Search past science fair projects

MyoAssist: An Innovative AI-Based, User-Driven Exoskeletal Assistive Control System for Individuals With Movement Disabilities

Robotics and Intelligent Machines First Award

Nearly 1 in 8 people in the U.S. suffer from movement disorders, significantly impacting their quality of life. Neuromuscular disabilities cost the healthcare system $420 billion annually. D…

NeuroFlex: A Cost-Effective, Non-Invasive EEG-Controlled Bionic Prosthesis for Transfemoral Amputees

Biomedical Engineering First Award

Current lower limb prostheses rely on cumbersome procedures, need risky surgery, and are prohibitively expensive. As a result, many lower-limb amputees experience unnatural gait patterns and…

Novel Design and Total Synthesis of Aza-C-Nucleosides From Furfuryl Alcohol, the Key to Fighting RNA Viral Diseases

Chemistry First Award

In our research we focused on antivirotics, broad-spectrum drugs against RNA viral diseases. Galidesivir, a molecule that today appears to be the most optimal inhibitor of viral RdRp, became…

OncoNote: Enabling the Discovery of a Novel Digital Biomarker for Early Pan-Cancer Survival and Recurrence Prediction via Free-Text Clinical Narratives

Translational Medical Science First Award

Cancer is the second leading cause of death worldwide, affecting 20 million people and being responsible for >9.7 million deaths annually. Early prediction of clinical outcomes is crucial fo…

Optimizing Aquatic Oil Spill Clean Up: Oil Viscosity and Ferrofluid Composition

Earth and Environmental Sciences First Award

In 2024, over 10,000 tons of oil were spilled into the ocean, damaging the environment and costing billions of dollars in mitigation efforts. This project is a continuation of previous resea…

Paving the Path to the Impossible: Regenerating Neurons Using Prostaglandin E2 Regulation as a Therapeutic Strategy

Biomedical and Health Sciences First Award

Nerve degeneration, due to acute injury and chronic neurodegenerative disease, causes devastating symptoms for millions of patients worldwide. No therapeutics to regenerate neurons exist, me…

StutterZero: End-to-End Speech Conversion to Transcribe and Correct Stutters

Computational Biology and Bioinformatics First Award

Over 70 million in the world suffer from stuttering, a speech impairment characterized by involuntary disruptions during normal speech. This can create communication barriers and limiting ac…

The Effect of Histone Modifications Induced by Ack sRNAs on Ac Transposable Elements

Cellular and Molecular Biology First Award

Chromosomal rearrangements caused by mobile transposons (TEs) are implicated in human cancers and neurological disorders. The Ac element of the Ac(Activator)/Ds(Dissociation) TE system, foun…

The Novel Role of KRT Proteins as Biomarkers in the Dysregulated Neuroendocrine System of ALS for Early Diagnosis With PT150 as a Novel Multi-Target Neuroprotective Therapeutic

Computational Biology and Bioinformatics First Award

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by motor neuron degeneration. Although biomarkers have been identified, they lack specificity. Combined with…

Theoretical and Experimental Investigation of Ship Wakes

Physics and Astronomy First Award

In this study, we investigate the formation and characteristics of ship wakes. The longstanding explanation of a constant wake angle, independent of any ship parameters, has been questioned…

The Prisoner's Dilemma: Strategy Dynamics Related to Memory and Selfishness

Mathematics First Award

Understanding whether selfish or altruistic behavior benefits an individual more remains challenging using traditional approaches like studying human samples. The prisoner's dilemma, a game…

Utilizing Food Waste to Produce Biodegradable Packaging Material,

Environmental Engineering First Award

A Bioinformatic Analysis of Foliar Fungal Endophytes in Litter Decomposition

Microbiology First Award

Plant litter decomposition is a key ecological process that plays a vital role in the global carbon cycle. While the effect of soil microbes on decomposition has been well studied, the role…

Acoustic Filtration: Harnessing Ultrasonic Technology for the Streamlined Removal of Microplastic Particles From Water Flow

Earth and Environmental Sciences First Award

Microplastics have become a prevalent global environmental issue, with an estimated 75 trillion microplastics in the oceans today. MPs pose dangers to wildlife and cause serious health issue…

Advancing Early Detection of Kidney Cancer (Year 3): A Novel Automated Workflow for High-Throughput Proteomic Profiling of Urinary Extracellular Vesicles

Translational Medical Science First Award

Renal Cell Carcinoma (RCC) is the world's deadliest urological disease. Although detection before metastasis can raise a patient's 5-year survival rate by over 75%, current diagnostic method…

