38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2022
Cellular and Molecular Biology
High rates of mortality are associated with low rates of stem cell regeneration in the intestine post irradiation. Low cell self-renewal is also associated with numerous terminal gastrointes…
ISEF · 2022
Cellular and Molecular Biology
The purpose of this project is to reveal the mechanism of CENP-E (a microtubule dynamic protein) mediated mitochondrial dynamics during mitotic process, and to interpret the difference betwe…
AJAS · 2022
Cellular Science
Cartilage, when subjected to low-gravity environments, tends to degrade or weaken. A cell rocker was used to simulate the effects of microgravity through the use of fluid shear tension’s pro…
ISEF · 2022
Cellular and Molecular Biology
Tetracycline is an antibiotic that treats bacterial infections by acting as protein synthesis inhibitor through disruption of bacterial translation. Overuse of tetracycline has led to its re…
ISEF · 2022
Cellular and Molecular Biology
Neurogenesis is highly crucial to the success of the nervous system, and perturbation of this process has the potential to elicit disease states. A better understanding has implications for…
ISEF · 2022
Cellular and Molecular Biology
My research was on the uses of cellulase and how it breaks down cellulose. For example, in aiding cellulose digestion. The results of my experiment agreed with my hypothesis. My results were…
ISEF · 2022
Cellular and Molecular Biology Second Award
Methylmercury is a neurotoxin present in fish tissues that permeates the blood-brain barrier (BBB) after consumption. Previous research has shown that methylmercury is harmful to neurons, ca…
ISEF · 2022
Cellular and Molecular Biology Fourth Award
Ribosome biogenesis is critical for cell proliferation and survival as ribosomes catalyze the synthesis of proteins, and regulation of protein synthesis is crucial for control of gene expres…
ISEF · 2022
Cellular and Molecular Biology
The purpose of this study was to assess the possible role of Synaptopodin, a protein crucial to cellular development, within sensory neurons. This query was investigated within the context o…
ISEF · 2022
Cellular and Molecular Biology Third Award
According to the Cystic Fibrosis (CF) Foundation, over 70,000 people across the globe suffer from CF, and the life expectancy of patients with CF drops to about the age of 44. CF is an autos…
ISEF · 2022
Cellular and Molecular Biology
Genome instability, an enabling hallmark of cancer, drives carcinogenesis. Genomic stability depends upon the ability of the cell to exercise the DNA Damage Response and to repair its damage…
ISEF · 2022
Cellular and Molecular Biology
In our world, there is concern about environmental quality, including the impact of air pollution, and to a lesser extent, ionizing radiation. The Purple Heart Spiderwort (Tradescantia palli…
ISEF · 2021
Cellular and Molecular Biology
The ability to precisely measure cell permeability will be a necessary asset in the future development of intracellular antibiotics. The efficacy of the antibiotic vancomycin is reliant on c…
ISEF · 2021
Cellular and Molecular Biology
The transforming growth factor beta (TGFB) superfamily consists of a group of regulatory proteins that bind to membrane receptors and generate an intracellular signal to regulate cellular pr…
ISEF · 2021
Cellular and Molecular Biology
The purpose of this project is to see if Atrazine passes its negative effect on the sensory, motor, and learning behaviors of planaria to the second generation planaria. The second generatio…
ISEF · 2021
Cellular and Molecular Biology
Oxidative stress produces macromolecular damage. It is implicated in several disease states such as cancer, aging and neurodegenerative disorders. Therefore, it is necessary to find solution…
ISEF · 2021
Cellular and Molecular Biology Fourth Award
Adeno-associated virus (AAV) 9 and its variants are promising vectors for gene therapy to treat neurological diseases. The clinical uses of AAV9 along with its variants are leveraged by the…
ISEF · 2021
Cellular and Molecular Biology
Amyloid-beta (Aß) and insulin, two substrates of insulin-degrading enzyme (IDE), are critically important in the pathogenesis of Alzheimer's disease (AD) and type 2 diabetes (T2D), respectiv…
ISEF · 2021
Cellular and Molecular Biology
A big question in the neuroscience community pertaining to our sense of smell is how the olfactory cortex is able to distinguish between millions of odors. I hypothesized that chemical compo…
ISEF · 2021
Cellular and Molecular Biology
The genome of cells is like an instruction book, telling cells what to do and how to do it. A behavior embedded in the genome of cancer cells known as “tumor self-seeding” (the tendency for…
ISEF · 2021
Cellular and Molecular Biology Second Award
Common genetic diseases—systemic diseases caused by thousands of mutations—affect millions of people around the world. Many of these mutations fall within regulatory regions. While the mutat…
ISEF · 2021
Cellular and Molecular Biology
Over one million individuals in the United States are addicted to cocaine, yet limited knowledge of underlying molecular mechanisms prevents effective treatment development. Chronic cocaine…
ISEF · 2021
Cellular and Molecular Biology Fourth Award
The bacterium Pseudomonas aeruginosa causes many human and plant diseases, infecting over 50,000 people annually. ~75% of Pseudomonas proteins are characterized; however, pathogenic mechanis…
ISEF · 2021
Cellular and Molecular Biology
My project is an assay of the involvement of HYPE (huntingtin yeast-interacting partner E) in the translocation of BiP (binding immunoglobulin protein) to the cell surface. BiP is the master…
ISEF · 2021
Cellular and Molecular Biology
Cancer cells are formed when mitosis, the asexual reproduction of cells, becomes uncontrollable and cells can no longer send or receive signals concerning their own growth. The purpose of th…
ISEF · 2021
Cellular and Molecular Biology
Biofuels currently are produced through the fermentation of agricultural products. However, due to the growing issue of world hunger an alternative biofuel material was research. With refere…
ISEF · 2021
Cellular and Molecular Biology
Fibroblast growth factors (FGFs) influence growth, migration and survival of cells as well as cell division in mammary gland development. FGF signaling deregulation can thus cause formation…
ISEF · 2021
Cellular and Molecular Biology Fourth Award
T-cells are a class of lymphocytes that play an essential role in adaptive immunity and are known to develop in the thymus. However, functional T-cells are also found in animals lacking a th…
ISEF · 2021
Cellular and Molecular Biology
Prochlorococcus is a cyanobacterium that produces 20% of Earth’s oxygen. This organism is a key organism for balancing global CO2 levels. However, anthropogenic CO2 production exceeds the ab…
ISEF · 2021
Cellular and Molecular Biology
Lung adenocarcinoma (LUAD) accounts for forty percent of all lung cancer cases in the United States. Treatment currently focuses on surgery and chemotherapy but survival rates remain lower t…