38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2025
Biomedical Engineering Fourth Award
Problem Most drug development costs go toward testing failed drug candidates, slowing innovation and ultimately costing lives. Even then, cardiotoxicity is a leading cause of drug recalls, s…
ISEF · 2025
Chemistry Fourth Award
Hydrogen is a promising clean energy carrier, yet current production methods remain either carbon-intensive or economically unsustainable. Recently, attention has shifted to serpentinization…
ISEF · 2025
Translational Medical Science Fourth Award
In 2024 the American Cancer Society (ACS) reported a 78% death rate for pancreatic cancer. The 5-year survival rate for pancreatic cancer is 13%. ACS states the only effective method known t…
ISEF · 2025
Robotics and Intelligent Machines Fourth Award
Over 300,000 cetaceans die every year due to human activity–primarily ship collisions and fishing entanglements–with roughly 67% of all whale deaths attributed to human interactions. Many wh…
ISEF · 2025
Mathematics Fourth Award
To improve artificial vision systems, human vision should be better understood. Many aspects of human vision are tuned to the characteristics of its natural inputs. These characteristics inc…
ISEF · 2025
Behavioral and Social Sciences Fourth Award
I use "spatial capital" to refer to the potential for socioeconomic mobility in urban locations. I hypothesize that spatial capital adhere's to Piketty's r > g dynamic for financial capital,…
ISEF · 2025
Environmental Engineering Fourth Award
The excessive use of polystyrene (PS) in packaging has led to severe environmental concerns due to its non-biodegradability, large contribution to microplastic pollution, and harmful chemica…
ISEF · 2025
Behavioral and Social Sciences Fourth Award
Animals can engage in lifelong learning because they can form, consolidate, and recall memories. Because sleep plays a vital role in consolidating newly acquired information and aiding recal…
ISEF · 2025
Environmental Engineering Fourth Award
Water pollution is a pressing global issue, exacerbated by inefficient wastewater treatment technologies that fail to remove emerging contaminants such as pharmaceuticals, antibiotics, and a…
ISEF · 2025
Engineering Technology: Statics & Dynamics Fourth Award
Drones are widely used in military and civilian applications, with VTOL (Vertical Takeoff and Landing) drones combining the vertical lift capability of helicopters with the horizontal cruisi…
ISEF · 2025
Earth and Environmental Sciences Fourth Award
Lake-effect precipitation, which significantly impacts regions downwind of the Great Lakes, poses unique forecasting challenges due to its dependence on localized processes and intricate int…
ISEF · 2025
Materials Science Fourth Award
Over 40% of chemotherapy patients suffer toxic side effects due to non-specific targeting, and most genetic therapies are prematurely degraded before they can reach target organs, limiting t…
ISEF · 2025
Physics and Astronomy Fourth Award
Flexible two-dimensional (2D) field-effect transistors (FETs) have gathered great interest, due to the need to solve scalability problems that are commonplace in 3D FETs. Specifically, the r…
ISEF · 2025
Biochemistry Fourth Award
Ionizable lipid nanoparticles (LNPs) are the mainstream delivery mechanisms for mRNA therapeutics. pH-sensitive protonation allows their membranes to favorably (de)stabilize based on the sur…
ISEF · 2025
Chemistry Fourth Award
Over 350 million tons of plastic waste are produced annually while less than 10% is recycled. Through catalytic hydrogenolysis, plastic waste can be converted into diesel with strontium tita…
ISEF · 2025
Biomedical and Health Sciences Fourth Award
Model for End-Stage Liver Disease (MELD)score, a widely used tool, predicts 90-day waitlist-mortality but fails to account for post-transplant survival, leading to suboptimal organ allocatio…
ISEF · 2025
Translational Medical Science Fourth Award
Acquired drug resistance is one of the biggest obstacles in cancer treatment, leading to increased chances of cancer relapses and progression. To combat drug resistances and to improve treat…
ISEF · 2025
Microbiology Fourth Award
The dengue virus infects over 400 million people each year and can lead to organ failure and death. Until 2024, there was only one current vaccine option for dengue; however, studies have sh…
ISEF · 2025
Biochemistry Fourth Award
Biochemical signaling plays a key role in molecular pathways in various disease processes of women’s reproductive health. Polycystic Ovarian Syndrome (PCOS) affects 66 million reproductive-a…
ISEF · 2025
Computational Biology and Bioinformatics Fourth Award
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline severe enough to interfere with daily activities. Current diagnostic methods, such as…
ISEF · 2025
Computational Biology and Bioinformatics Fourth Award
Climate change poses a significant threat to global ecosystems. Current mitigation strategies are inefficient and costly. Biological solutions, specifically algae, offer a promising alternat…
ISEF · 2025
Behavioral and Social Sciences Fourth Award
The global mental health crisis, affecting over 970 million people, presents significant societal and economic challenges, highlighting the urgent need for effective mental health assessment…
ISEF · 2025
Plant Sciences Fourth Award
Traditional evapotranspiration (ET) based irrigation technique involves uncertainties from different sources including ET data and crop coefficients resulting in over- or under-irrigation. W…
ISEF · 2025
Chemistry Fourth Award
Wounds cause 5–6 million deaths annually, and current treatments remain inadequate, emphasizing the need for advanced wound care systems. This study aimed to address this gap by developing i…
ISEF · 2025
Biomedical Engineering Fourth Award
Gliomas affect 90,000 people annually in the United States and have 5-year survival rates as low as 7%, largely due to 5-year recurrence rates of 52-62%. Current imaging techniques rely on c…
ISEF · 2025
Environmental Engineering Fourth Award
Climate change is greatly attributed to an excess of greenhouse gasses trapping heat in the Earth's atmosphere. Livestock digestive function contributes to a portion of these emissions, sugg…
ISEF · 2025
Biomedical and Health Sciences Fourth Award
Botulinum neurotoxin type A (BoNT/A) represents a serious biological threat to global public health due to its extreme toxicity and its prolonged persistence. Recently, several camelid singl…
ISEF · 2025
Biomedical Engineering Fourth Award
Diabetes is one of the leading causes of death and chronic disease in the United States. Current glucose monitoring devices require painful blood sticks that lead to poor monitoring adherenc…
ISEF · 2025
Engineering Technology: Statics & Dynamics Fourth Award
Learning to skateboard is challenging and often leads to injury. Unlike bikes, skateboards do not have a universal training aid for beginners. This project aimed to create a device similar t…
ISEF · 2025
Computational Biology and Bioinformatics Fourth Award
MicroRNAs (miRNAs) with highly dysregulated expression levels, have so far constituted the focus of disease-specific biomarkers research. However, the complex regulating mechanisms between m…