Biochemistry/ Molecular Biology
Objectives/Goals Alzheimer's Disease (AD) is the leading cause of dementia and memory loss in adults. The disease presents itself through cognitive impairment. Dementia, memory loss, buildup…
Biochemistry/ Molecular Biology
Objectives/Goals The objective of this experiment was to identify changepoints in gene expression in the aging human brain and determine their role in the late onset of neurodegenerative dis…
Biochemistry/ Molecular Biology
Objectives/Goals In today's world, many instances of alcohol abuse and engagement are common and evident. There are various consequences of this behavior, ranging from a hangover the next da…
Biochemistry/ Molecular Biology
First Award
Objectives/Goals My objective is to find the type of rice with the lowest amount of starch for people who have diabetes. Methods/Materials Materials- Pressure cooker, jasmine rice, basmati r…
Biochemistry/ Molecular Biology
Objectives/Goals Current gene constructs need an effective mechanism able to maintain expression units in open chromatin configuration, both prohibiting cross talk between nearby promoters i…
Product Science (Biological) (Junior Division Only)
Third Award
Objectives/Goals After noticing differences in my glucose meter readings I was worried about their accuracy, so I chose to test blood glucose meter accuracy. My hypothesis was that blood glu…
Cellular and Molecular Biology
Oxidative damage in the genome occurs when reactive oxygen species (ROS), a byproduct of metabolism or from exogenous sources, come in contact with DNA. This has been suggested to play a rol…
Cellular and Molecular Biology
Gliomas are primary malignant tumors of brain and spinal cord with low survival without effective therapies. Annexin A1 (ANXA1) is a protein, which participates in proliferation, immune resp…
Cellular and Molecular Biology
The overuse of antimicrobials in many aspects of daily life has ushered in a wave of antimicrobial resistance to antibiotics that have been effective for decades. Resistance to antibiotics i…
Biochemistry/ Molecular Biology
Objectives/Goals Normally, the presence of Huntington's disease (HD) is marked by an aggregation (inclusion) of the diseased huntingtin protein, which is visible via standard electron micros…
Biochemistry/ Molecular Biology
Objectives/Goals Bisphenol A (BPA) is a plastic monomer used in nearly every form of plastic packaging. BPA is known to be an estrogen disruptor and imitator, which has massive potential imp…
Cellular and Molecular Biology
Nearly one in eight deliveries in the United States is preterm. Preterm birth has been correlated with oxidative stress, damage caused to cells by free radicals, in the uterine myometrium. O…
Biochemistry/ Molecular Biology
Objectives/Goals The objective of this study was to measure the content of Vitamin C in different conditions of fruits (dried, canned, and fresh) and determine which had the greatest content…
Cellular and Molecular Biology
The objective of this project was to characterize gal-7 as an antibiotic. The purpose of this research was to identify a model for glycan-specific antibiotics capable of reducing the risk of…
Cellular and Molecular Biology
Irreparable DNA lesions caused by radiation therapy induce apoptosis, a suicidal response that occurs in both cancerous and normal cells. Remarkably, mouse and human tissues in experiments t…
Cellular and Molecular Biology
Third Award
At first glance, diabetic kidney disease and cancer may seem to have little in common besides sharing high mortality rates. Diabetic kidney disease is a condition in which increased glucose…
Biochemistry/ Molecular Biology
Objectives/Goals The objective of my project was to determine the effect of the FGFR tyrosine kinase inhibitor AZD4547 on cell proliferation, induced apoptosis, and activated pathways in neu…
Product Science (Biological) (Junior Division Only)
Honorable_mention Award
Objectives/Goals Our project is to discover how to delay the decaying rate of a double reed? Double reeds, belonging to the bassoon and oboe, are delicate, short term lasting mouth pieces th…
Cellular and Molecular Biology
GATA4 is a transcription factor critical in the developmental process and early differentiation of the gastrointestinal tract. Studies using genetically modified mouse models have shown GATA…
Cellular and Molecular Biology
Human induced pluripotent stem cells (hiPSC) have a huge potential use in regenerative medicine. However, the mutant frequency of hiPSC reaches the level of differentiated cells rather than…
Cellular and Molecular Biology
Third Award
Metastatic breast cancer affects more than 250,000 people every year. Interactions of SOX transcription factors (TFs) and MALAT1 lncRNA may induce breast cancer metastasis. This study’s purp…
Biochemistry/ Molecular Biology
Objectives/Goals The purpose of the study was to analyze the sequence and structure conservation and identity of the vision protein, rhodopsin, across multiple species of ectothermic and end…
Cellular and Molecular Biology
Mechanisms involved in neuromuscular junction (NMJ) morphogenesis and active zone (AZ)-GluR receptor alignment are an active field of research in Drosophila neuroscience. I investigated four…
Biochemistry/ Molecular Biology
Honorable_mention Award
Objectives/Goals The major challenge in triple negative breast cancer (TNBC) therapy is to identify therapeutic targets to improve the efficacy and safety. Genomic instability generates abun…
Biochemistry/ Molecular Biology
Objectives/Goals The objective of my project was to figure out if Sequoia sempervirens, also known as coast redwood trees, from different locations were genetically diverse in one microsatel…
Biochemistry/ Molecular Biology
Objectives/Goals In my experiment, I extracted the invisible fat from foods such as potato chips, chocolate chips, and almonds and compared that value to its label to see which food had the…
Biochemistry/ Molecular Biology
Objectives/Goals My project aims to develop a simple Central Nervous System (CNS) Tumor test by investigating exosome expression profiles on the transcriptional and protein level for Medullo…
Biochemistry/ Molecular Biology
Objectives/Goals Interstitial cystitis (IC) is a serious bladder syndrome characterized by frequent urination, bladder discomfort, and pelvic pain. A potential systemic risk factor for IC is…
Cellular and Molecular Biology
Fourth Award
Abscission is the final stage of cytokinesis, the division of the cytoplasm between daughter cells, in which cells are physically separated by severing the intercellular bridge on either sid…
Cellular and Molecular Biology
The purpose of this project is to detect DNA damaging effect caused by various Aloe Vera extracts. A total of four Aloe Vera extract samples were tested using the Comet Assay. Three samples…