnosis in the past decade. In our experiment, we presented a new method for increasing the sensitivity of…
Biomedical Engineering
The recent Zika outbreak in over 48 countries has severe socioeconomic impact due to its damage to fetal brain development. Currently, Zika virus (ZIKV) is diagnosed with polymerase chain re…
Biomedical Engineering
Second Award
Diabetes currently affects over 346 million people worldwide and is one of the leading causes of death. Current treatment requires frequent blood-glucose tests followed by necessary insulin…
Biomedical Engineering
The prevention of concussion and sub concussive injury in helmeted activities are of great military, commercial, legal, and medical interest. A Summation of Tests for the Analysis of concuss…
Biomedical Engineering
In the United States, athletes suffer roughly 3.8 million concussions per year. Unfortunately, many current concussion diagnostics are subjective, placing athletes in potentially dangerous s…
Biomedical Engineering
Quantitative measurement of human gait is currently prohibitively expensive in the field of orthotics and prosthetics. This project is investigating the capabilities of a relatively inexpens…
Biomedical Engineering
DNA-sequenced engineering of protein nucleants may reduce limitations associated with protein crystallization and structure determination for structure-based drug development. This project i…
Biomedical Engineering
Spider silk is a very valuable but elusive material. It is 30 times tougher than steel yet is difficult to obtain. Synthetic production has had limited success because the chemical changes t…
Biomedical Engineering
Second Award
Early detection of bacterial pathogens is increasingly important in health care. Currently, the most common method to detect hemolytic bacteria in blood is culture testing. This method is ti…
Biomedical Engineering
Fourth Award
Realizing that the rehabilitation monitoring and correction devices for patients going under orthopedic surgeries of the lower limb are quiet trivial, we decided to tackle the subject and tr…
Biomedical Engineering
Respiratory diseases present a challenge to public health in both industrialized and developing countries due to their frequency, economic impact, severity and projected trends. Additionally…
Biomedical Engineering
60,000 domestic cases of Parkinson’s disease (PD) are diagnosed annually, while 7 million individuals have Essential Tremor (ET). My project provides simulation, diagnosis, and therapy to re…
Biomedical Engineering
First Award
Intracortical microelectrodes are essential tools in the rapidly growing brain-computer interface (BCI) and brain-machine interface (BMI) fields. The development of flexible intracortical mi…
Biomedical Engineering
Third Award
Parkinson’s disease is one of the most commonly seen neurodegenerative diseases. It has no cure and becomes worse over time. Parkinson’s symptoms often go unnoticed in early stages, leading…
Biomedical Engineering
The current methods used to kill and inhibit microbes though rapid and accurate, these methods involve the use of chemicals and antimicrobial drugs which are harmful and can lead to the deve…
Biomedical Engineering
Dental pulp stem cells (DPSCs) hold tremendous potential in regard to tissue and bone regeneration. This study evaluated the effects of nanoscale surface topography and cell-plating density…
Biomedical Engineering
The purpose of this research is to design and build an in-shoe fall detection system, as well as test the market for demand. The first phase of the project involved learning the Arduino lang…
Biomedical Engineering
The aim of this work is the creation of brain - computer interface for studies of human biorhythms. In the work conducted a unique experiment to determine frequency ranges of biorhythms in v…
Biomedical Engineering
Elevated levels of highly-reactive non-transferrin bound iron (NTBI) are common in many diseases with iron dyshomeostasis and are a marker of their progression. Chelation therapy is an effec…
Biomedical Engineering
Oral and intravenous methods of drug delivery distribute drugs systemically, resulting in low drug efficacy and side effects. Thus, polymeric nanocarriers that can target drug release in res…