Cellular and Molecular Biology
Neurogenesis, the proliferation of neural cells in the brain, has been shown to correlate with higher rates of epileptogenesis (the progression of epilepsy in the brain). It has been shown t…
Product Science (Biological) (Junior Division Only)
Objectives/Goals The purpose of this science experiment was to determine if there were harmful bacteria in popular brands of dry, canned, and wet dog food. If dry, canned, and wet dog food a…
Cellular and Molecular Biology
Fourth Award
Squamous cell carcinoma (SCC) is an invasive type of skin cancer that lacks expression of lecithin-retinol acyl transferase (LRAT), a protein implicated in wound healing and cancer progressi…
Biochemistry/ Molecular Biology
Objectives/Goals The purpose of my project is to identify and quantify anti-cancer alkaloids in the invasive periwinkle, Vinca major. I tested if the habitat, presence of herbivory, or anato…
Biochemistry/ Molecular Biology
Third Award
Objectives/Goals The goal of this project is to take a novel approach to breast cancer metabolomics in order to reveal biomarkers with the potential to be used in a breast cancer diagnosis t…
Cellular and Molecular Biology
Allergies are an important health issue. We want to study the allergy signal cascade by characterizing IgE receptors in mast cells. Mast cells are immune cells. Our project focuses on an IgE…
Biochemistry/ Molecular Biology
Honorable_mention Award
Objectives/Goals Aging-delaying interventions often prevent multiple aging-related diseases (ARDs). My recent studies have characterized EZH2-mediated H3K27me3 as the first evolutionarily co…
Cellular and Molecular Biology
The purpose of this experiment was to identify molecular mechanisms involved with the regulation of the MAPT gene and the subsequent formation of neurofibrillary tangles in Alzheimer’s disea…
Biochemistry/ Molecular Biology
Objectives/Goals The objective is to determine which natural and nano-antioxidant are the most efficacious in Saccharomyces cerevisiae against oxidative stress. The natural antioxidants stud…
Cellular and Molecular Biology
Third Award
Every minute, a woman somewhere in the world will die of breast cancer. Despite significant advances in the field, breast cancer remains the leading cause of cancer death in women globally.…
Biochemistry/ Molecular Biology
Objectives/Goals The objective of this study was to identify a soluble growth factor secreted by endothelial cells, expression of which is normally suppressed by the presence of vascular end…
Cellular and Molecular Biology
Third Award
Vaccines are the one of greatest health innovations in human history, saving an estimated two million lives annually. They function by exposing the body to an antigen mimicking a pathogen an…
Biochemistry/ Molecular Biology
Objectives/Goals The objective of this project was to develop a diverse library of Light-Oxygen-Voltage sensing (LOV2) domain variants that could permit for more precise protein manipulation…
Product Science (Biological) (Junior Division Only)
Objectives/Goals The objective of this study is to determine which remedy would work best on skunk spray (n-Butyl mercaptan) to remove it's odor from fur. Methods/Materials Synthetic fur was…
Biochemistry/ Molecular Biology
Objectives/Goals The Mudgett laboratory hypothesized that WRKY transcription factors bind to the tomato DH1 promoter to regulate DH1 gene expression during pathogen infection and that XopD m…
Cellular and Molecular Biology
Although studies have found that inorganic arsenic (iAs), a potent carcinogen and estrogen-mimicking endocrine disruptor, is directly associated with prostate cancer incidence and mortality,…
Cellular and Molecular Biology
Infantile spasms (IS) is a neurological condition that generally initiates development of more severe forms of epilepsy along with developmental disabilities. An investigation of the role pl…
Product Science (Biological) (Junior Division Only)
First Award
Objectives/Goals My goal was to find the best environment to keep produce that usually goes bad quickly edible for long periods of time to save money, stop food waste, and help families use…
Cellular and Molecular Biology
Third Award
Metastasis accounts for ~90% of deaths from breast cancer (BC). This study aims to address the fundamental question of how cancer cells in the primary breast tumor become metastatic. CHD7 is…
Cellular and Molecular Biology
Astrocytes, the most abundant cell type in the central nervous system (CNS), have the vital role of keeping homeostasis in the brain. HIV infects the CNS early after primary infection and ca…
Cellular and Molecular Biology
Circular RNAs (circRNAs) constitute a class of relatively unstudied RNAs whose function is unknown. Recently, studies have shown that circRNAs are more abundant than previously recorded. The…
Biochemistry/ Molecular Biology
Objectives/Goals Circular RNAs (circRNAs) constitute a class of relatively unstudied RNAs whose function is unknown. Recently, studies have shown that circRNAs are more abundant than previou…
Cellular and Molecular Biology
Second Award
Genome editing technologies have revolutionized our ability to integrate foreign DNA sequences into cells with single nucleotide resolution. A major bottleneck of genome editing today is the…
Biochemistry/ Molecular Biology
Objectives/Goals The goal of the study was to find a method to detect the onset of Huntington's disease, HD, in its earlier stage. I hypothesized that by using FLIM (Fluorescence Lifetime Im…
Cellular and Molecular Biology
Overlapping polymerase chain reaction (O-PCR) is a common technique used in diverse fields to 'stitch' individual strands of DNA together. Previously, STITCHER was created to automate primer…
Biochemistry/ Molecular Biology
Objectives/Goals The objective of my study was to observe how Invertase changes the glucose concentration in foods when sucrose is present. Methods/Materials Tested the glucose concentration…
Cellular and Molecular Biology
First Award
It is evident that the tongue perceives tactile sensation, but little is known about the neurons that mediate this. Since tropomyosin receptor kinase C (TrkC) neurons are mechanoreceptors on…
Cellular and Molecular Biology
Chromosome movements during mitosis are orchestrated primarily by the interaction of spindle microtubules with the kinetochore, the site for attachment of spindle microtubules to the centrom…
Product Science (Biological) (Junior Division Only)
Fourth Award
Objectives/Goals I started doing research on the bark beetle when I found out about the blue stain fungus. Then my father asked me what stops the blue stain fungus? The answer was terpenes.…
Biochemistry/ Molecular Biology
Objectives/Goals The objective of this study is to determine whether varying the level of acidity in a steak marinade will affect the tenderness of a boneless beef top sirloin cap steak. Met…