Browse real student projects, abstracts, and awards.
ISEF · 2024
Cellular and Molecular Biology
Breast cancer is the most prevalent cancer among women. Endocrine therapy (ET) has been shown to be an effective treatment against estrogen receptor positive (ER+) breast cancer (BC); howeve…
ISEF · 2024
Cellular and Molecular Biology
200 million of the human population is affected by infertility—a disease that can develop in both men and women due to various reasons—which causes a decrease in the individuals reproductive…
ISEF · 2024
Cellular and Molecular Biology
Pancreatic Ductal Adenocarcinoma (PDAC) is a common type of pancreatic cancer and is characterized by a extremely high mortality rate. PDAC tumors tend to be extremely stiff, the reason for…
ISEF · 2024
Cellular and Molecular Biology
In recent decades CRISPR/Cas9 has emerged as a promising cancer treatment. Using CRISPR knockout plasmid to target the CDK11 cell proliferation gene within cancerous cells could force said c…
ISEF · 2024
Cellular and Molecular Biology
Immunotherapy involves exposing patients to small amounts of the allergen to desensitize their immune systems. This can be dangerous to patients who experience anaphylactic reactions to the…
ISEF · 2024
Cellular and Molecular Biology
Metals and their transporters influence cell behavior in cancer, and previous research demonstrated that manganese promotes malignancy. Therefore, if metal transporters are essential in main…
ISEF · 2024
Cellular and Molecular Biology
Despite increasing cancer incidence globally, few alternative treatments to chemotherapy and radiation exist. These standard therapies require specialized equipment, are costly, and have ser…
ISEF · 2024
Cellular and Molecular Biology Second Award
Selenoprotein O (SelO) is a mitochondrial pseudokinase enzyme that AMPylates, or transfers an AMP molecule to, cellular proteins. However, SelO’s role as an AMPylator in oxidative stress res…
ISEF · 2024
Cellular and Molecular Biology Third Award
Breast cancer, annually affecting over 2.3 million people worldwide, is targeted in this study through the epichaperome, a network of proteins including heat shock protein 90 (HSP90). PUH71,…
ISEF · 2024
Cellular and Molecular Biology
Hepatocellular carcinoma (HCC) is the most prominent type of liver cancer around the world, and it ranks as the fourth leading cause of cancer death worldwide with these rates only rising. D…
ISEF · 2024
Cellular and Molecular Biology
The intestines are a crucial part of the digestive system, aiding in digestion and nutrient absorption. They feature a columnar barrier of intestinal epithelial cells, called the intestinal…
ISEF · 2024
Cellular and Molecular Biology Third Award
Fibrodysplasia Ossificans Progressiva(FOP) is an extremely rare and debilitating bone disorder that affects 0.00005% of the population. The defining characteristic of FOP is severe heterotop…
ISEF · 2024
Cellular and Molecular Biology
Humanity is always looking for the next fix, and because of this we have created and used many different substances. In this study nicotine, vaporizer liquids, and CBD oils were tested to se…
ISEF · 2024
Cellular and Molecular Biology
Alzheimer’s disease (AD) is the leading cause of dementia, accounting for 60-80% of cases in the United States. Failed interventions, aimed at the symptoms of the disease, have created a dri…
ISEF · 2024
Cellular and Molecular Biology Fourth Award
The p53 gene is a tumor suppressor in the human body that is mutated in 50-60% of human cancers. p53 acts to suppress retrotransposons (jumping genes) within the genome which are prevalent i…
ISEF · 2024
Cellular and Molecular Biology
Gastric adenocarcinoma is the fourth most common cancer in Brazil. . Symptoms appear at a more advanced stage of the disease, weight loss, anorexia, dysphagia, epigastric pain, melena and ea…
ISEF · 2024
Cellular and Molecular Biology
Cancer is a worldwide problem, especially breast cancer in women, with the treatment options consisting primarily of chemotherapy. It is not only very expensive but it is known to target fas…