Advancing Sustainable Citrus Greening Disease Management: A Comprehensive Eco-Friendly Approach for the Management of Candidatus Liberibacter asiaticus Using Trunk Injection of Murraya koenigii Derived Biological Extract and Its Validation Through Precision Agriculture Tools

Plant Sciences First Award

Huanglongbing (HLB), or the Citrus Greening (Candidatus Liberibacter asiaticus), is the most destructive citrus disease worldwide and persists in threatening the sustainability of the Citrus…

Analyzing Per- and Polyfluoroalkyl Substances (PFAS) Through Atomistic Simulations

Chemistry First Award

Per- and polyfluoroalkyl substances (PFAS), a class of highly fluorinated hydrocarbons, pose global contamination and pollution concerns due to both their toxicity and their potential to inc…

ANOMaLY: A Real-Time Globalized System for Effective Regional Mitigation of Agricultural Nitrous Oxide Emissions

Earth and Environmental Sciences First Award

Nitrous oxide (N2O) is one of the largest contributors to the greenhouse effect (265x more greenhouse forcing than CO2) and is the largest contributor to ozone depletion in the 21st century.…

A Novel Approach to Characterizing Pathogenicity of SLC25A13 Variants in Cancer

Biochemistry First Award

A hallmark of cancer is the rewiring of cellular metabolism to meet proliferative needs. Citrin protein (transcribed from the human SLC25A13 gene) is a mitochondrial carrier involved in the…

A Novel Hadronization Model Explaining Charm-Quark Hadronization in Different Collision Systems Through Yet-Unobserved Excited States and Cluster Volume Dependence

Physics and Astronomy First Award

The study of hadronization, the process of quarks combined into hadrons, is pivotal for understanding the universe's formation, yet current theories inadequately explain this process. This s…

Burlap Mycofiltration of Heavy Metal Water Pollution via White Rot Fungi

Environmental Engineering #2 First Award

Decoding ASXL3: A Novel Biomarker for Neurodevelopmental Disorders

Cellular and Molecular Biology First Award

In a recent study, 33% of individuals with neurodevelopmental disorders (NDDs) carried mutations in ASXL3, whose function is unknown. To understand ASXL3’s role in NDDs, we used CRISPR techn…

Determining the Distribution of Arginine in Gracilaria salicornia and Codium edule and Fibropapillomatosis Rates in Chelonia mydas in Kane?ohe Bay

Animal Sciences First Award

Populations of green sea turtles (Chelonia mydas) in Hawaii have become a source of concern over the past decade due to the tumor-causing disease fibropapillomatosis (FP), the number one cau…

Development of a Cathepsin B-Responsive Hydrogel for Targeted Delivery of Cancer Immunotherapy

Biochemistry/ Molecular Biology First Award

Diffusion-Based Conditional Mesh Synthesis for Rapid 3D Visual Design

Technology Enhances the Arts First Award

As digital design has become ubiquitous over the last few decades, 3D creations have become much more advanced through Computer-Aided Design (CAD). However, this approach can be tedious, tim…

Dim Asteroids Discovered! Rapidly Finding and Tracking Faint Near-Earth Asteroids Using an Accurate Deep Learning Based Process

Physics & Astronomy First Award

Effective Robotic Swarm Controller Applied to Autonomous Swarm Assembly of Modular Flexible Production Lines

Robotics and Intelligent Machines First Award

The primary aim of this project is to design and implement a robotic swarm controller capable of path planning and task allocation, performing diverse assignments in a dynamic environment. A…

Electrogastrography and Personalized Transcutaneous Electrical Nerve Stimulation for Noninvasive, Low-Cost Diagnosis and Treatment of Gastroparesis

Biomedical Engineering First Award

Gastroparesis, characterized by slowed or absent gastric contractions, affects 1.8% of the population, presents with severe nausea, abdominal pain, a high mortality rate, and incurs high tre…

Evolutionary Insights Into the Stemness Paradox of Human Germ Cells and Cancer Cells

Biomedical and Health Sciences First Award

Primates had evolved an advanced spermatogonia stem cell (SSC) system that correlates with reduced germline mutations and longer lifespans, yet the underlying mechanism remains poorly unders…

GaitNet: A Medically Interpretable Video-Based System for Assessing Parkinsonian Gait Impairment Severity Using 2-Stream Spatiotemporal Neural Network

Behavioral and Social Sciences First Award

Parkinson’s disease (PD) affects millions of people worldwide and causes gait impairments like tremors. Accurate motor impairment assessment is critical for efficient PD management. The MDS-…